Anti-aging Drugs
Anti-aging Drugs

Author: Alexander M Vaiserman

Publisher: Royal Society of Chemistry

Published: 2017-02-01

Total Pages: 592

ISBN-13: 178262435X

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Aging is a natural phenomenon that is peculiar to all living things. However, accumulating findings indicate that senescence could be postponed or prevented by certain approaches. Substantial evidence has emerged supporting the possibility of radical human health and lifespan extension, in particular through pharmacological modulation of aging. A number of natural dietary ingredients and synthetic drugs have been assumed to have geroprotective potential. In the development of anti-aging therapeutics, several cell, insect, and animal models may provide useful starting points prior to human studies. This book provides an overview of current research aimed to search for life-extending medications and describes pharmacological aspects of anti-aging medicine. Readers are introduced to the fascinating historical background of geroprotection in the first chapter. In-depth information on models for investigating geroprotective drugs precedes a section covering anti-aging properties of pharmaceutical compounds, such as calorie restriction mimetics, autophagy inducers, senolytics and mitochondrial antioxidants. Finally, strategies to translate discoveries from aging research into drugs and healthcare policy perspectives on anti-ageing medicine are provided to give a complete picture of the field. A timely and carefully edited collection of chapters by leading researchers in the field, this book will be a fascinating and useful resource for pharmacologists, gerontologists and any scientifically interested person wishing to know more about the current status of research into anti-aging remedies, challenges and opportunities.

Anti-ageing Medicine
Anti-ageing Medicine

Author: Astrid Stuckelberger

Publisher: vdf Hochschulverlag AG

Published: 2008

Total Pages: 330

ISBN-13: 3728131954

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The 21st century technological development is revolutionizing medicine and health care, bringing new hopes to human suffering by offering cures and treatments which were unthinkable a few decades ago. This is where anti-ageing medicine finds its niche. Anti-ageing medicine aims at slowing, arresting, and reversing phenomena associated with ageing by merging biotechnological innovation and engineered solutions. Ideally, by means of the newest medical technology, the "body machinery" should be kept fit and at peak performance all life long. Early detection of age-related dysfunction should thus be "fixed" at any age with interventions such as metabolic fine tuning, enhancement, regeneration, restoration or replacement of "body parts" (i.e. organs, skin, bone or muscle). It covers a vast array of domains: from cell therapy to pharmaceutical interventions, from bio-surgery to aesthetic surgery, from human enhancement to fortified food, from smart housing and robots to toxic-free environments. Anti-ageing medicine holds promises but also significant risks and safety issues which are addressesd in this book. It presents the latest scientific evidence on what works or does not work. It also provides public policy recommendations to ensure the protection of consumers and their rights while encouraging research and development. This book is intended for academics, health professionals, business persons, consumers and policy-makers interested in the latest evidence and ethical issues about anti-ageing medicine.

Systemic Delivery Technologies in Anti-Aging Medicine: Methods and Applications
Systemic Delivery Technologies in Anti-Aging Medicine: Methods and Applications

Author: Wing-Fu Lai

Publisher: Springer Nature

Published: 2020-10-19

Total Pages: 511

ISBN-13: 3030544907

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This book presents a multidisciplinary assessment of the state of science in the use of systemic delivery technologies to deliver anti-aging therapeutics now under development. There is a gap between basic aging research and the development of intervention technologies. This major obstacle must be overcome before biogerontological interventions can be put into clinical practice. As biogerontology comes to understand aging as a systemic degenerative process, it is clear that there is a pressing need for technologies that enable cells and tissues in a fully developed adult body to be manipulated systemically to combat aging. The authors review advances in the chemistry and engineering of systemic delivery methods and analyze the strengths and limitations of each. The book is organized into six sections. The first offers an overview of the need for systemic delivery technologies alongside the development of anti-aging therapies and describes approaches that will be required for studying the properties and efficiency of carriers for systemic delivery. Sections II, III and IV describe recent advances in a range of strategies that may enable systemic delivery to help combat aging conditions ranging from cell senescence to decline in immune function and hormonal secretion. Section V discusses practical strategies to engineer and optimize the performance of delivery technologies for applications in systemic delivery, along with their working principles. The final section discusses technical and biological barriers that must be overcome as systemic delivery technologies move from research laboratory to clinical applications aimed at tackling aging and age-associated diseases. Benefiting scholars, students and a broader audience of interested readers, the book includes helpful glossary sections in each chapter, as well as sidebars that highlight important notes, and questions for future research.

The Principles and Practice of Antiaging Medicine for the Clinical Physician
The Principles and Practice of Antiaging Medicine for the Clinical Physician

Author: Vincent C. Giampapa

Publisher: CRC Press

Published: 2022-09-01

Total Pages: 309

ISBN-13: 1000791432

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This book takes a whole new perspective concerning the approach to treating aging process. Most doctors feel they have no other options but to operate on the physical processes that occur as we grow older. Now, for the first time, there is another scientific approach that impacts on the causes of aging and not just on the effects.

Anti-Aging Medicine: How We Can Extend Lifespan and Live Longer and Healthier Lives
Anti-Aging Medicine: How We Can Extend Lifespan and Live Longer and Healthier Lives

Author: Theodore Goldsmith

Publisher: Azinet Press

Published: 2020-08-29

Total Pages: 138

ISBN-13: 9780978870966

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Aging is a treatable condition! For more than a century aging and a particular lifespan have been widely thought to be an inescapable and fundamental aspect of human existence. Indeed, Darwin's evolution theory tells us that the force of evolution is toward defeating aging, leading to the idea that aging is the result of unalterable laws of physics or chemistry. We can find different treatments for different age-related diseases like cancer and heart disease but aging is itself an untreatable fact of life. Today it is increasingly clear that aging is actually the result of complex biological programs that purposely limit lifespan in humans and most animals because this created an evolutionary advantage for populations of wild animals including our prehistoric ancestors. Programmed aging and supporting evolutionary concepts are a logical consequence of relatively recent discoveries in genetics as well as observations regarding the aging and lifespan characteristics of many different organisms. As a consequence, we can increase healthy human lifespan by interfering with the aging program. Interfering with a biological process is a familiar problem in medicine, and research toward developing treatments based on this idea are underway. Goldsmith describes the 160-year history of still-unresolved scientific arguments over the evolutionary nature of aging, the increasing empirical evidence of aging programs, and the exciting prospects for lifespan extension and healthy living. More practically, the book describes: Key observations about the nature of aging. Orally administered substances known to increase longevity in mice. Why exercise increases longevity. Anti-aging medicine issues with existing health care systems. Social, educational, ethical, and economic issues with extending lifespan. How lifespan extension concepts add to our ability to devise treatments for age-related diseases. Contents 1. Introduction 2. Nature of Aging and Lifespan 3. Evolution Theory and Aging 4. Evidence Supporting Programmed Aging 5. U.S. Health System Summary 6. Exercise and Activity - Effects on Aging 7. Non-Science Factors Favor Non-Programmed Aging 8. Programmed vs Non-Programmed Aging - Current Status 9. Anti-Aging Research 10. Anti-Aging Medicine 11. Conclusion 12. Free Resources and Further Reading 13. Author's Notes 14. Appendix 15. Glossary 16. References

Anti-Aging Therapeutics Volume XV
Anti-Aging Therapeutics Volume XV

Author: A4M American Academy of Anti-Aging Medicine

Publisher: A4M American Academy of Anti-Aging Medicine

Published: 2014-08-07

Total Pages: 230

ISBN-13: 1934715158

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Proceedings of the Twentieth World Congress on Anti-Aging Medicine & Regenerative Biomedical Technologies, Spring and Winter Sessions

Anti-Aging Therapeutics Volume XVI
Anti-Aging Therapeutics Volume XVI

Author: A4M American Academy of Anti-Aging Medicine

Publisher: A4M American Academy of Anti-Aging Medicine

Published: 2015-03-13

Total Pages: 191

ISBN-13: 1934715174

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Proceedings of the Twenty-First World Congress on Anti-Aging Medicine & Regenerative Biomedical Technologies, sponsored by the American Academy of Anti-Aging Medicine (A4M)

Stopping the Clock
Stopping the Clock

Author: Ronald Klatz

Publisher: Bantam

Published: 1997-07-01

Total Pages: 420

ISBN-13: 9780553577518

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Why many of us will live past 100--and enjoy our extra years. In Stopping the Clock, two pioneers of anti-aging medicine show how we can start now to regain energy and vitality, halt or reverse damage to our bodies, and avoid the diseases--heart attack, arthritis, cancer, diabetes--that do most to reduce current life expectancy. In sixteen fully-documented, information-packed chapters, Klatz and Goldman detail an up-to-the-minute longevity program, including: The key anti-aging hormones: Melatonin, DHEA, and human growth hormone, how to take them and precautions to use. The sex hormones: the role of estrogen and progesterone supplementation, including natural alternatives to prescription hormones--plus new research on testosterone supplementation for men and women. The role of the "miracle minerals"--chromium, selenium and magnesium--and the latest information on the key anti-oxidant vitamins and how to take them. A thyroid support program to avoid the many dangerous effects of thyroid deficiency. A sensible approach to anti-aging exercise--plus 25 ways to defeat the aging effects of stress. The life-long diet--including the top 25 healing foods. A longevity test to determine your current estimated lifespan. Personal longevity programs--including daily supplement regiments--from 28 leaders of anti-aging medicine. Glossary of 75 anti-aging substances available at health-food stores.