A Biography of Paul Berg
A Biography of Paul Berg

Author: Errol C. Friedberg

Publisher: World Scientific Publishing Company

Published: 2014

Total Pages: 0

ISBN-13: 9789814569040

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With a Foreword by Sydney Brenner (Nobel laureate in Physiology or Medicine, 2002) This biography details the life of Paul Berg (Emeritus Professor at Stanford University), tracing Berg's life from birth, in 1926, to the present, with special emphasis on his enormous scientific contributions, including being the first to develop technology that led to gene cloning science. In 1980, Berg received a Nobel Prize in chemistry for this work. In addition to his contributions in the research laboratory, Berg orchestrated and oversaw a historic meeting at Asilomar, California that centered on a threatening controversy surrounding the perception by some of the harmful potential of recombinant DNA technology. This meeting did much to forestall this controversy and to put in place the regulation of recombinant DNA work, thus putting fears to rest. The recombinant DNA controversy was a historic outcome of the discovery of gene cloning. Notably, it represented a paramount example of scientific foresight and due diligence by the scientific community, rather than by regulatory entities in the United States and many other countries. The ultimate acceptance of gene/DNA cloning led to a new era of modern biology that thrives to the present. This book is aimed primarily at scientists and those in training. The book strives to simply provide information for the general reader, but is not specifically tailored for a general reading audience. While many books cover the recombinant DNA controversy, none have satisfactorily addressed this historic period and are often contradictory about the many who's, where's, and why's involved. Additionally, the great majority of these were written by non-scientists. This biography of Paul Berg provides access to numerous archived letters and documents at Stanford University not previously addressed, and to the chronology of events as recalled and documented by him, as well as other key personalities, many of whom were interviewed.

Biography Of Paul Berg, A: The Recombinant Dna Controversy Revisited
Biography Of Paul Berg, A: The Recombinant Dna Controversy Revisited

Author: Errol C Friedberg

Publisher: World Scientific

Published: 2014-06-17

Total Pages: 443

ISBN-13: 9814569062

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With a Foreword by Sydney Brenner (Nobel laureate in Physiology or Medicine, 2002)This biography details the life of Paul Berg (Emeritus Professor at Stanford University), tracing Berg's life from birth, in 1926, to the present, with special emphasis on his enormous scientific contributions, including being the first to develop technology that led to gene cloning science. In 1980, Berg received a Nobel Prize in chemistry for this work.In addition to his contributions in the research laboratory, Berg orchestrated and oversaw a historic meeting at Asilomar, California that centered on a threatening controversy surrounding the perception by some of the harmful potential of recombinant DNA technology. This meeting did much to forestall this controversy and to put in place the regulation of recombinant DNA work, thus putting fears to rest.The recombinant DNA controversy was a historic outcome of the discovery of gene cloning. Notably, it represented a paramount example of scientific foresight and due diligence by the scientific community, rather than by regulatory entities in the United States and many other countries. The ultimate acceptance of gene/DNA cloning led to a new era of modern biology that thrives to the present.This book is aimed primarily at scientists and those in training. The book strives to simply provide information for the general reader, but is not specifically tailored for a general reading audience.While many books cover the recombinant DNA controversy, none have satisfactorily addressed this historic period and are often contradictory about the many who's, where's, and why's involved. Additionally, the great majority of these were written by non-scientists. This biography of Paul Berg provides access to numerous archived letters and documents at Stanford University not previously addressed, and to the chronology of events as recalled and documented by him, as well as other key personalities, many of whom were interviewed.

Genes, Germs And Medicine: The Life Of Joshua Lederberg
Genes, Germs And Medicine: The Life Of Joshua Lederberg

Author: Jan Sapp

Publisher: World Scientific

Published: 2021-02-23

Total Pages: 424

ISBN-13: 9811225494

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Genes, Germs and Medicine explores the development of modern biomedical science in the United States through the life of one of the Twentieth Century's most influential scientists.Joshua Lederberg was a scientific renaissance man. He and his collaborators founded the field of bacterial genetics, and he was awarded the Nobel Prize at the age of 33 (the second youngest in history). He helped to lay the foundations for genetic engineering, made fundamental revisions to immunological and evolutionary theory, and developed medical genetics. He initiated the search for extraterrestrial microbial life, developed artificial intelligence, and was a visionary of the Digital Age. Lederberg coined some of the central terms of modern biology: plasmid, transduction, exobiology, euphenics and microbiome.A complex humanist who spoke out for social justice, Lederberg confronted racism, and denied a gene-centered view of humans. Pondering our social evolution outside of nature, he forewarned of the complex ethical issues arising from bioengineering. He sounded the alarm about coming pandemics at a time when few would listen, and warned of the peril of biowarfare and strove to prevent it. Lederberg was a man with a deep sense of social and intellectual responsibility, a trusted advisor to eight presidential administrations.

CRISPR People
CRISPR People

Author: Henry T. Greely

Publisher: MIT Press

Published: 2021-02-16

Total Pages: 400

ISBN-13: 0262362732

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What does the birth of babies whose embryos had gone through genome editing mean--for science and for all of us? In November 2018, the world was shocked to learn that two babies had been born in China with DNA edited while they were embryos--as dramatic a development in genetics as the cloning of Dolly the sheep was in 1996. In this book, Hank Greely, a leading authority on law and genetics, tells the fascinating story of this human experiment and its consequences. Greely explains what Chinese scientist He Jiankui did, how he did it, and how the public and other scientists learned about and reacted to this unprecedented genetic intervention.

Biotechnology and Society
Biotechnology and Society

Author: Hallam Stevens

Publisher: University of Chicago Press

Published: 2016-10-06

Total Pages: 404

ISBN-13: 022604615X

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With Biotechnology and Society, Hallam Stevens offers an up-to-date primer to help us understand the interactions of biotechnology and society and the debates, controversies, fears, and hopes that have shaped how we think about bodies, organisms, and life in the twenty-first century. Stevens addresses such topics as genetically modified foods, cloning, and stem cells; genetic testing and the potential for discrimination; fears of (and, in some cases, hopes for) designer babies; personal genomics; biosecurity; and biotech art. Taken as a whole, the book presents a clear, authoritative picture of the relationship between biotechnology and society today, and how our conceptions (and misconceptions) of it could shape future developments. It is an essential volume for students and scholars working with biotechnology, while still being accessible to the general reader interested in the truth behind breathless media accounts about biotech’s promise and perils.

Discovering Precision Health
Discovering Precision Health

Author: Lloyd Minor

Publisher: John Wiley & Sons

Published: 2020-01-28

Total Pages: 288

ISBN-13: 1119672694

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Today we are on the brink of a much-needed transformative moment for health care. The U.S. health care system is designed to be reactive instead of preventive. The result is diagnoses that are too late and outcomes that are far worse than our level of spending should deliver. In recent years, U.S. life expectancy has been declining. Fundamental to realizing better health, and a more effective health care system, is advancing the disruptive thinking that has spawned innovation in Silicon Valley and throughout the world. That's exactly what Stanford Medicine has done by proposing a new vision for health and health care. In Discovering Precision Health, Lloyd Minor and Matthew Rees describe a holistic approach that will set health care on the right track: keep people healthy by preventing disease before it starts and personalize the treatment of individuals precisely, based on their specific profile. With descriptions of the pioneering work undertaken at Stanford Medicine, complemented by fascinating case studies of innovations from entities including the Chan Zuckerberg Biohub, GRAIL, and Impossible Foods, Minor and Rees present a dynamic vision for the future of individual health and health care. Youll see how tools from smartphone technology to genome sequencing to routine blood tests are helping avert illness and promote health. And you'll learn about the promising progress already underway in bringing greater precision to the process of predicting, preventing, and treating a range of conditions, including allergies, mental illness, preterm birth, cancer, stroke, and autism. The book highlights how biomedical advances are dramatically improving our ability to treat and cure complex diseases, while emphasizing the need to devote more attention to social, behavioral, and environmental factors that are often the primary determinants of health. The authors explore thought-provoking topics including: The unlikely role of Google Glass in treating autism How gene editing can advance precision in treating disease What medicine can learn from aviation liHow digital tools can contribute to health and innovation Discovering Precision Health showcases entirely new ways of thinking about health and health care and can help empower us to lead healthier lives.

As Gods
As Gods

Author: Matthew Cobb

Publisher: Basic Books

Published: 2022-11-15

Total Pages: 502

ISBN-13: 1541602846

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The thrilling and terrifying history of genetic engineering In 2018, scientists manipulated the DNA of human babies for the first time. As biologist and historian Matthew Cobb shows in As Gods, this achievement was one many scientists have feared from the start of the genetic age. Four times in the last fifty years, geneticists, frightened by their own technology, have called a temporary halt to their experiments. They ought to be frightened: Now we have powers that can target the extinction of pests, change our own genes, or create dangerous new versions of diseases in an attempt to prevent future pandemics. Both awe-inspiring and chilling, As Gods traces the history of genetic engineering, showing that this revolutionary technology is far too important to be left to the scientists. They have the power to change life itself, but should we trust them to keep their ingenuity from producing a hellish reality?

Emperor Of Enzymes: A Biography Of Arthur Kornberg, Biochemist And Nobel Laureate
Emperor Of Enzymes: A Biography Of Arthur Kornberg, Biochemist And Nobel Laureate

Author: Errol C Friedberg

Publisher: World Scientific

Published: 2016-05-18

Total Pages: 338

ISBN-13: 9814699837

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This book chronicles the life and work of the late Arthur Kornberg, one of the premier biochemists in the world, who discovered the enzyme DNA polymerase, a key enzyme required for the biosynthesis of DNA.The book provides readers with a view of the personality and character of one of the great biochemists of the late 20th century, as well as insights into the origin and growth of the discipline of nucleic acid biochemistry, especially the biosynthesis of DNA.The book consists of 17 chapters that trace the life and work of Arthur Kornberg.

Landmark Cases in Intellectual Property Law
Landmark Cases in Intellectual Property Law

Author: Jose Bellido

Publisher: Bloomsbury Publishing

Published: 2017-09-07

Total Pages: 411

ISBN-13: 1509904689

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This volume explores the nature of intellectual property law by looking at particular disputes. All the cases gathered here aim to show the versatile and unstable character of a discipline still searching for landmarks. Each contribution offers an opportunity to raise questions about the narratives that have shaped the discipline throughout its short but profound history. The volume begins by revisiting patent litigation to consider the impact of the Statute of Monopolies (1624). It continues looking at different controversies to describe how the existence of an author's right in literary property was a plausible basis for legal argument, even though no statute expressly mentioned authors' rights before the Statute of Anne (1710). The collection also explores different moments of historical significance for intellectual property law: the first trade mark injunctions; the difficulties the law faced when protecting maps; and the origins of originality in copyright law. Similarly, it considers the different ways of interpreting patent claims in the late nineteenth and twentieth century; the impact of seminal cases on passing off and the law of confidentiality; and more generally, the construction of intellectual property law and its branches in their interaction with new technologies and marketing developments. It is essential reading for anyone interested in the development of intellectual property law.

The Gene
The Gene

Author: Siddhartha Mukherjee

Publisher: Simon and Schuster

Published: 2016-05-17

Total Pages: 624

ISBN-13: 1476733538

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The #1 NEW YORK TIMES Bestseller The basis for the PBS Ken Burns Documentary The Gene: An Intimate History Now includes an excerpt from Siddhartha Mukherjee’s new book Song of the Cell! From the Pulitzer Prize–winning author of The Emperor of All Maladies—a fascinating history of the gene and “a magisterial account of how human minds have laboriously, ingeniously picked apart what makes us tick” (Elle). “Sid Mukherjee has the uncanny ability to bring together science, history, and the future in a way that is understandable and riveting, guiding us through both time and the mystery of life itself.” —Ken Burns “Dr. Siddhartha Mukherjee dazzled readers with his Pulitzer Prize-winning The Emperor of All Maladies in 2010. That achievement was evidently just a warm-up for his virtuoso performance in The Gene: An Intimate History, in which he braids science, history, and memoir into an epic with all the range and biblical thunder of Paradise Lost” (The New York Times). In this biography Mukherjee brings to life the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices. “Mukherjee expresses abstract intellectual ideas through emotional stories…[and] swaddles his medical rigor with rhapsodic tenderness, surprising vulnerability, and occasional flashes of pure poetry” (The Washington Post). Throughout, the story of Mukherjee’s own family—with its tragic and bewildering history of mental illness—reminds us of the questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In riveting and dramatic prose, he describes the centuries of research and experimentation—from Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Morgan to Crick, Watson and Franklin, all the way through the revolutionary twenty-first century innovators who mapped the human genome. “A fascinating and often sobering history of how humans came to understand the roles of genes in making us who we are—and what our manipulation of those genes might mean for our future” (Milwaukee Journal-Sentinel), The Gene is the revelatory and magisterial history of a scientific idea coming to life, the most crucial science of our time, intimately explained by a master. “The Gene is a book we all should read” (USA TODAY).