Current and Future Immunosuppressive Therapies Following Transplantation
Current and Future Immunosuppressive Therapies Following Transplantation

Author: Mohamed H. Sayegh

Publisher: Springer Science & Business Media

Published: 2001-09-30

Total Pages: 412

ISBN-13: 9781402000188

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This title provides a comprehensive and state-of-the-art summary of current and future immunosuppressive strategies in transplantation, with emphasis on the basic science mechanisms and clinical applicability of these strategies. The uniqueness of this book is the inclusion of up-to-date information on the basic mechanisms of actions of the immunosuppressive drugs as well as a summary of the clinical trials data and the potential use of these drugs in clinical organ transplantation. In addition to describing the various immunosuppressive strategies, the book has three special features, including immunosuppression in xenotransplantation, gene therapy approaches, and transplantation tolerance. A group of outstanding investigators have been assembled to write the chapters. The book is intended for the transplant professional and the specialist who wants to stay abreast of the current status of immunosuppression in organ transplantation. The book is also useful for basic scientists who work in the field of transplantation immunology.

Truck'n
Truck'n

Author: Loyd Skiles

Publisher: Lulu.com

Published: 2005-07

Total Pages: 284

ISBN-13: 1411640373

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The autobiographical adventures of a rock 'n roll Karma Bandit who hops in a big rig in New York City with his truck driving partner, criss-crossing America twice during a month long run with the President hot on their trail, finally encountering everything from subtrefuge to murder

CB Fry: King Of Sport - England's Greatest All Rounder; Captain of Cricket, Star Footballer and World Record Holder
CB Fry: King Of Sport - England's Greatest All Rounder; Captain of Cricket, Star Footballer and World Record Holder

Author: Iain Wilton

Publisher: Metro Publishing

Published: 2014-08-31

Total Pages: 651

ISBN-13: 184358686X

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Charles Burgess Fry, known as C. B. Fry was an English polymath; an outstanding sportsman, politician, diplomat, academic, teacher, writer, editor and publisher, who is best remembered for his career as a cricketer. Fry's achievements on the sporting field included representing England at both cricket and football, an F.A. Cup Final appearance for Southampton F.C. and equalling the then world record for the long jump. But he was much more than a sportsman. He won a major scholarship to Oxford, where his friends numbered Max Beerbohm, Hilaire Belloc, and F.E. Smith. He wrote several books, including an autobiography and a novel, and he was one of the most successful journalists of his day. He was a friend of many prominent Labour and Liberal politicians, but flirted with Fascism, meeting Hitler in 1934. He tried out for Hollywood, represented India at the League of Nations, and stood for Parliament three times. 'A most incredible man . . . the most variously gifted Englishman of any age . . . the pre-eminent all-rounder, not merely of his own age but, so far as is measurable, of all English history.' John Arlott; 'This is a well-researched, well-rounded picture of one of England's great sporting heroes.' - Jeremy Paxman, Mail on Sunday; 'He has written what should come to be regarded as one of the very best sporting biographies. I could not put it down.' - Michael Kennedy, Sunday Telegraph; 'This is a book that rises to its subject's level in fascination, entertainment and brilliance.' - Tim Rice, Literary Review

Late Graft Loss
Late Graft Loss

Author: J.-L. Touraine

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 325

ISBN-13: 9401154341

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In all varieties of organ transplants, early results have dramatically improved over the past two decades and failures due to acute rejection are becoming rarer. Efficient immunosuppressive regimens have been developed with the objective of very good results at 1, 3 and 5 years. Successful transplants, however, are significantly less frequent at 10 and 20 years, and many patients require retransplantation. Many factors are involved in late graft loss and it is now well recognized that, in addition to chronic rejection, a number of non-immunologic factors play a prominent role. In the case of renal transplantation, a reduced mass loss (transplantation of a single kidney, sometimes from an aged donor, ischemic injury and alteration of some nephrons in the case of early acute rejection) will result in slowly progressing chronic renal failure, even in the absence of any supplementary attack of an immunological nature. The new treatments must be analyzed in the light of their capacity to reduce these late failures. Several preventive measures can also limit both immunologic and non-immunologic factors of late transplant deterioration.

The Art of Peace
The Art of Peace

Author: Juliana Geran Pilon

Publisher: Routledge

Published: 2017-07-05

Total Pages: 414

ISBN-13: 1351485717

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Sun Tzu, author of 'The Art of War', believed that the acme of leadership consists in figuring out how to subdue the enemy with the least amount of fighting a fact that America's Founders also understood, and practiced with astonishing success. For it to work, however, a people must possess both the ability and the willingness to use all available instruments of power in peace as much as in war. US foreign policy has increasingly neglected the instruments of civilian power and become overly dependent on lethal solutions to conflict. The steep rise in unconventional conflict has increased the need for diplomatic and other non-hard power tools of statecraft. The United States can no longer afford to sit on the proverbial three-legged national security stool ("military, diplomacy, development"), where one leg is a lot longer than either of the other two, almost forgetting altogether the fourth leg information, especially strategic communication and public diplomacy. The United States isn't so much becoming militarized as DE civilianized. According to Sun Tzu, self-knowledge is as important as knowledge of one's enemy: "if you know neither yourself nor the enemy, you will succumb in every battle." Alarmingly, the United States is deficient on both counts. And though we can stand to lose a few battles, the stakes of losing the war itself in this age of nuclear proliferation are too high to contemplate.