Comprehensive Medicinal Chemistry III

Comprehensive Medicinal Chemistry III

Author:

Publisher: Elsevier

Published: 2017-06-03

Total Pages: 4609

ISBN-13: 0128032014

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Comprehensive Medicinal Chemistry III, Eight Volume Set provides a contemporary and forward-looking critical analysis and summary of recent developments, emerging trends, and recently identified new areas where medicinal chemistry is having an impact. The discipline of medicinal chemistry continues to evolve as it adapts to new opportunities and strives to solve new challenges. These include drug targeting, biomolecular therapeutics, development of chemical biology tools, data collection and analysis, in silico models as predictors for biological properties, identification and validation of new targets, approaches to quantify target engagement, new methods for synthesis of drug candidates such as green chemistry, development of novel scaffolds for drug discovery, and the role of regulatory agencies in drug discovery. Reviews the strategies, technologies, principles, and applications of modern medicinal chemistry Provides a global and current perspective of today's drug discovery process and discusses the major therapeutic classes and targets Includes a unique collection of case studies and personal assays reviewing the discovery and development of key drugs


Biomedical Chemistry

Biomedical Chemistry

Author: Nuno Vale

Publisher: Walter de Gruyter GmbH & Co KG

Published: 2015-01-01

Total Pages: 361

ISBN-13: 3110468751

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Biomedical Chemistry provides readers with an understanding of how fundamental chemical concepts are used to combat some diseases. The authors explain the interdisciplinary relationship of chemistry with biology, physics, pharmacy and medicine. The results of chemical research can be applied to understand chemical processes in cells and in the body, and new methods for drug transportation. Also, basic chemical ideas and determination of disease etiology are approached by developing techniques to ensure optimum interaction between drugs and human cells. This Book is an excellent resource for students and researchers in health-related fields with frontier topics in medicinal and pharmaceutical chemistry, organic chemistry and biochemistry.


From Medical Chemistry to Biochemistry

From Medical Chemistry to Biochemistry

Author: Robert E. Kohler

Publisher: Cambridge University Press

Published: 1982-05-31

Total Pages: 426

ISBN-13: 9780521243124

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This penetrating case study of institution building and entrepreneurship in science shows how a minor medical speciality evolved into a large and powerful academic discipline. Drawing extensively on little-used archival sources, the author analyses in detail how biomedical science became a central part of medical training and practice. The book shows how biochemistry was defined as a distinct discipline by the programmatic vision of individual biochemists and of patrons and competitors in related disciplines. It shows how discipline builders used research programmes as strategies that they adapted to the opportunities offered by changing educational markets and national medical reform movements in the United States, Britain and Germany. The author argues that the priorities and styles of various departments and schools of biochemistry reflect systematic social relationships between that discipline and biology, chemistry and medicine. Science is shaped by its service roles in particular local contexts: This is the central theme. The author's view of the political economy of modern science will be of interest to historians and social scientists, scientific and medical practitioners, and anyone interested in the ecology of knowledge in scientific institutions and professions.


Biomedical Chemistry

Biomedical Chemistry

Author: Paul F. Torrence

Publisher: John Wiley & Sons

Published: 2000-01-24

Total Pages: 438

ISBN-13: 9780471326335

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How basic chemical ideas help advance the understanding and treatment of disease Biomedical Chemistry presents clear, concise coverage of the application of chemistry to drug discovery and determination of disease etiology, highlighting its role in the explosive growth of biotechnology and molecular biology. Through expert contributions from leading researchers in diverse fields, the book provides readers with an understanding of how fundamental chemical concepts are used in the development of novel approaches to the major problems in medicine today. The authors explain both the science and reasoning underlying each experimental approach, exploring cutting-edge developments in AIDS, cancer, alcoholism, Parkinson's disease, trypanosomiasis, emphysema, and malaria. Contemporary research problems discussed include: * Mechanism-based drug discovery * Design of new antitumor and antiviral agents * Targeting tumors using magnetic drug delivery * Antisense and antigene agents Easily accessible to anyone with a solid undergraduate background in chemistry, Biomedical Chemistry is an excellent resource for researchers in health-related fields as well as anyone seeking an overview of frontier topics in medicinal chemistry, organic chemistry, and biochemistry.


Journal

Journal

Author: Missouri State Medical Association

Publisher:

Published: 1911

Total Pages: 452

ISBN-13:

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Applied Radiation Chemistry

Applied Radiation Chemistry

Author: Robert J. Woods

Publisher: John Wiley & Sons

Published: 1993-12-16

Total Pages: 572

ISBN-13: 9780471544524

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Deals with radiation processing as a whole using a chemical perspective. Offers basic information on the procedures taking place and covers radiation dosimetry plus a wide range of actual and potential applications. Provides excellent coverage of radiation processing literature with bibliographies pertaining to key areas of radiation chemistry.