Human Herpesviruses
Human Herpesviruses

Author: Yasushi Kawaguchi

Publisher: Springer

Published: 2018-06-12

Total Pages: 498

ISBN-13: 9811072302

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This book introduces and reviews several topics for each human herpesvirus. One of the most important features of the book is that it covers aspects of both basic research and clinical medicine. Herpesviridae, a family of double-strand DNA viruses, has unique biological features by which these viruses establish latency after primary infection and reactivate in later life. Nine human herpesviruses are known so far, and each of them causes a variety of diseases in both primary infection and reactivation. Since the discovery of each human herpesvirus, an abundance of findings related to them has accumulated in basic research and clinical medicine. However, the vast majority of biological features is still masked in mystery. Furthermore, a strategy of treatment and prevention has not yet been established for most human herpesviruses. A wide range of readers will be interested in this volume with its treatment of problematic points and latest findings in the field.

Geotechnical Design for Sublevel Open Stoping
Geotechnical Design for Sublevel Open Stoping

Author: Ernesto Villaescusa

Publisher: CRC Press

Published: 2014-04-01

Total Pages: 546

ISBN-13: 1482211882

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The first comprehensive work on one of the most important underground mining methods worldwide, Geotechnical Design for Sublevel Open Stoping presents topics according to the conventional sublevel stoping process used by most mining houses, in which a sublevel stoping geometry is chosen for a particular mining method, equipment availability, and work force experience. Summarizing state-of-the-art practices encountered during his 25+ years of experience at industry-leading underground mines, the author: Covers the design and operation of sublevel open stoping, including variants such as bench stoping Discusses increases in sublevel spacing due to advances in the drilling of longer and accurate production holes, as well as advances in explosive types, charges, and initiation systems Considers improvements in slot rising through vertical crater retreat, inverse drop rise, and raise boring Devotes a chapter to rock mass characterization, since increases in sublevel spacing have meant that larger, unsupported stope walls must stand without collapsing Describes methodologies to design optimum open spans and pillars, rock reinforcement of development access and stope walls, and fill masses to support the resulting stope voids Reviews the sequencing of stoping blocks to minimize in situ stress concentrations Examines dilution control action plans and techniques to back-analyze and optimize stope wall performance Featuring numerous case studies from the world-renowned Mount Isa Mines and examples from underground mines in Western Australia, Geotechnical Design for Sublevel Open Stoping is both a practical reference for industry and a specialized textbook for advanced undergraduate and postgraduate mining studies.

Epstein Barr Virus Volume 2
Epstein Barr Virus Volume 2

Author: Christian Münz

Publisher: Springer

Published: 2015-10-01

Total Pages: 493

ISBN-13: 331922834X

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Epstein Barr virus (EBV) was discovered as the first human tumor virus around 50 years ago. Since its discovery in Burkitt’s lymphoma it has been associated with various other malignancies, infectious mononucleosis and even autoimmune diseases. The two book volumes on EBV summarize the first 50 years of research on this tumor virus, starting with historical perspectives on discovery, oncogenicity and immune control, reviewing the role that the virus plays in the various associated diseases and concluding with a discussion on how the immune system keeps persistent EBV infection under control in healthy EBV carriers and can be used to treat EBV associated diseases. The respective 32 chapters are written by international experts from three continents for health care providers, biomedical researchers and patients that are affected by EBV. The assembled knowledge should help to understand EBV associated diseases better and to develop EBV specific vaccination in the near future.

Human Oncogenic Viruses
Human Oncogenic Viruses

Author: Jing-hsiung James Ou

Publisher: World Scientific

Published: 2010

Total Pages: 354

ISBN-13: 9812833471

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Viruses are the causes of approximately 25% of human cancers. Due to their importance in carcinogenesis, there is a desperate need for a book that discusses these viruses. This book is therefore timely, providing a comprehensive review of the molecular biology of oncogenic viruses and the cancers they cause. Viruses that are discussed in the individual chapters include hepatitis B virus, hepatitis C virus, human papilloma viruses, EpsteinOCoBarr virus, Kaposi's sarcoma virus and human T-cell leukemia virus type 1. This book provides up-to-date information for graduate students, postdoctoral fellows, medical students, physicians and non-experts who are interested in learning more about the oncogenic viruses and how they cause human cancers. Sample Chapter(s). Foreword (38 KB). Chapter 1: Oncogenic Viruses, Cellular Transformation and Human Cancers (211 KB). Contents: Oncogenic Viruses, Cellular Transformation and Human Cancers (Y-Y Zheng & J-H J Ou); Hepatitis B Virus and Hepatocellular Carcinogenesis (T S B Yen); Molecular Mechanism of Hepatitis C Virus Carcinogenesis (K Machida et al.); Human Papillomaviruses and Associated Malignancies (C L Nguyen et al.); Epstein-Barr Virus and Its Oncogenesis (H-P Li et al.); Human Kaposi's Sarcoma-associated Herpesvirus: Molecular Biology and Oncogenesis (P J Dillon & B Damania); Human T-Cell Leukemia Virus 1 and Cellular Transformation (Y-H Chi & K-T Jeang). Readership: Graduate students and postdoctoral fellows in infectious diseases, microbiology/virology, oncology/cancer research, and cell/molecular/structural biology; medical students, physicians and non-experts who are interested in understanding the relationship between oncogenic viruses and the cancers they cause