Cure Models

Cure Models

Author: Yingwei Peng

Publisher: CRC Press

Published: 2021-03-22

Total Pages: 268

ISBN-13: 0429629680

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Cure Models: Methods, Applications and Implementation is the first book in the last 25 years that provides a comprehensive and systematic introduction to the basics of modern cure models, including estimation, inference, and software. This book is useful for statistical researchers and graduate students, and practitioners in other disciplines to have a thorough review of modern cure model methodology and to seek appropriate cure models in applications. The prerequisites of this book include some basic knowledge of statistical modeling, survival models, and R and SAS for data analysis. The book features real-world examples from clinical trials and population-based studies and a detailed introduction to R packages, SAS macros, and WinBUGS programs to fit some cure models. The main topics covered include the foundation of statistical estimation and inference of cure models for independent and right-censored survival data, cure modeling for multivariate, recurrent-event, and competing-risks survival data, and joint modeling with longitudinal data, statistical testing for the existence and difference of cure rates and sufficient follow-up, new developments in Bayesian cure models, applications of cure models in public health research and clinical trials.


Spectrum Test Prep, Grade 1

Spectrum Test Prep, Grade 1

Author: Spectrum

Publisher: Carson-Dellosa Publishing

Published: 2015-01-05

Total Pages: 132

ISBN-13: 1483818578

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Spectrum Test Prep Grade 1 includes strategy-based activities for language arts and math, test tips to help answer questions, and critical thinking and reasoning. The Spectrum Test Prep series for grades 1 to 8 was developed by experts in education and was created to help students improve and strengthen their test-taking skills. The activities in each book not only feature essential practice in reading, math, and language arts test areas, but also prepare students to take standardized tests. Students learn how to follow directions, understand different test formats, use effective strategies to avoid common mistakes, and budget their time wisely. Step-by-step solutions in the answer key are included. These comprehensive workbooks are an excellent resource for developing skills for assessment success. Spectrum, the best-selling workbook series, is proud to provide quality educational materials that support your students’ learning achievement and success.


Freshwater Bivalve Ecotoxicology

Freshwater Bivalve Ecotoxicology

Author: Jerry L. Farris

Publisher: CRC Press

Published: 2006-11-16

Total Pages: 400

ISBN-13: 1420042858

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Responding to the growing need for an aggressive yet conservative approach to evaluating mussel populations, Freshwater Bivalve Ecotoxicology provides a collective review of the techniques and approaches for assessing contaminant impact on freshwater ecosystems. The editors incorporate coverage of research topics and management issues from a cross-section of scientists in the field. They explore current advances in general monitoring of population responses to stressors, fundamental concepts of ecotoxicology specific to burrowing bivalves, and useful insights that offer direction and priority for resolving specific problems challenging protection and conservation efforts. This book lays the groundwork with discussions of topics such as impact assessment, toxicokinetics, biomarkers, and pollution tolerance. The authors then explore fundamental concepts surrounding responses measured in freshwater bivalves as a consequence of chemical exposures or accumulated contaminants in target organs or tissues. They highlight the difficulties encountered with the laboratory culture of these organisms for toxicity testing or other controlled experiments, and examine the use of surrogate test organisms to relate sensitivities of response and reduce pressure on already impacted fauna. The book also reviews innovative field research using in situ bivalve toxicity testing, discusses effects-oriented tissue contaminant assessment, and concludes with threefour specific laboratory or combined field/laboratory ecotoxicology studies. A summary of methods from more than 75 laboratory toxicity studies conducted with freshwater mussels, the book provides an overview of a standardized method for conducting water-only acute and chronic laboratory toxicity tests with glochidia juvenile freshwater mussels. It focuses on studies that report measured contaminant treatments, had robust experimental designs, including replication of control and contaminant treatments, and were published in the peer-reviewed literature. The resulting array of viewpoints provides a framework that can be used to establish priorities in the rehabilitation and management of freshwater ecosystems.


King Croesus' Gold

King Croesus' Gold

Author: Andrew Ramage

Publisher: British Museum Press

Published: 2000

Total Pages: 288

ISBN-13:

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The continuing Archaeological Exploration of Sardis has excavated the remains of a gold refinery at the site, dating from the sixth century BC at the very inception of bimetallic coinage.".