Antimicrobial Nanoarchitectonics

Antimicrobial Nanoarchitectonics

Author: Alexandru Mihai Grumezescu

Publisher: William Andrew

Published: 2017-06-22

Total Pages: 578

ISBN-13: 0323527345

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Antimicrobial Nanoarchitectonics: From Synthesis to Applications brings together recent research in antimicrobial nanoparticles, specifically in the sustained and controlled delivery of antimicrobials. Particular attention is given to i) reducing the side effects of antibiotics, ii) increasing the pharmacological effect, and iii) improving aqueous solubility and chemical stability of different antimicrobials. In addition, antimicrobial nanoparticles in drug delivery are discussed extensively. The book also evaluates the pros and cons of using nanostructured biomaterials in the prevention and eradication of infections. It is an important reference resource for materials scientists and bioengineers who want to learn how nanomaterials are used in antimicrobial therapy. - Provides readers with the information necessary to select the appropriate bionanomaterial to solve particular infection problems - Includes case studies, showing how particular bionanomaterials have been used to cure infections - Explains the central role that nanotechnology plays in modern antimicrobial therapy - Evaluates the pros and cons of using nanostructured biomaterials in the prevention and eradication of infections


Emerging Nanomaterials and Nano-based Drug Delivery Approaches to Combat Antimicrobial Resistance

Emerging Nanomaterials and Nano-based Drug Delivery Approaches to Combat Antimicrobial Resistance

Author: Muthupandian Saravanan

Publisher: Elsevier

Published: 2022-06-22

Total Pages: 790

ISBN-13: 0323998100

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Emerging Nanomaterials and Nano-based Drug Delivery Approaches to Combat Antimicrobial Resistance focuses on recent and emerging trends surrounding nanomaterials and nano-drug delivery approaches to combat antimicrobial resistance. The relationship between nanomaterials and antimicrobial activity needs to be deeply explored to meet the challenges of combating antimicrobial resistance. The content of this book is divided into three main topic areas, including (i) how to overcome the existing traditional approaches to combat antimicrobial resistance, (ii) applying multiple drug delivery mechanisms to target multi-drug resistant microbes, and (iii) how nanomaterials can be used as drug carriers. This is an important reference source for those looking to understand how nanotechnology plays an important role in combatting disease and infection. As antimicrobial resistance threatens the effective prevention and treatment of an ever-increasing range of infections caused by bacteria, parasites, viruses, and fungi, this is a timely resource. - Outlines how to overcome existing traditional approaches to combatting antimicrobial resistance - Explains how to apply multiple drug delivery mechanisms (MDR) to the target area in order to better combat antimicrobial resistance - Shows how nanomaterials are used as drug carriers in this context


Biopolymer-Based Nano Films

Biopolymer-Based Nano Films

Author: Mahendra Rai

Publisher: Elsevier

Published: 2021-02-02

Total Pages: 442

ISBN-13: 0128233826

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Biopolymer-Based Nano Films: Applications in Food Packaging and Wound Healing covers a variety of biofilms, including active biofilms, nisin-silver nano-films, silk fibroin-based composite films, lignocellulose/cellulose-based biofilms, carboxymethyl cellulose-coated polypropylene, hybrid film-loaded antimicrobials, chitosan hybrid systems, pullulan, and biopolymers films. The applications of these nano-biofilms in different fields, particularly in food packaging, wound healing, and as potential antimicrobials against new, emerging, and multidrug resistant microbes are also discussed. This is an important resource for researchers in the fields of pharmacology, nanotechnology, microbiology, biotechnology, and for clinicians. The possibility of associating nanotechnology with biotechnology helps with the creation of innovative new products and the development of processes at the molecular level. Within this context, nanobiotechnology advances and revolutionizes several scientific fields. In the development of new technologies and products, it is also necessary to develop "platforms" that allow the specific application and delivery of compounds/actives in a controlled, specific and non-toxic way. Covers a variety of biofilms Outlines the fundamental properties and major applications of nanostructured biofilms Associates nanotechnology with biotechnology and how they can help with the creation of innovative new products and the development of processes at the molecular level


Antiviral and Antimicrobial Coatings Based on Functionalized Nanomaterials

Antiviral and Antimicrobial Coatings Based on Functionalized Nanomaterials

Author: Shahid Ul Islam

Publisher: Elsevier

Published: 2023-06-15

Total Pages: 680

ISBN-13: 0323972772

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Antiviral and Antimicrobial Coatings Based on Functionalized Nanomaterials: Design, Applications, and Devices is the first book on functionalized nanoparticles-based coatings that encompasses the majority of aspects of antimicrobial and antiviral coatings. The use of functionalized nanoparticles has revolutionized all fields of science and engineering, and this book provides the reader with a fundamental, interdisciplinary look at this emerging field. It focuses on the most advanced coating systems being utilized by various industries including a discussion of the current challenges to be considered during manufacturing. This book provides both academics and those working in industry with a broad-based introduction to the area of modern antimicrobial coatings practices. - Describes functionalized nanoparticles-based antimicrobial and antiviral coatings utilized in modern industrial platforms - Evaluates functionalized nanoparticles-based antimicrobial and antiviral coatings as prime options for sustainable and transformational opportunities - Serves as a reference for scientists and engineers who are searching for modern design techniques for antimicrobial and antiviral coatings systems


Antimicrobial Activity of Nanoparticles

Antimicrobial Activity of Nanoparticles

Author: Gregory Guisbiers

Publisher: Elsevier

Published: 2022-08-30

Total Pages: 302

ISBN-13: 0128216387

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Antimicrobial Activity of Nanoparticles: Applications in Wound Healing and Infection Treatment presents the state of the art among nanotechnological approaches used in the treatment of infections. This field has gained a large amount of interest over the past few years, in response to the increasing resistance of pathogens to antibiotics. Leading researchers from around the world discuss the synthesis routes of nanobiomaterials, characterization, and their applications as antimicrobial agents. The book covers various aspects: from antiviral and antibacterial nanoparticles, to the functionalization of nanoparticles and their toxicity to human cells. This book offers an advanced reference text for biomedical engineers, materials scientists, clinicians, and biochemists, with an interest in nanomedicine and infection control. - Provides a targeted nanomaterial-based focus in antimicrobial medicine, bridging the gap between biological, clinical, and materials science disciplines - Describes the synthesis and characterization of nanoparticles for infection and wound healing, including chemical routes, biological routes, and physical routes - Covers each microbial subgroup and associated antimicrobial nanoparticles in individual, digestible sections


Nano Medicine and Nano Safety

Nano Medicine and Nano Safety

Author: Malay K. Das

Publisher: Springer Nature

Published: 2020-12-09

Total Pages: 634

ISBN-13: 9811562555

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This book reviews the application of Nanobiotechnology in the development of Nanomedicine, while also discussing the latest trends and challenges in the clinical translation of Nanomedicine. Nanomedicine refers to the application of Nanotechnology to medicine and holds tremendous potential for achieving improved efficiency, bioavailability, dose response, personalized medicine and enhanced safety as compared to conventional medicines. The book first introduces readers to the basic concepts of Nanomedicine, and to technological advances in and applications of Nanotechnology in treatment, diagnosis, monitoring, and drug delivery. In turn, it reviews the current status of multi-functionalization strategies for using Nanoparticles in the targeted delivery of therapeutic agents. The book’s third and final section focuses on the regulatory and safety challenges posed by Nanomedicine, including industry and regulatory agencies’ efforts to address them.


Tomorrow's Healthcare by Nano-sized Approaches

Tomorrow's Healthcare by Nano-sized Approaches

Author: Paula Veronica Messina

Publisher: CRC Press

Published: 2020-05-19

Total Pages: 272

ISBN-13: 0429682433

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Nanomedicine, a scientific branch of nanotechnology that operates on the same scale as biology, offers the possibility of influencing the healing process from inside of the body by manipulating the matter at cellular or molecular levels. Throughout this book, current healing approaches based on this revolutionary new technology are summarized from a scientific assessment. The aim of the authors is to give, through select examples, a deep insight to nanotechnology status and the great progress that its rigorous application will bring to human health. The authors' commitment is to broaden the vision of health professionals who will eventually be the future users of this knowledge.


Antimicrobial and Antiviral Materials

Antimicrobial and Antiviral Materials

Author: Peerawatt Nunthavarawong

Publisher: CRC Press

Published: 2022-05-19

Total Pages: 251

ISBN-13: 1000541215

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Emerging microbial and viral infections are a serious challenge to health, safety, and economics around the world. Antimicrobial and antiviral technologies are needed to disrupt the progression and replication of bacteria and viruses and to counter their rapidly evolving resistance. This book discusses recent developments in materials science and engineering in combating infectious diseases and explores advances in antimicrobial and antiviral materials, including polymers, metals, and ceramics and their applications in the fight against pathogens. Features • Covers progress in biomimetic antimicrobial and antiviral materials and antimicrobial/antiviral bulk materials and coatings • Describes modern methods for disinfection of biomedical materials against microbial and viral infection resistance, especially for depressing novel coronavirus (COVID-19) • Details methods to improve material properties to have a longer service life in combating infection • Emphasizes chemical, physical, mechanical, tribological, and antimicrobial/antiviral properties • Offers current and future applications of emerging antimicrobial/antiviral technologies This book will be of interest to materials researchers and industry professionals focusing on antimicrobial and antiviral applications.


Preclinical Evaluation of Antimicrobial Nanodrugs

Preclinical Evaluation of Antimicrobial Nanodrugs

Author: Juan Bueno

Publisher: Springer Nature

Published: 2020-05-08

Total Pages: 125

ISBN-13: 3030438554

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Translational medicine addresses the gap between research and the clinical application of new discoveries. To efficiently deliver new drugs to care centers, a preclinical evaluation, both in vitro and in vivo, is required to ensure that the most active and least toxic compounds are selected as well as to predict clinical outcome. Antimicrobial nanomedicines have been shown to have higher specificity in their therapeutic targets and the ability to serve as adjuvants, increasing the effectiveness of pre-existing immune compounds. The design and development of new standardized protocols for evaluating antimicrobial nanomedicines is needed for both the industry and clinical laboratory. These protocols must aim to evaluate laboratory activity and present models of pharmacokinetic-pharmacodynamic and toxicokinetic behavior that predict absorption and distribution. Likewise, these protocols must follow a theranostics approach, be able to detect promising formulations, diagnose the infectious disease, and determine the correct treatment to implement a personalized therapeutic behavior. Given the possibilities that nanotechnology offers, not updating to new screening platforms is inadequate as it prevents the correct application of discoveries, increasing the effect of the valley of death between innovations and their use. This book is structured to discuss the fundamentals taken into account for the design of robust, reproducible and automatable evaluation platforms. These vital platforms should enable the discovery of new medicines with which to face antimicrobial resistance (RAM), one of the great problems of our time.


Nanoarchitectonics for Smart Delivery and Drug Targeting

Nanoarchitectonics for Smart Delivery and Drug Targeting

Author: Alina Maria Holban

Publisher: William Andrew

Published: 2016-07-12

Total Pages: 972

ISBN-13: 0323477224

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Nanoarchitectonics for Smart Delivery and Drug Targeting is one of the first books on the market to exclusively focus on the topic of nanoarchitectonics, a rapidly developing area of nanotechnology which allows scientists to arrange nanoscale structural units, typically a group of atoms or molecules, in an intended configuration. This book assesses novel applications of nanomaterials in the areas of smart delivery and drug targeting using nanoarchitectonics and discusses the advantages and disadvantages of each application. - Provides a scholarly introduction to the uses of nanoarchitectonics in drug delivery and targeting - Explores novel opportunities and ideas for developing and improving nanoscale drug delivery systems through the use of nanoarchitectonics, allowing scientists to see how this exciting new technology is used in practice - Assesses the pros and cons of each application, allowing readers to assess when it is most appropriate to use nanoarchitectonics in drug delivery