Advances in Bioinformatics
Advances in Bioinformatics

Author: Vijai Singh

Publisher: Springer Nature

Published: 2021-07-31

Total Pages: 446

ISBN-13: 9813361913

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This book presents the latest developments in bioinformatics, highlighting the importance of bioinformatics in genomics, transcriptomics, metabolism and cheminformatics analysis, as well as in drug discovery and development. It covers tools, data mining and analysis, protein analysis, computational vaccine, and drug design. Covering cheminformatics, computational evolutionary biology and the role of next-generation sequencing and neural network analysis, it also discusses the use of bioinformatics tools in the development of precision medicine. This book offers a valuable source of information for not only beginners in bioinformatics, but also for students, researchers, scientists, clinicians, practitioners, policymakers, and stakeholders who are interested in harnessing the potential of bioinformatics in many areas.

Advances In Bioinformatics And Its Applications - Proceedings Of The International Conference
Advances In Bioinformatics And Its Applications - Proceedings Of The International Conference

Author: Matthew He

Publisher: World Scientific

Published: 2005-05-03

Total Pages: 633

ISBN-13: 9814481017

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This unique volume presents major developments and trends in bioinformatics and its applications. Comprising high-quality scientific research papers and state-of-the-art survey articles, the book has been divided into five main sections: Microarray Analysis and Regulatory Networks; Machine Learning and Statistical Analysis; Biomolecular Sequence and Structure Analysis; Symmetry in Sequences; and Signal Processing, Image Processing and Visualization. The results of these investigations help the practicing biologist in many ways: in identifying unknown connections, in narrowing down possibilities for a search, in suggesting new hypotheses, designing new experiments, validating existing models or proposing new ones. It is an essential source of reference for researchers and graduate students in bioinformatics, computer science, mathematics, statistics, and biological sciences based on select papers from the “The International Conference on Bioinformatics and Its Application” (ICBA), held December 16-19, 2004 in Fort Lauderdale, Florida, USA.

Advances in Bioinformatics, Biostatistics and Omic Sciences
Advances in Bioinformatics, Biostatistics and Omic Sciences

Author: Luigi Donato

Publisher: Bentham Science Publishers

Published: 2020-11-30

Total Pages: 148

ISBN-13: 9811481784

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Bioinformatics, and by extension omic sciences – the collective disciplines that are dependent on the use of extensive datasets of biological information – present a challenge of data management for researchers all over the world. Big data collected as part of research projects and experiments can be complex, with several kinds of variables involved. Coupled with continuously changing bioinformatics and information technology tools, there is a need to bring a multidisciplinary approach into these fields. Advances in Bioinformatics, Biostatistics and Omic Sciences attempts to realize an integrated approach between all omic sciences, exploring innovative bioinformatics and biostatistical methodologies which enable researchers to unveil hidden sides of biological phenomena. This volume presents reviews on the following topics which give a glimpse of recent advances in the field: - New Integrated Mitochondrial DNA Bioinformatics Pipeline to Improve Quality Assessment of Putative Pathogenic Variants from NGS Experiments - Variant Calling on RNA Sequencing Data: State of Art and Future Perspectives - An innovative Gene Prioritization Pipeline for WES analyses - New Integrated Differential Expression Approach for RNA-Seq Data Analysis - Innovations in Data Visualization for Straightforward Interpretation of Nucleic Acid Omics Outcomes This volume serves as a guide for graduate students in bioinformatics as well as researchers planning new projects as a part of their professional and academic activities.

Systemic Approaches in Bioinformatics and Computational Systems Biology
Systemic Approaches in Bioinformatics and Computational Systems Biology

Author: Paola Lecca

Publisher:

Published: 2012

Total Pages: 0

ISBN-13: 9781613504352

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"This book presents new techniques that have resulted from the application of computer science methods to the organization and interpretation of biological data, covering three subject areas: bioinformatics, computational biology, and computational systems biology"--

Algorithmic Aspects of Bioinformatics
Algorithmic Aspects of Bioinformatics

Author: Hans-Joachim Böckenhauer

Publisher: Springer Science & Business Media

Published: 2007-06-06

Total Pages: 395

ISBN-13: 354071913X

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This book introduces some key problems in bioinformatics, discusses the models used to formally describe these problems, and analyzes the algorithmic approaches used to solve them. After introducing the basics of molecular biology and algorithmics, Part I explains string algorithms and alignments; Part II details the field of physical mapping and DNA sequencing; and Part III examines the application of algorithmics to the analysis of biological data. Exciting application examples include predicting the spatial structure of proteins, and computing haplotypes from genotype data. Figures, chapter summaries, detailed derivations, and examples, are provided.

Applications Of Fuzzy Logic In Bioinformatics
Applications Of Fuzzy Logic In Bioinformatics

Author: Dong Xu

Publisher: World Scientific

Published: 2008-08-11

Total Pages: 246

ISBN-13: 1908978716

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Many biological systems and objects are intrinsically fuzzy as their properties and behaviors contain randomness or uncertainty. In addition, it has been shown that exact or optimal methods have significant limitation in many bioinformatics problems. Fuzzy set theory and fuzzy logic are ideal to describe some biological systems/objects and provide good tools for some bioinformatics problems. This book comprehensively addresses several important bioinformatics topics using fuzzy concepts and approaches, including measurement of ontological similarity, protein structure prediction/analysis, and microarray data analysis. It also reviews other bioinformatics applications using fuzzy techniques./a

Computational Methods for Understanding Bacterial and Archaeal Genomes
Computational Methods for Understanding Bacterial and Archaeal Genomes

Author: Ying Xu

Publisher: World Scientific

Published: 2008

Total Pages: 494

ISBN-13: 1860949827

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Over 500 prokaryotic genomes have been sequenced to date, and thousands more have been planned for the next few years. While these genomic sequence data provide unprecedented opportunities for biologists to study the world of prokaryotes, they also raise extremely challenging issues such as how to decode the rich information encoded in these genomes. This comprehensive volume includes a collection of cohesively written chapters on prokaryotic genomes, their organization and evolution, the information they encode, and the computational approaches needed to derive such information. A comparative view of bacterial and archaeal genomes, and how information is encoded differently in them, is also presented. Combining theoretical discussions and computational techniques, the book serves as a valuable introductory textbook for graduate-level microbial genomics and informatics courses.

Information Processing And Living Systems
Information Processing And Living Systems

Author: Vladimir B Bajic

Publisher: World Scientific

Published: 2005-06-01

Total Pages: 799

ISBN-13: 1783260270

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Information processing and information flow occur in the course of an organism's development and throughout its lifespan. Organisms do not exist in isolation, but interact with each other constantly within a complex ecosystem. The relationships between organisms, such as those between prey or predator, host and parasite, and between mating partners, are complex and multidimensional. In all cases, there is constant communication and information flow at many levels.This book focuses on information processing by life forms and the use of information technology in understanding them. Readers are first given a comprehensive overview of biocomputing before navigating the complex terrain of natural processing of biological information using physiological and analogous computing models. The remainder of the book deals with “artificial” processing of biological information as a human endeavor in order to derive new knowledge and gain insight into life forms and their functioning. Specific innovative applications and tools for biological discovery are provided as the link and complement to biocomputing.Since “artificial” processing of biological information is complementary to natural processing, a better understanding of the former helps us improve the latter. Consequently, readers are exposed to both domains and, when dealing with biological problems of their interest, will be better equipped to grasp relevant ideas.

Biotechnology and Bioinformatics
Biotechnology and Bioinformatics

Author: Devarajan Thangadurai

Publisher: CRC Press

Published: 2014-07-01

Total Pages: 526

ISBN-13: 1771880015

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Reflecting the interdisciplinary nature of biotechnology, this book covers the role of targeted delivery of polymeric nanodrugs to cancer cells, microbial detoxifying enzymes in bioremediation and bacterial plasmids in antimicrobial resistance. It addresses modern trends such as pharmacogenomics, evaluation of gene expression, recombinant proteins from methylotrophic yeast, identification of novel fermentation inhibitors of bioethanol production, and polyhydroxyalkanoate based biomaterials. The book highlights the practical utility of biotechnology and bioinformatics for bioenergy, production of high value biochemicals, modeling molecular interactions, drug discovery, and personalized medicine.