A Tale of Two Viruses
A Tale of Two Viruses

Author: Neeraja Sankaran

Publisher: University of Pittsburgh Press

Published: 2021-03-09

Total Pages: 410

ISBN-13: 0822987716

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In 1965, French microbiologist André Lwoff was awarded the Nobel Prize in Physiology or Medicine for his work on lysogeny—one of the two types of viral life cycles—which resolved a contentious debate among scientists about the nature of viruses. A Tale of Two Viruses is the first study of medical virology to compare the history of two groups of medically important viruses—bacteriophages, which infect bacteria, and sarcoma agents, which cause cancer—and the importance of Lwoff’s discovery to our modern understanding of what a virus is. Although these two groups of viruses may at first glance appear to have little in common, they share uniquely parallel histories. The lysogenic cycle, unlike the lytic, enables viruses to replicate in the host cell without destroying it and to remain dormant in a cell’s genetic material indefinitely, or until induced by UV radiation. But until Lwoff’s discovery of the mechanism of lysogeny, microbiologist Félix d’Herelle and pathologist Peyton Rous, who themselves first discovered and argued for the viral identity of bacteriophages and certain types of cancer, respectively, faced opposition from contemporary researchers who would not accept their findings. By following the research trajectories of the two virus groups, Sankaran takes a novel approach to the history of the development of the field of medical virology, considering both the flux in scientific concepts over time and the broader scientific landscapes or styles that shaped those ideas and practices.

SARS, MERS and other Viral Lung Infections
SARS, MERS and other Viral Lung Infections

Author: David S. Hui

Publisher: European Respiratory Society

Published: 2016-06-01

Total Pages: 148

ISBN-13: 1849840709

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Viral respiratory tract infections are important and common causes of morbidity and mortality worldwide. In the past two decades, several novel viral respiratory infections have emerged with epidemic potential that threaten global health security. This Monograph aims to provide an up-to-date and comprehensive overview of severe acute respiratory syndrome, Middle East respiratory syndrome and other viral respiratory infections, including seasonal influenza, avian influenza, respiratory syncytial virus and human rhinovirus, through six chapters written by authoritative experts from around the globe.

Essentials of Glycobiology
Essentials of Glycobiology

Author: Ajit Varki

Publisher: CSHL Press

Published: 1999

Total Pages: 694

ISBN-13: 9780879696818

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Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.

Examining Viruses and Bacteria
Examining Viruses and Bacteria

Author: Louise Eaton

Publisher: Encyclopaedia Britannica

Published: 2017-12-15

Total Pages: 221

ISBN-13: 1538300044

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Bacteria and viruses are among the oldest agents on Earth and reveal much about the planet's past and evolution. As scientists and doctors make progress in fighting the harmful effects of bacteria and viruses, they also often make discoveries that can lead to life-saving vaccines and antibiotics, making the fields of microbiology and biochemistry more intriguing and challenging than ever. In this volume, readers will venture into the realm of bacteria and viruses to explore these constantly changing agents and the roles they play in nature, medicine, and disease.

Bacteriophage Ecology
Bacteriophage Ecology

Author: Stephen T. Abedon

Publisher: Cambridge University Press

Published: 2008-05-01

Total Pages: 457

ISBN-13: 1139471945

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Bacteriophages, or phages, are viruses that infect bacteria and are believed to be the most abundant and genetically diverse organisms on Earth. As such, their ecology is vast both in quantitative and qualitative terms. Their abundance makes an understanding of phage ecology increasingly relevant to bacterial ecosystem ecology, bacterial genomics and bacterial pathology. Abedon provides the first text on phage ecology for almost 20 years. Written by leading experts, synthesizing the three key approaches to studying phage ecology, namely studying them in natural environments (in situ), experimentally in the lab, or theoretically using mathematical or computer models. With strong emphasis on microbial population biology and distilling cutting-edge research into basic principles, this book will complement other currently available volumes. It will therefore serve as an essential resource for graduate students and researchers, particularly those with an interest in phage ecology and evolutionary biology.

Viruses, Bacteria and Fungi in the Built Environment
Viruses, Bacteria and Fungi in the Built Environment

Author: F. Pacheco-Torgal

Publisher: Woodhead Publishing

Published: 2021-12-02

Total Pages: 350

ISBN-13: 0323852211

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Viruses, Bacteria and Fungi in the Built Environment: Designing Healthy Indoor Environments opens with a brief introduction to viruses, bacteria and fungi in the built environment and discusses their impact on human health. Sections discuss the microbiology of building materials, the airborne transmission of viruses and bacteria in the built environment, and plumbing-associated microbiome. As the first book on this important area to be written in light of the COVID-19 pandemic, this work will be a valuable reference resource for researchers, civil engineers, architects, postgraduate students, contractors and other professionals working and interested in the field of the built environment. Elements of building design, including choice of materials, ventilation and plumbing can have important implications for the microbiology of a building, and consequently, the health of the building's occupants. This important new reference work explains the microbiology of buildings and disease control in the built environment to those who design and implement new construction and renovate. - Provides an essential guide on the microbiology of buildings, covering bacteria, fungi and viruses on surfaces, in air and in water - Comprehensively examines how humidity influences fungal growth in several building materials - Includes important information about the airborne transmission of infectious agents - Addresses ventilation design to improve human health - Presents the first book on disease control in buildings since the COVID-19 pandemic

Virus Structure
Virus Structure

Author:

Publisher: Elsevier

Published: 2003-10-02

Total Pages: 610

ISBN-13: 0080493777

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Virus Structure covers the full spectrum of modern structural virology. Its goal is to describe the means for defining moderate to high resolution structures and the basic principles that have emerged from these studies. Among the topics covered are Hybrid Vigor, Structural Folds of Viral Proteins, Virus Particle Dynamics, Viral Gemone Organization, Enveloped Viruses and Large Viruses. - Covers viral assembly using heterologous expression systems and cell extracts - Discusses molecular mechanisms in bacteriophage T7 procapsid assembly, maturation and DNA containment - Includes information on structural studies on antibody/virus complexes