Advancement of Phenolic Acids in Drug Discovery
Advancement of Phenolic Acids in Drug Discovery

Author: Naresh Kumar

Publisher: Elsevier

Published: 2024-06-19

Total Pages: 540

ISBN-13: 0443185395

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Advancement of Phenolic Acids in Drug Discovery: Fundamental and Applications offers comprehensive coverage of the ADMET profiles of phenolic acids, their extraction method and prospects for drug design and development. Chapters overview phenolic acids and their characterization, discuss the role of phenolic acids in plant systems, present sources and detailed extraction methods of phenolic acids, and cover phenolic acid mechanisms of action as it relates to several key diseases and health conditions, including their role as antioxidant agents, anti-inflammatory and analgesic drugs, anti-microbial drugs, anti-viral drugs, anti-cancer drugs, diabetes and metabolic dysfunctions, neurological disorders, cardiovascular diseases. The book's final chapters cover nanoscience aspects of phenolic acids, biomedical applications, and concludes with challenges and opportunities presented by phenolic acids. This is the ideal reference for researchers in the fields of drug development, both in academia and corporate settings. Researchers of related areas like food science and medicinal chemistry will also benefit from this in-depth profiling of therapeutical properties of phenolic acids. - Highlights fundamental concepts with advanced exploration of phenolic acids - Provides in-depth coverage on the design and development of novel drugs from natural phenolic acids - Reviews the changing role of phenolic acids

Advances in Drug discovery and Quality Evaluation
Advances in Drug discovery and Quality Evaluation

Author: Xuetao Xu

Publisher: Frontiers Media SA

Published: 2023-11-24

Total Pages: 120

ISBN-13: 283253967X

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Drug discovery and quality evaluation are very important for human health. Drugs from chemical synthesis and natural products are a very important branch in drug discovery. The highly efficient synthetic methodology development and pharmacological evaluation of related active agents, as essential steps to developing corresponding innovative drugs, are always research frontiers for organic chemists and medicinal chemists. Meanwhile, the drug quality evaluation is an important guarantee for the clinical application of drugs and the efficacy of drugs. Therefore, we wanted to organize this article collection for the presentation of the high-quality work from internationally recognized researchers to promote academic communication among scientific researchers focusing on medicinal and pharmaceutical chemistry. In recent years, the research community has witnessed significant advances in the development of the discovery of novel natural products, design and synthesis of bioactive molecules, synthetic methodology, and drug quality evaluation. Therefore, we hope to be able to summarize and display the latest developments in the design and synthesis of bioactive molecules, synthetic methodologies, the discovery of novel natural products, as well as drugs quality evaluation through the collection of this album, and provide new methods and template molecules for the subsequent development of innovative drug molecules.

Pharmacological Advances in Natural Product Drug Discovery
Pharmacological Advances in Natural Product Drug Discovery

Author:

Publisher: Academic Press

Published: 2020-02-21

Total Pages: 364

ISBN-13: 012820186X

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Pharmacological Advances in Natural Product Drug Discovery, Volume 87 in the Advances in Pharmacology series, presents the latest pharmacological research progresses of 8 medicinal compounds from natural products, including salvianolic acid, tanshinone, paeonol, chlorogenic acid, astragaloside, icariin, ganoderan, and febrifugine. Specific chapters to this new release include Potential Role of Paeonol on Atherosclerosis Related Cells, A Review on Salvianolic Acid, Pharmacological Advances of Tanshinones, the Natural Product of Salvia Miltiorrhiza, Pharmacological Action and Potential Targets Analysis of Major Pharmacological Effects of Chlorogenic Acid, Modern TCM: Identifying and Defining the "Medicinal Mix", Pharmacological Advances in Astragaloside IV Derived from Astragalus Membranaceus, and much more. - Includes the authority and expertise of leading contributors in natural product pharmacology - Provides the latest pharmacological research progresses of eight medicinal compounds from natural products - Presents a thorough discussion on the compatibility of traditional medicines

Phenolics in Food and Nutraceuticals
Phenolics in Food and Nutraceuticals

Author: Fereidoon Shahidi

Publisher: CRC Press

Published: 2003-07-29

Total Pages: 576

ISBN-13: 0203508734

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Phenolics in Food and Nutraceuticals is the first single-source compendium of essential information concerning food phenolics. This unique book reports the classification and nomenclature of phenolics, their occurrence in food and nutraceuticals, chemistry and applications, and nutritional and health effects. In addition, it describes antioxidant a

Drugs—Advances in Research and Application: 2012 Edition
Drugs—Advances in Research and Application: 2012 Edition

Author:

Publisher: ScholarlyEditions

Published: 2012-12-26

Total Pages: 1195

ISBN-13: 1464990891

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Drugs—Advances in Research and Application / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Drugs. The editors have built Drugs—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Drugs in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Drugs—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Water Extraction of Bioactive Compounds
Water Extraction of Bioactive Compounds

Author: Herminia Dominguez

Publisher: Elsevier

Published: 2017-09-20

Total Pages: 486

ISBN-13: 0128096152

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Water Extraction of Bioactive Compounds: From Plants to Drug Development draws together the expert knowledge of researchers from around the world to outline the essential knowledge and techniques required to successfully extract bioactive compounds for further study. The book is a practical tool for medicinal chemists, biochemists, pharmaceutical scientists and academics working in the discovery and development of drugs from natural sources. The discovery and extraction of bioactive plant compounds from natural sources is of growing interest to drug developers, adding greater fuel to a simultaneous search for efficient, green technologies to support this. Particularly promising are aqueous based methods, as water is a cheap, safe and abundant solvent. Water Extraction of Bioactive Compounds: From Plants to Drug Development is a detailed guide to the fundamental concepts and considerations needed to successfully undertake such processes, supported by application examples and highlighting the most influential variables. Beginning with an introduction to plants as sources of drugs, the book highlights the need for a move towards both more rational and greener techniques in the field, and presents multiple innovative water-based strategies for the discovery and extraction of bioactive constituents of botanicals. A broad range of available techniques are reviewed, including conventional and pressurized hot water extraction techniques, intensified processes such as microwave-assisted, ultrasound-assisted processes, and enzyme assisted extraction, and processes using combined techniques. - Covers the theoretical background and range of techniques available to researchers, helping them to select the most appropriate extraction method for their needs - Presents up-to-date and cutting edge applications by international experts - Highlights current use and future potential for industrial scale applications - Offers a thorough introduction to plants as sources of drugs, highlighting strategies for the discovery of novel bioactive constituents of botanicals

Phenolic Compounds in Foods and Natural Health Products
Phenolic Compounds in Foods and Natural Health Products

Author: Fereidoon Shahidi

Publisher:

Published: 2005

Total Pages: 328

ISBN-13:

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The book reviewed and gave new research discovery of the chemistry, analysis and health effects such as antioxidative, cancer preventive and anti-inflammatory properties of phenolic compounds in foods and natural health products.

Lyases: Advances in Research and Application: 2011 Edition
Lyases: Advances in Research and Application: 2011 Edition

Author:

Publisher: ScholarlyEditions

Published: 2012-01-09

Total Pages: 49

ISBN-13: 1464939594

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Lyases: Advances in Research and Application: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Lyases in a concise format. The editors have built Lyases: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Lyases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Lyases: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Biotechnology and Drug Development for Targeting Human Diseases
Biotechnology and Drug Development for Targeting Human Diseases

Author: Israel Valencia Quiroz

Publisher: Bentham Science Publishers

Published: 2024-03-14

Total Pages: 235

ISBN-13: 9815223178

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Biotechnology and Drug Development for Targeting Human Diseases is an insightful compendium on drug development technologies for professionals and students in biotechnology and pharmacology. This book meticulously explores the intersection of biotechnology with drug development, emphasizing its crucial role in creating new therapies for human disease. Central to the book is the innovative use of biotechnology in understanding and treating diseases. It begins with an exploration of multi-omics profiles, shedding light on disease mechanisms and drug development. Subsequent chapters explain in silico methods for drug design, the role of natural products in antimicrobial applications and wound healing, and the use of viruses as carriers in biotechnology. Key features of this reference include a blend of theoretical knowledge and practical insights, detailed analyses of molecular docking in drug discovery, the repurposing of drugs for various diseases, and the emerging field of omics technologies in drug interaction studies. Each chapter is comprehensive, offering current information backed by extensive references, making the book both a foundational and advanced resource. Readership Students and professionals in the fields of biotechnology and pharmacology.