Born in BloodSworn in Blood......isn't only the motto the Famiglia lives by. Bleeding for love is something every couple in this book has experienced. Through hardships their love morphs into something even more beautiful and resilient. A love each of them is willing to fight for.This anthology contains stories for the following couples: Aria & LucaRomero & LilianaGrowl & CaraMauro & StellaMatteo & Gianna
The second novel in the international No. 1 bestselling Mercy Thompson series - the major urban fantasy hit of the decade. 'I love these books!' Charlaine Harris 'The best new fantasy series I've read in years' Kelley Armstrong MERCY THOMPSON: MECHANIC, SHAPESHIFTER, FIGHTER Like most people who own their own business, I work long hours that start early in the morning. So when someone calls me in the middle of the night, they'd better be dying ... Mechanic Mercy Thompson is woken at 3am by a vampire calling in a favour. He has to deliver a message to a fellow undead and needs a witness that won't be noticed - and Mercy's shapeshifting abilities make her the perfect candidate. But the assignment turns into a bloodbath and Mercy attracts the attention of not just a powerful vampire, but the even more powerful demon possessing him. She can count on the supernatural community for protection - and alpha werewolf Adam would like her to rely on him in other ways too - but when it comes to being proactive, she's on her own. Praise for the series: 'Plenty of twists and turns . . . Kept me entertained from its deceptively innocent beginning to its can't-put-it-down end' Kim Harrison, bestselling author of Dead Witch Walking 'I enjoyed every minute of it. I love Mercy and can't wait for her to kick some more ass' Lilith Saintcrow The Mercy Thompson books: Moon Called Blood Bound Iron Kissed Bone Crossed Silver Borne River Marked Frost Burned Night Broken Fire Touched Silence Fallen Storm Cursed Shifting Shadows (Stories from the world of Mercy Thompson)
Jae is a slave in a dying desert world. Once verdant with water from a magical Well, the land is drying up, and no one remembers the magic needed to keep the water flowing. If a new source isn’t found soon, the people will perish. Jae doesn’t mind, in a way. By law, she is bound by a curse to obey every order given her, no matter how vile. At least in death, she’ll be free. Elan’s family rules the fading realm. He comes to the estate where Jae works, searching for the hidden magic needed to replenish the Well, but it’s Jae who finds it, and she who must wield it. Desperate to save his realm, Elan begs her to use it to locate the Well. But why would a slave—abused, beaten, and treated as less than human—want to save the system that shackles her? Jae would rather see the world burn. Though revenge clouds her vision, she agrees to help if the realm’s slaves are freed. Then Elan’s father arrives. The ruler’s cruelty knows no limits. He is determined that the class system will not change—and that Jae will remain a slave forever. "Ferocious and intelligent." —Kirkus Reviews "Allen’s lush debut mixes current, pressing questions with fantasy while exploring systematic injustice and historical oppression...readers will clamor for the sequel." —Publishers Weekly
Most can't touch the power, but Liv Warren is special. A paranormal tracker who follows the scent of blood, Liv makes her own rules and the most important one is trust no one. When her friend's daughter goes missing, Liv has no choice but to find the young girl. And thanks to a childhood oath, she can't rest until the child is home safe. Except that means trusting Cam Caballero the former lover forbidden to her. Bound by oath and lost in desire for a man she cannot have, Liv is racing to save the child from a dark criminal underworld where secrets, lies, trauma and danger lurk around every corner, every touch and every kiss... But more blood will be spilled before it's over
Beautiful. Gorgeous. Slut.Whore. I've been called all of these, except my true name--a secret I've never learned.I was groomed for a life of captivity; brought up as a slave for the exclusive club, Exotique. I'm desired for my body and thirsted after for my addictive blood. I'm stripped and restrained while male after male acts out his twisted desires.I'm constantly at war with myself while my inner beasts battle for dominance. The succubus half of me craves these sessions. She longs for the toxic mix of pleasure and pain, feasting on the release of others. My phoenix half lies dormant. She's a silent presence who shudders at the crack of a whip, and shies away from the cruel hands of my handlers.While I suffer through countless degrading sessions, somewhere far away a trio of Phoenix warriors are sanctioned by their King to find and rescue me. Will they succeed? Or will one of my handlers finally take a session too far?Their race is dying, but so am I.Bound for Blood is book one in the Feathers and Fire series. It is a Dark, Paranormal, Reverse Harem romance. The final book ends with an HEA. Expect dark elements and explicit scenes. If such scenes might trigger or offend you, please do not buy this book.
I should hate them, yet there's no denying my body reacts to their every touch. When my ancestors lost everything in a business deal gone wrong, they were forced to make a sacrifice-a blood oath, promising the firstborn daughter of their bloodline to a league of vampires. And now they've come to collect. Atlas. Kade. Gabriel. Lex. All seductively sexy and unimaginably dangerous. Torn from everything I've ever known, they take me captive in their Washington, D.C. mansion. Each is determined to own me-body, heart, and soul. I'd be lying if I said the thought of that didn't make my skin tingle in anticipation. Still, the alluring immortals are in for a surprise, because ancient debt aside, I'm not going down without a fight. Bound in Crimson is the first installment in a sinfully sexy reverse harem paranormal romance series that is sure to leave readers gasping for more!
A clear, straightforward resource to guide you through preclinical drug development Following this book's step-by-step guidance, you can successfully initiate and complete critical phases of preclinical drug development. The book serves as a basic, comprehensive reference to prioritizing and optimizing leads, dose formulation, ADME, pharmacokinetics, modeling, and regulations. This authoritative, easy-to-use resource covers all the issues that need to be considered and provides detailed instructions for current methods and techniques. Each chapter is written by one or more leading experts in the field. These authors, representing the many disciplines involved in preclinical toxicology screening and testing, give you the tools needed to apply an effective multidisciplinary approach. The editor has carefully reviewed all the chapters to ensure that each one is thorough, accurate, and clear. Among the key topics covered are: * Modeling and informatics in drug design * Bioanalytical chemistry * Absorption of drugs after oral administration * Transporter interactions in the ADME pathway of drugs * Metabolism kinetics * Mechanisms and consequences of drug-drug interactions Each chapter offers a full exploration of problems that may be encountered and their solutions. The authors also set forth the limitations of various methods and techniques used in determining the safety and efficacy of a drug during the preclinical stage. This publication should be readily accessible to all pharmaceutical scientists involved in preclinical testing, enabling them to perform and document preclinical safety tests to meet all FDA requirements before clinical trials may begin.
Hayes’ Principles and Methods of Toxicology has long been established as a reliable reference to the concepts, methodologies, and assessments integral to toxicology. The new sixth edition has been revised and updated while maintaining the same high standards that have made this volume a benchmark resource in the field. With new authors and new chapters that address the advances and developments since the fifth edition, the book presents everything toxicologists and students need to know to understand hazards and mechanisms of toxicity, enabling them to better assess risk. The book begins with the four basic principles of toxicology—dose matters, people differ, everything transforms, and timing is crucial. The contributors discuss various agents of toxicity, including foodborne, solvents, crop protection chemicals, radiation, and plant and animal toxins. They examine various methods for defining and measuring toxicity in a host of areas, including genetics, carcinogenicity, toxicity in major body systems, and the environment. This new edition contains an expanded glossary reflecting significant changes in the field. New topics in this edition include: The importance of dose–response Systems toxicology Food safety The humane use and care of animals Neurotoxicology The comprehensive coverage and clear writing style make this volume an invaluable text for students and a one-stop reference for professionals.
Physiology is a comprehensive presentation of core physiologic concepts with a focus on mechanisms. Renowned physiology instructor Linda S. Costanzo covers important concepts in the field, both at the organ system and cellular levels. Easy to read and user-friendly, the revised fourth edition stresses essential and relevant content with absolute clarity and includes concise step-by-step explanations complemented by numerous tables and abundant illustrations. It provides information on the underlying principles of cellular physiology, the autonomic nervous system, and neurophysiology, as well as the cardiovascular, respiratory, renal, acid-base, gastrointestinal, endocrine, and reproductive organ systems. This book is ideal as both a textbook and as a review guide for the boards. Provides step-by-step explanations and easy-to-follow diagrams clearly depicting physiologic principles. Integrates equations and sample problems throughout the text. Presents chapter summaries for quick overviews of important points. Contains boxed Clinical Physiology Cases to provide you with more clinical examples and a more thorough understanding of application. Provides questions at the end of each chapter for an extensive review of the material and to reinforce your understanding and retention. Offers a full-color design and all full-color illustrations throughout. Features increased coverage of pathophysiology in the neurophysiology, gastrointestinal, renal, acid-base, and endocrine chapters to emphasize this important component of the USMLE exam. Incorporates further practice in solving physiology equations through the inclusion of additional problem-solving questions throughout the text.
