Conquering Lyme Disease

Conquering Lyme Disease

Author: Brian A. Fallon

Publisher: Columbia University Press

Published: 2017-12-12

Total Pages: 608

ISBN-13: 0231545185

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Lyme disease is the most common tick-borne illness in the United States, with more than 300,000 cases diagnosed each year. However, doctors are deeply divided on how to diagnose and treat it, giving rise to the controversy known as the “Lyme Wars.” Firmly entrenched camps have emerged, causing physicians, patient communities, and insurance providers to be pitted against one another in a struggle to define Lyme disease and its clinical challenges. Health care providers may not be aware of its diverse manifestations or the limitations of diagnostic tests. Meanwhile, patients have felt dismissed by their doctors and confused by the conflicting opinions and dubious self-help information found online. In this authoritative book, the Columbia University Medical Center physicians Brian A. Fallon and Jennifer Sotsky explain that, despite the vexing “Lyme Wars,” there is cause for both doctors and patients to be optimistic. The past decade’s advances in precision medicine and biotechnology are reshaping our understanding of Lyme disease and accelerating the discovery of new tools to diagnose and treat it, such that the great divide previously separating medical communities is now being bridged. Drawing on both extensive clinical experience and cutting-edge research, Fallon, Sotsky, and their colleagues present these paradigm-shifting breakthroughs in language accessible to both sides. They clearly explain the immunologic, infectious, and neurologic basis of chronic symptoms, the cognitive and psychological impact of the disease, as well as current and emerging diagnostic tests, treatments, and prevention strategies. Written for the educated patient and health care provider seeking to learn more, Conquering Lyme Disease gives an up-to-the-minute overview of the science that is transforming the way we address this complex illness. It argues forcefully that the expanding plague of Lyme and other tick-borne diseases can be confronted successfully and may soon even be reversed.


Aspects of Lyme Borreliosis

Aspects of Lyme Borreliosis

Author: G. Schierz

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 667

ISBN-13: 3642776140

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Aspects of Lyme Borreliosis is a comprehensive scientific presentation of virtually all aspects of lyme borreliosis. It starts with a concise history of lyme borreliosis and its causative agent, Borrelia burgdorferi. The morphological and biological characteristics of B. burgdorferi are presented, followed by outlines on the ecology and histopathology of LB.The various aspects of the clinical manifestations of LB are systematically dealt with, starting with a clinical overview. A special chapter covers the microbiological diagnosis. After a presentation on the susceptibility of B. burgdorferi in vitro and in animals against a great variety of antibiotics, a thorough discussion on the treatment of LB including criticalremarks follows. The book closes with a chapter on the epidemiology of LB.


Emerging Infectious Uveitis

Emerging Infectious Uveitis

Author: Soon-Phaik Chee

Publisher: Springer

Published: 2017-05-31

Total Pages: 196

ISBN-13: 3319234161

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This book reviews the various emerging infectious diseases that show a significant association with uveitis, describing and explaining their ocular manifestations with the aid of color illustrations. In addition, it presents brief reports of further emerging infections that are associated with uveitis in rare cases. The coverage is wide ranging, encompassing diverse emerging bacterial, viral, parasitic and fungal infections. Individual chapters are also devoted to important re-emergent diseases such as syphilis and tuberculosis, with the focus on new data on epidemiology, diagnosis and management. Emerging infectious diseases are defined as “those whose incidence in humans has increased within the past two decades or threatens to increase in the near future”. Emergence may be due to the spread of a new agent, to the recognition of an infection that has been present in the population but has gone undetected, or to the realization that an established disease has an infectious origin. This book will be an invaluable source of information on all aspects of uveitis in these diseases.


Rickettsial Diseases

Rickettsial Diseases

Author: Didier Raoult

Publisher: CRC Press

Published: 2007-04-26

Total Pages: 400

ISBN-13: 142001997X

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The only available reference to comprehensively discuss the common and unusual types of rickettsiosis in over twenty years, this book will offer the reader a full review on the bacteriology, transmission, and pathophysiology of these conditions. Written from experts in the field from Europe, USA, Africa, and Asia, specialists analyze specific patho


Lyme Borreliosis in Europe and North America

Lyme Borreliosis in Europe and North America

Author: Sunil K. Sood

Publisher: John Wiley & Sons

Published: 2011-04-18

Total Pages: 280

ISBN-13: 047093395X

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The facts about Lyme disease, from epidemiology to treatment to control Lyme borreliosis, popularly known as Lyme disease, remains the most commonly reported tick-transmitted infection in North America and Europe. A growing body of scientific and clinical evidence has facilitated early diagnosis and effective treatment. Nonetheless, there are a number of misconceptions about this infectious disease that have given rise to unproven, potentially dangerous alternative therapies. In Lyme Borreliosis in Europe and North America, a team of authors whose expertise spans basic research, epidemiology, and clinical practice has compiled evidence-based information on Lyme borreliosis. Presents all the latest evidence needed to diagnose, treat, and prevent Lyme disease Lyme Borreliosis in Europe and North America begins with a review of the disease's epidemiology, the causative Borrelia genospecies, and tick vectors. It then explores pathogenesis, diagnosis, and treatment. Next, the book examines the role of serologic, culture, and molecular diagnostic methods. The book also features a chapter on prognosis, offering an evidence-based review of outcome studies, as well as practical advice to physicians to help them manage the challenging clinical scenario of chronic symptoms attributed to Borrelia infection. The final chapter is a guide to prevention strategies, including the management of tick bites. Examines similarities and differences in Europe and North America Because differences in Borrelia genospecies are responsible for differences in the clinical presentation of Lyme borreliosis between North America and Europe, this book provides descriptions of the disease as it presents on each continent. Most of the chapters have been cowritten by experts on each continent, in order to provide a balanced perspective that combines European and North American findings, practices, and experiences. Helps everyone better understand, treat, and control Lyme disease Lyme Borreliosis in Europe and North America is a comprehensive reference, ideal for clinicians, researchers, and public health officials who seek to treat and control Lyme borreliosis. It will help them better understand the facts and make sense of the misconceptions and myths that surround this infectious disease.


Granulomatous diseases in Otorhinolaryngology, Head and Neck

Granulomatous diseases in Otorhinolaryngology, Head and Neck

Author: Sanjana Vijay Nemade

Publisher: Springer Nature

Published: 2021-09-09

Total Pages: 329

ISBN-13: 9811640475

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This book provides the description of the granulomatous diseases of otorhinolaryngology, head and neck with their characteristic features, investigations and management. It includes wide variety of infective, idiopathic, neoplastic, hereditary, reactive and various other types of chronic granulomatous reaction in the ear, nose, throat and head neck region. Further, the description is supported with various illustrations including clinical photographs, radiological pictures of CT scan, MRI scan etc. Histopathological and microbiological images which show characteristics and differentiating features are also included to aid in the diagnosis of the diseases. Histopathological colored images with high magnification and immunohistochemistry images are provided for better illustrations. This book also elaborates the important medical and surgical management of the granulomatous diseases. Every chapter ends with the ‘Essential features’ of that particular granulomatous disease, and this will certainly help the post-grad students and clinicians to differentiate the diseases, early diagnosis and management of the patients with chronic granulomatous diseases.


Lyme Disease and Relapsing Fever Spirochetes

Lyme Disease and Relapsing Fever Spirochetes

Author: Justin D Radolf

Publisher:

Published: 2021

Total Pages: 770

ISBN-13: 9781913652616

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Lyme disease (Lyme borreliosis) is the most prevalent vector-borne illness in the United States and Europe and a growing threat to global health. In addition Lyme disease is considered a model system of emerging infectious diseases. The book Borrelia: Molecular Biology, Host Interaction and Pathogenesis published in 2010 was the first state-of-the-art reference work covering the myriad, interlaced facets of the enzootic disorders caused by pathogenic Borrelia. This current volume, by the same editors, builds on the previous work and contains a vast amount of new information, a wider scope, and increased coverage of genomics, genetics, evolutionary biology, vector biology, physiology, pathogenicity, immune response, and immune evasion. Written by renowned scientists who have made seminal contributions to the field, this book contains an expansive treatment of the options to track live spirochetes and evaluate gene expression in ticks and mice, provides insights into the workings of the flagellar motor, presents up-to-date research on the modulation of gene expression, and reviews recent studies on the Lyme disease spirochete's networks of regulatory pathways. The volume highlights and describes in detail the tremendous advances in understanding of the Borrelia genus at the molecular and cellular levels as well as the pathogenesis of Lyme disease and relapsing fever. This comprehensive volume is indispensable for anyone involved in Borrelia and Lyme disease research and is highly recommended for microbiologists, immunologists, and physicians with an interest in spirochetes, vector-borne illness, or emerging infectious diseases. The book is a recommended reference volume for all microbiology libraries.


Neuroinfections

Neuroinfections

Author: Don Gilden

Publisher: Oxford University Press

Published: 2013-05-02

Total Pages: 205

ISBN-13: 0199926638

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Neuroinfections provides real-time case descriptions of 19 neurologic diseases produced by virus, as well as bacterial meningitis and other infections produced by spirochetes, protozoans and prions, as well as inflammatory diseases of the nervous system of unknown etiology.


The Lyme Disease Solution

The Lyme Disease Solution

Author: Kenneth B. Singleton

Publisher: Brown Books

Published: 2008

Total Pages: 523

ISBN-13: 9781934812006

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Lyme disease has become the fastest-growing infectious disease transmitted by ticks (or other vectors) in the United States, but still remains a condition that is frequently misunderstood, overlooked, and misdiagnosed. Written by a leading practitioner of Lyme-aware medicine, this comprehensive guide will reveal to you the facts about this very serious disease - symptoms of which can mimic cardiac, neurological, and rheumatoid conditions - and will tell you what you need to know about the diagnosis, treatment, and prevention of Lyme disease.