Clinical application of antithrombotic therapy in both arterial disease (acute coronary syndromes, acute MI, peripheral arterial disease, valvular heart disease, atrial fibrillation) and venous disease, (venous thromboembolic disease and pulmonary embolism). Results of major clinical trials and their implications for clinical practice.
An essential companion for busy professionals seeking to navigate stroke-related clinical situations successfully and make quick informed treatment decisions.
Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.
This book presents the latest evidence and guidelines supporting the use of anticoagulant therapy for various clinical scenarios. The field of anticoagulation therapy is evolving rapidly, particularly since the arrival and widespread adoption of direct oral anticoagulants. Organized in two parts, this book reviews the pharmacologic properties of various anticoagulants and details the clinical applications of anticoagulant therapy. Drugs such as warfarin and unfractionated heparin, as well as parenteral and direct oral anticoagulants are discussed in terms of their pharmacokinetics, drug-disease interactions, dosing strategies, and risk considerations. Clinical applications of anticoagulant therapy in disorders such as acute coronary syndromes, atrial fibrillation, and thrombophilia and in special populations such as pregnant women, the elderly, and in the patient with cancer are highlighted. Clinical vignettes, algorithms, clinical pearls, and self-assessment questions are integrated throughout the book. Featuring contributions from authorities in the field, Anticoagulation Therapy is an essential resource for cardiologists, vascular medicine specialists, hematologists, internists, and all other healthcare professionals who prescribe anticoagulants.
TRANSCATHETER MITRAL VALVE THERAPIES An essential survey of the advancing field of transcatheter mitral valve repair and replacement Minimally invasive transcatheter therapies have revolutionized the treatment of structural heart disease. Greatly improving outcomes for higher-risk patients, transcatheter aortic valve replacement is now established as a safe and effective alternative to invasive surgery. The mitral valve, however, poses further challenges. Contending with one of the heat’s most anatomically and pathologically complex components, practitioners and engineers have yet to perfect a stream-lined, widely deliverable therapy—though they are getting closer and closer to this goal. Transcatheter Mitral Valve Therapies provides a far-reaching survey of the field of mitral interventions in its current state. Highlighting the stumbling blocks preventing transcatheter mitral valve replacement’s widespread adoption, the book’s international group of contributors discuss the improvements to be made in repair and replacement procedures, as well as the adjunctive use of imaging and pharmacologic therapies. This ground-breaking text: Provides detailed explanations of transcatheter repair, transcatheter replacement, and adjunctive procedures Features chapters on the use of imaging to aid in patient selection, procedure planning, and intra-operative guidance Discusses the importance of minimally invasive approaches for mitral valve repair Examines anticoagulation following transcatheter mitral valve interventions Outlines the possible future of transcatheter mitral valve therapy Transcatheter Mitral Valve Therapies is an important, up-to-date resource for interventional cardiologists, as well as all clinical researchers and practitioners seeking information on this vital and developing treatment.
Showcasing the expertise of top-tier specialists who contributed to the newly released guidelines for the care of thrombosis in cancer patients, this exciting guide was written and edited by members of the American Society of Clinical Oncology panel, (ASCO), on the prevention and treatment of cancer-associated thrombosis, among others, and provides
Thoroughly revised, this handy manual is filled with practical advice for the entire cardiac care team. It covers all aspects of care of the surgical heart patient-from preoperative assessment to postoperative management to treatment protocols. Chapters written by both nurses and doctors emphasize the critical care team approach to cardiac surgery to improve patient outcomes and provide useful, practical information for every clinical setting. A logical organization, including individual sections on preoperative, operative, and postoperative issue speeds to the information you need. The latest details on coronary artery disease . fluid, electrolyte, and renal function . management of postoperative cardiac arrhythmias . mechanical devices . and postoperative myocardial ischemia enhance your clinical acumen. An updated appendix of Management Summaries keeps you current on the latest in care. New images and line drawings illuminate key steps to help you master every procedure.
Praise for the previous edition: "Extraordinary achievement … this volume stands on its own as a marvelous feat in bringing such a vast array of clear and coherent instruction to endoscopists at all skill levels."—Gastroenterology Written and edited by internationally renowned specialists, the third edition of Gastroenterological Endoscopy covers the entire spectrum of diagnostic and therapeutic procedures for the upper and lower GI tract while providing the latest overview of GI disorders. A great wealth of high-resolution photographs provides the visual information needed to confidently assess and diagnose mucosal lesions of the entire digestive tract. Significant advances in the field—both medical and technical—since the last edition are covered in comprehensive detail. Key Features: New panel of top international editors, continuing the tradition of excellence, depth, and breadth as originated by founding editors Classen, Tytgat, and Lightdale; list of contributing authors is a "who's who" of GI endoscopy Coverage of newest, advanced tools and techniques: gastric-POEMS, submucosal tunnel endoscopic resection (STER), lumen-apposing metal stents, "over-the-scope" clips, and much more More than 1,500 exquisite images Gastroenterological Endoscopy, third edition, surely deserves a prominent place in any complete endoscopy reference collection. Michael B. Wallace, MD, is Professor of Medicine at the Division of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, Florida, USA Paul Fockens, MD, is Professor and Chair of the Dept. of Gastroenterology and Hepatology at the Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands Joseph Jao-Yiu Sung, MD, PhD, is Mok Hing Yiu Professor of Medicine and Director of the Institute of Digestive Diseases of The Chinese University of Hong Kong, Shatin, Hong Kong An award-winning international medical and scientific publisher, Thieme has demonstrated its commitment to the highest standard of quality in the state-of-the-art content and presentation of all its products. Founded in 1886, the Thieme name has become synonymous with high quality and excellence in online and print publishing.
This book is open access under a CC BY 4.0 license. This quick-reference handbook offers a concise and practical review of key aspects of the treatment of ST-segment elevation myocardial infarction (STEMI) in the era of primary percutaneous coronary intervention (PPCI). In the context of STEMI, PPCI is the preferred mode of emergency revascularization. Access to PPCI is rapidly increasing and is now routinely practiced in both general and specialist hospitals and there has been a recent emphasis on developing STEMI networks to enhance and expedite the referral pathway. This coupled with concurrent developments to enhance the safety and efficacy of the PPCI procedure has heralded an era where STEMI interventions are increasingly considered an important subspecialty within interventional cardiology. Written by leading cardiologists who have been instrumental in the adoption of PPCI in their respective institutions, the book provides junior and senior cardiologists alike with insightful and thought-provoking tips and tricks to enhance the success of PPCI procedures, which may in turn translate into direct improvements in outcomes. The book is also relevant for healthcare providers and emergency department physicians.
Aimed specifically at general practitioners, this new addition to the series covers an important area of cardiovascular therapy. It discusses both the mechanisms of antithrombotic therapy and its uses for parents at risk, and will be a highly practical guide in primary care.