Analysis and Control of Boolean Networks
Analysis and Control of Boolean Networks

Author: Daizhan Cheng

Publisher: Springer Science & Business Media

Published: 2010-11-23

Total Pages: 474

ISBN-13: 0857290975

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Analysis and Control of Boolean Networks presents a systematic new approach to the investigation of Boolean control networks. The fundamental tool in this approach is a novel matrix product called the semi-tensor product (STP). Using the STP, a logical function can be expressed as a conventional discrete-time linear system. In the light of this linear expression, certain major issues concerning Boolean network topology – fixed points, cycles, transient times and basins of attractors – can be easily revealed by a set of formulae. This framework renders the state-space approach to dynamic control systems applicable to Boolean control networks. The bilinear-systemic representation of a Boolean control network makes it possible to investigate basic control problems including controllability, observability, stabilization, disturbance decoupling etc.

Probabilistic Boolean Networks
Probabilistic Boolean Networks

Author: Ilya Shmulevich

Publisher: SIAM

Published: 2010-01-21

Total Pages: 276

ISBN-13: 0898716926

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The first comprehensive treatment of probabilistic Boolean networks, unifying different strands of current research and addressing emerging issues.

Algebraic Biology
Algebraic Biology

Author: Katsuhisa Horimoto

Publisher: Springer Science & Business Media

Published: 2008-07-18

Total Pages: 256

ISBN-13: 3540851003

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This book constitutes the refereed proceedings of the Third International Conference on Algebraic Biology, AB 2008, held at the Castle of Hagenberg, Austria in July 2008 as part of the RISC Summer 2008, organized by the Research Institute for Symbolic Computation. The 14 revised full papers presented together with 3 tutorial lectures were carefully reviewed and selected from 27 submissions. The conference is the interdisciplinary forum for the presentation of research on all aspects of applications of symbolic computation (computer algebra, computational logic, and related methods) to various issues in biology and life sciences as well as other problems in biology being approached with symbolic methods.

Algorithms For Analysis, Inference, And Control Of Boolean Networks
Algorithms For Analysis, Inference, And Control Of Boolean Networks

Author: Tatsuya Akutsu

Publisher: World Scientific

Published: 2018-02-14

Total Pages: 227

ISBN-13: 9813233443

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The Boolean network (BN) is a mathematical model of genetic networks and other biological networks. Although extensive studies have been done on BNs from a viewpoint of complex systems, not so many studies have been undertaken from a computational viewpoint. This book presents rigorous algorithmic results on important computational problems on BNs, which include inference of a BN, detection of singleton and periodic attractors in a BN, and control of a BN. This book also presents algorithmic results on fundamental computational problems on probabilistic Boolean networks and a Boolean model of metabolic networks. Although most contents of the book are based on the work by the author and collaborators, other important computational results and techniques are also reviewed or explained.

Information Processing and Biological Systems
Information Processing and Biological Systems

Author: Samuli Niiranen

Publisher: Springer Science & Business Media

Published: 2011-03-10

Total Pages: 234

ISBN-13: 3642196217

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Living beings require constant information processing for survival. In cells, information is being processed and propagated at various levels, from the gene regulatory network to chemical pathways, to the interaction with the environment. How this is achieved and how information is coded is still poorly understood. For example, what a cell interprets as information in the temporal level of an mRNA and what is interpreted as noise remains an open question. Recently, information theoretical methods and other tools, developed in the context of engineering and natural sciences, have been applied to study diverse biological processes. This book covers the latest findings on how information is processed in various biological processes, ranging from information processing and propagation in gene regulatory networks to information processing in natural language. An overview is presented of the state-of-the-art in information processing in biological systems and the opinion of current leaders in this research field on future research directions.

Control Theory and Systems Biology
Control Theory and Systems Biology

Author: Pablo A. Iglesias

Publisher: MIT Press

Published: 2010

Total Pages: 359

ISBN-13: 0262013347

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A survey of how engineering techniques from control and systems theory can be used to help biologists understand the behavior of cellular systems.

Handbook on Biological Networks
Handbook on Biological Networks

Author: Stefano Boccaletti

Publisher: World Scientific

Published: 2010

Total Pages: 465

ISBN-13: 9812838791

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Networked systems are all around us. The accumulated evidence of systems as complex as a cell cannot be fully understood by studying only their isolated constituents, giving rise to a new area of interest in research ? the study of complex networks. In a broad sense, biological networks have been one of the most studied networks, and the field has benefited from many important contributions. By understanding and modeling the structure of a biological network, a better perception of its dynamical and functional behavior is to be expected. This unique book compiles the most relevant results and novel insights provided by network theory in the biological sciences, ranging from the structure and dynamics of the brain to cellular and protein networks and to population-level biology.

Analysis and Control of Finite-Valued Systems
Analysis and Control of Finite-Valued Systems

Author: Haitao Li

Publisher: CRC Press

Published: 2018-05-11

Total Pages: 276

ISBN-13: 1351368303

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A comprehensive work in finite-value systems that covers the latest achievements using the semi-tensor product method, on various kinds of finite-value systems. These results occupy the highest position in the analysis and control of this field. It not only covers all aspects of research in finite-value systems, but also presents the mathematical derivation for each conclusion in depth. The book contains examples to provide a better understanding of the practical applications of finite-value systems. It will serve as a textbook for graduate students of Cybernetics, Mathematical, and Biology, and a reference for readers interested in the theory of finite-value systems.

Control of Complex Systems
Control of Complex Systems

Author: Aleksandar Zecevic

Publisher: Springer Science & Business Media

Published: 2010-01-08

Total Pages: 233

ISBN-13: 1441912169

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"Control of Complex Systems: Structural Constraints and Uncertainty" focuses on control design under information structure constraints, with a particular emphasis on large-scale systems. The complexity of such systems poses serious computational challenges and severely restricts the types of feedback laws that can be used in practice. This book systematically addresses the main issues, and provides a number of applications that illustrate potential design methods, most which use Linear Matrix Inequalities (LMIs), which have become a popular design tool over the past two decades. Authors Aleksandar I. Zecevic and Dragoslav D. Siljak use their years of experience in the control field to also: Address the issues of large-scale systems as they relate to robust control and linear matrix inequalities Discuss a new approach to applying standard LMI techniques to large-scale systems, combining graphic-theoretic decomposition techniques with appropriate low-rank numerical approximations and dramatically reducing the computational effort Providing numerous examples and a wide variety of applications, ranging from electric power systems and nonlinear circuits to mechanical problems and dynamic Boolean networks "Control of Complex Systems: Structural Constraints and Uncertainty" will appeal to practicing engineers, researchers and students working in control design and other related areas.

Genomic Control Process
Genomic Control Process

Author: Isabelle S. Peter

Publisher: Academic Press

Published: 2015-01-21

Total Pages: 461

ISBN-13: 0124047467

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Genomic Control Process explores the biological phenomena around genomic regulatory systems that control and shape animal development processes, and which determine the nature of evolutionary processes that affect body plan. Unifying and simplifying the descriptions of development and evolution by focusing on the causality in these processes, it provides a comprehensive method of considering genomic control across diverse biological processes. This book is essential for graduate researchers in genomics, systems biology and molecular biology seeking to understand deep biological processes which regulate the structure of animals during development. - Covers a vast area of current biological research to produce a genome oriented regulatory bioscience of animal life - Places gene regulation, embryonic and postembryonic development, and evolution of the body plan in a unified conceptual framework - Provides the conceptual keys to interpret a broad developmental and evolutionary landscape with precise experimental illustrations drawn from contemporary literature - Includes a range of material, from developmental phenomenology to quantitative and logic models, from phylogenetics to the molecular biology of gene regulation, from animal models of all kinds to evidence of every relevant type - Demonstrates the causal power of system-level understanding of genomic control process - Conceptually organizes a constellation of complex and diverse biological phenomena - Investigates fundamental developmental control system logic in diverse circumstances and expresses these in conceptual models - Explores mechanistic evolutionary processes, illuminating the evolutionary consequences of developmental control systems as they are encoded in the genome