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Author: Intratec
Publisher: Intratec
Published: 2019-09-17
Total Pages: 102
ISBN-13:
DOWNLOAD EBOOKThis report presents a cost analysis of Alpha-Cyclodextrin production from corn. The process examined is a typical solvent process. This report was developed based essentially on the following reference(s): Keywords: Cyclodextrin Glycosyl Transferase, Beta-Cyclodextrin, Gama-Cyclodextrin, CD
Author: Intratec
Publisher: Intratec Solutions
Published: 2016-05-01
Total Pages: 52
ISBN-13: 1945324554
DOWNLOAD EBOOKThis report presents a cost analysis of second generation Ethanol production from corn stover via a biochemical conversion process. The process examined is similar to the process reported by the National Renewable Energy Laboratory (NREL). This process involves the following steps in the production of hydrous Ethanol: corn stover pretreatment with dilute acid and ammonia conditioning; enzymatic hydrolysis; and fermentation. Electricity is also generated as by-product. This report examines one-time costs associated with the construction of a United States-based plant and the continuing costs associated with the daily operation of such a plant. More specifically, it discusses: * Capital Investment, broken down by: - Total fixed capital required, divided in production unit (ISBL); infrastructure (OSBL) and contingency - Alternative perspective on the total fixed capital, divided in direct costs, indirect costs and contingency - Working capital and costs incurred during industrial plant commissioning and start-up * Production cost, broken down by: - Manufacturing variable costs (raw materials, utilities) - Manufacturing fixed costs (maintenance costs, operating charges, plant overhead, local taxes and insurance) - Depreciation and corporate overhead costs * Raw materials consumption, products generation and labor requirements * Process block flow diagram and description of industrial site installations (production unit and infrastructure) This report was developed based essentially on the following reference(s): Humbird, D., et al., "Process Design and Economics for Biochemical Conversion of Lignocellulosic Biomass to Ethanol, " Report NREL/TP-5100-47764, National Renewable Energy Laboratory (NREL), 2011 Keywords: Ethyl Alcohol, Bioethanol, Lignocellulosic Biomass, 2nd Generation, Cellulosic Sugar, Hemicelluloses, Cellulose
Author: Muhammad Asif Hanif
Publisher: Elsevier
Published: 2019-09-14
Total Pages: 770
ISBN-13: 0081026609
DOWNLOAD EBOOKMedicinal Plants of South Asia: Novel Sources for Drug Discovery provides a comprehensive review of medicinal plants of this region, highlighting chemical components of high potential and applying the latest technology to reveal the underlying chemistry and active components of traditionally used medicinal plants. Drawing on the vast experience of its expert editors and authors, the book provides a contemporary guide source on these novel chemical structures, thus making it a useful resource for medicinal chemists, phytochemists, pharmaceutical scientists and everyone involved in the use, sales, discovery and development of drugs from natural sources. - Provides comprehensive reviews of 50 medicinal plants and their key properties - Examines the background and botany of each source before going on to discuss underlying phytochemistry and chemical compositions - Links phytochemical properties with pharmacological activities - Supports data with extensive laboratory studies of traditional medicines
Author: Monika Schäfer-Korting
Publisher: Springer Science & Business Media
Published: 2010-03-10
Total Pages: 506
ISBN-13: 3642004776
DOWNLOAD EBOOKIn the view of most experts pharmacology is on drugs, targets, and actions. In the context the drug as a rule is seen as an active pharmaceutical ingredient and not as a complex mixture of chemical entities of a well defined structure. Today, we are becoming more and more aware of the fact that delivery of the active compound to the target site is a key. The present volume gives a topical overview on various modern approaches to drug targeting covering today’s options for specific carrier systems allowing successful drug treatment at various sites of the body difficult to address and allowing to increase the benefit-risk-ratio to the optimum possible.
Author: Giridhara R. Jayandharan
Publisher: Springer
Published: 2018-09-12
Total Pages: 316
ISBN-13: 9811304815
DOWNLOAD EBOOKRecent advances in stem cell biology, nanotechnology and gene therapy have opened new avenues for therapeutics. The availability of molecular therapeutics that rely on the delivery of DNA, RNA or proteins, harnessing enhanced delivery with nanoparticles, and the regenerative potential of stem cells (adult, embryonic or induced pluripotent stem cells) has had a tremendous impact on translational medicine. The chapters in this book cover a range of strategies for molecular and cellular therapies for human disease, their advantages, and central challenges to their widespread application. Potential solutions to these issues are also discussed in detail. Further, the book addresses numerous advances in the field of molecular therapeutics that will be of interest to the general scientific community. Lastly, the book provides specific examples of disease conditions for which these strategies have been transferred to the clinic. As such, it will be extremely useful for all students, researchers and clinicians working in the field of translational medicine and molecular therapeutics.
Author: Md Amin Hashim
Publisher: Springer
Published: 2015-06-15
Total Pages: 403
ISBN-13: 9812875050
DOWNLOAD EBOOKThis book includes selected papers from the ICGSCE 2014 with focus on the current trends of global resources used to meet the growing demands to improve life style coupled with environmental and social problems related to the resource consumption with emphasize to move towards sustainable development. It provides a platform for scientists and academicians from local and international universities and industries to promote, share and discuss various new issues and developments in different areas of Chemical Engineering with respect to global sustainability. Under the sustainability umbrella the topics covered are; alternative energy sources, alternative feedstock for energy and chemicals, alternative raw materials for household commodity, green process with minimal environmental impact, process intensification, waste minimization, recycling of wastes and providing quality water, food and medicines. Other topics covered include: 1. Oil and gas, Biofuel, Fuel cell, Renewable energy 2. Green technology, Sustainability, Environmental, Carbon sequestration, Carbon footprint, Natural resources 3. Chemical processes, Separation technology, Biotechnology, Nanotechnology, Food technology, Particle technology, Corrosion, Pharmaceutical, Phytochemical, Oleochemical 4. Process modeling, Process Simulation, Process control 5. Advanced material, Polymer, Catalyst, Enzyme 6. Policy, Regulations, Strategy and implementation, Safety, Management of science, Engineering education 7. Process Safety and Loss Prevention, Environmental and chemical risk assessment, Transportation risk analysis, Inherent safety.
Author: Daniel Bar-Shalom
Publisher: Springer Science & Business Media
Published: 2014-01-30
Total Pages: 429
ISBN-13: 1489980113
DOWNLOAD EBOOKUntil the 1990s, it was generally accepted that medicines were first developed for adults and their use in children was investigated later, if at all. One of the main tasks of hospital pharmacies was the manufacturing of child-appropriate formulations in a more or less makeshift way. The first change came in 1997 with U.S. legislation that rewarded manufacturers to do voluntary pediatric research. Ten years later, the European Union passed legislation that required manufacturers to discuss all pediatric aspects, including formulations, with the regulatory authorities as a condition of starting the registration procedure. In consequence, manufacturers must now cover all age groups, including the youngest ones. So far, pediatric formulations were more a focus for academic researchers. Through the changed regulatory environment, there is now a sudden high commercial demand for age-appropriate formulations. This book begins by highlighting the anatomical, physiological and developmental differences between adults and children of different ages. It goes on to review the existing technologies and attempts to draw a roadmap to better, innovative formulations, in particular for oral administration. The regulatory, clinical, ethical and pharmaceutical framework is also addressed.
Author: Hui Sun
Publisher: Methods in Molecular Biology
Published: 2010-06-08
Total Pages: 384
ISBN-13:
DOWNLOAD EBOOKExciting new biological functions are still being discovered for vitamin A derivatives, including the myriad physiological activities of retinoids. Here, experts in the field present the latest range of techniques for both in-vitro and in-vivo studies.
Author: Abraham J. Domb
Publisher: Springer Science & Business Media
Published: 2014-02-17
Total Pages: 700
ISBN-13: 1461494346
DOWNLOAD EBOOKThe concept of focal controlled drug delivery has been applied for treating illnesses that are localized to a certain tissue or organ. These delivery systems are applied directly to the diseased site and deliver a desired dose for an extended time period while minimizing systemic distribution of toxic drug. Controlled drug delivery systems have been focused on oral extended release formulations and on systemic delivery of small drugs and peptides. Despite the upsurge of interest in focal targeted drug delivery, there is currently no single reference text on the subject. By comparison, there are numerous authored and edited books on oral, systemic and transdermal drug delivery or books on biodegradable polymers as drug carriers. Thus, the aim of Focal Drug Delivery is to bring together leading experts and researchers in the field to provide an authoritative account of the essential pharmaceutical, technological, physiological and biological sciences underpinning the topic. In addition, the book will review advances in treatment options for diseases localized at a certain tissue or organ.
Author: Alok K. Kulshreshtha
Publisher: Springer Science & Business Media
Published: 2009-11-05
Total Pages: 337
ISBN-13: 1441910875
DOWNLOAD EBOOKThe suspension dosage form has long been used for poorly soluble active ingre- ents for various therapeutic indications. Development of stable suspensions over the shelf life of the drug product continues to be a challenge on many fronts. A good understanding of the fundamentals of disperse systems is essential in the development of a suitable pharmaceutical suspension. The development of a s- pension dosage form follows a very complicated path. The selection of the proper excipients (surfactants, viscosity imparting agents etc.) is important. The particle size distribution in the finished drug product dosage form is a critical parameter that significantly impacts the bioavailability and pharmacokinetics of the product. Appropriate analytical methodologies and instruments (chromatographs, visco- ters, particle size analyzers, etc.) must be utilized to properly characterize the s- pension formulation. The development process continues with a successful scale-up of the manufacturing process. Regulatory agencies around the world require cli- cal trials to establish the safety and efficacy of the drug product. All of this devel- ment work should culminate into a regulatory filing in accordance with the regulatory guidelines. Pharmaceutical Suspensions, From Formulation Development to Manufacturing, in its organization, follows the development approach used widely in the pharmaceutical industry. The primary focus of this book is on the classical disperse system – poorly soluble active pharmaceutical ingredients s- pended in a suitable vehicle.
