Automation: Genomic and Functional Analyses

Automation: Genomic and Functional Analyses

Author: Alister G. Craig

Publisher: Elsevier

Published: 1999-02

Total Pages: 296

ISBN-13: 9780121948603

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Evaluation and functional analysis, to provide insight into this "new age" of research based on genomic and chemical screening. Key Features * Describes automated procedures used in microbiology and molecular biology * Includes developments in robotics and vision systems * Features automation in library picking, presentation and analysis * Discusses paralogous duplications in microbial genomes * Covers deciphering genomes through automated large-scale sequencing * Describes and stresses the need for functional analyses * Internationally acclaimed contributors, including Professor Leroy Hood.


Yeast Gene Analysis

Yeast Gene Analysis

Author:

Publisher: Elsevier

Published: 2011-09-21

Total Pages: 731

ISBN-13: 0080521789

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Focusing on Saccharomyces cerevisiae, the second edition of Yeast Gene Analysis represents a major reworking of the original edition, with many completely new chapters and major revisions to all previous chapters. Originally published shortly after completion of the yeast genome sequence, the new edition covers many of the major genome-wide strategies that have been developed since then such as microarray analysis of transcription, synthetic gene array studies, protein microarrays and chemical genetic approaches. It represents a valuable resource for any research laboratory using budding yeast as their experimental system in which to identify new yeast gene functions. The chapters are written in a readable style with useful background information, technical tips and specific experimental protocols included as appropriate, enabling both the novice and the experienced yeast researcher to adopt new procedures with confidence. - New chapters on: Strain construction; genome-wide two-hybrid approaches; use of microarrays for transcript analysis; real-time analysis of chromosome behaviour and FRET; synthetic gene array technology and protein arrays; chemical genomics and yeast prions; RNA gene analysis and mitochondrial gene function analysis; phylogenetic footprinting; discovering human gene function and predicting yeast gene function


Measuring Biological Responses with Automated Microscopy

Measuring Biological Responses with Automated Microscopy

Author:

Publisher: Elsevier

Published: 2006-11-02

Total Pages: 736

ISBN-13: 0080468985

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The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today-truly an essential publication for researchers in all fields of life sciences.


Forensic DNA Typing

Forensic DNA Typing

Author: John Marshall Butler

Publisher: Academic Press

Published: 2001

Total Pages: 340

ISBN-13: 9780121479510

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This comprehensive handbook offers crime laboratory personnel, investigators and members of the legal community the latest information on STR typing. It covers new genetic markers and information on rapidly changing technologies to help professionals accurately identify the perpetrators of crimes -- or those falsely accused of a crime -- when DNA samples are available.


Encyclopedia of Genetics, Genomics, Proteomics, and Informatics

Encyclopedia of Genetics, Genomics, Proteomics, and Informatics

Author: George P. Rédei

Publisher: Springer Science & Business Media

Published: 2008-04-25

Total Pages: 2139

ISBN-13: 1402067534

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This new third edition updates a best-selling encyclopedia. It includes about 56% more words than the 1,392-page second edition of 2003. The number of illustrations increased to almost 2,000 and their quality has improved by design and four colors. It includes approximately 1,800 current databases and web servers. This encyclopedia covers the basics and the latest in genomics, proteomics, genetic engineering, small RNAs, transcription factories, chromosome territories, stem cells, genetic networks, epigenetics, prions, hereditary diseases, and patents. Similar integrated information is not available in textbooks or on the Internet.


Progress in Immunology Research

Progress in Immunology Research

Author: Barbara A. Veskler

Publisher: Nova Publishers

Published: 2005

Total Pages: 274

ISBN-13: 9781594543807

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Immunology is the study of the body's protection from foreign macromolecules or invading organisms and the responses to them. These invaders include viruses, bacteria, protozoa or even larger parasites. In addition, immune responses are developed against our own proteins (and other molecules) in autoimmunity and against our own aberrant cells in tumour immunity. The first line of defence against foreign organisms are barrier tissues such as the skin that stop the entry of organism into our bodies. A second line of defence is the specific or adaptive immune system which may take days to respond to a primary invasion (that is infection by an organism that has not hitherto been seen). This new book brings together new research from around the globe dealing with this extremely important subject.


Protein Structure

Protein Structure

Author: Daniel Chasman

Publisher: CRC Press

Published: 2003-03-18

Total Pages: 634

ISBN-13: 9780203911327

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This text offers in-depth perspectives on every aspect of protein structure identification, assessment, characterization, and utilization, for a clear understanding of the diversity of protein shapes, variations in protein function, and structure-based drug design. The authors cover numerous high-throughput technologies as well as computational met


Focus on Genome Research

Focus on Genome Research

Author: Clyde R. Williams

Publisher: Nova Publishers

Published: 2004

Total Pages: 442

ISBN-13: 9781590339602

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The genomic approach of technology development and large-scale generation of community resource data sets has introduced an important new dimension in biological and biomedical research. Interwoven advances in genetics, comparative genomics, high throughput biochemistry and bioinformatics are combining to attack basic understanding of human life and disease and to develop strategies to combat disease. Genomic Research began with The Human Genome Project (HGP), the international research effort that determined the DNA sequence of the entire human genome, completed in April 2003. The HGP also included efforts to characterize and sequence the entire genomes of several other organisms, many of which are used extensively in biological research. Identification of the sequence or function of genes in a model organism is an important approach to finding and elucidating the function of human genes. Integral to the HGP are similar efforts to understand the genomes of various organisms commonly used in biomedical research, such as mice, fruit flies and roundworms. Such organisms are called "model organisms," because they can often serve as research models for how the human organism behaves. This new book brings together leading research from throughout the world in this cutting-edge field.