Activation of Immediate Early Genes by Drugs of Abuse
Author: Reinhard Grzanna
Publisher: Department of Health and Human Services Public Health Servic
Published: 1993
Total Pages: 232
ISBN-13:
DOWNLOAD EBOOKRead and Download eBook Full
Author: Reinhard Grzanna
Publisher: Department of Health and Human Services Public Health Servic
Published: 1993
Total Pages: 232
ISBN-13:
DOWNLOAD EBOOKAuthor: Reinhard Grzanna
Publisher:
Published: 1993
Total Pages: 219
ISBN-13:
DOWNLOAD EBOOKAuthor: L. Kaczmarek
Publisher: Gulf Professional Publishing
Published: 2002-07
Total Pages: 400
ISBN-13: 9780444508355
DOWNLOAD EBOOKThis book brings together information about the most widely studied IEG/ITF involved in a variety of neuronal activation. Written by a prominent group of authors, it attempts to unravel the complexity of the phenomena of gene expression in the central nervous system.
Author: Ronald P. Hammer, Jr.
Publisher: CRC Press
Published: 1995-07-17
Total Pages: 286
ISBN-13: 9780849383113
DOWNLOAD EBOOKRepresenting the latest data from active research groups, The Neurobiology of Cocaine is designed to educate students and inform experts in a rapidly changing field. This volume presents current research regarding the mechanisms of cocaine's action in the brain. Recent developments of cellular, molecular, and brain imaging methods provide new evidence that chemical and molecular substrates underlie cocaine reinforcement, dependence, and withdrawal. This book explores the biological bases of such effects, describing the brain circuits affected by cocaine, neuroendocrine and neurophysiological actions of cocaine, neurochemistry and pharmacology of cocaine, and cocaine effects on signal transduction, gene expression, and protein phosphorylation. This up-to-date text also describes the recently cloned class of neurotransporters affected by cocaine and characterizes their interaction with the drug. These reports focus on the effects of chronic exposure and subsequent withdrawal, which are differentiated from acute cocaine actions. Thus, they provide information on brain mechanisms likely active during long-term use and abuse in humans. Such commonalities are illustrated by a discussion of cocaine action in the human brain as visualized by positron emission tomography. This volume is a must for anyone interested in the mechanisms underlying cocaine abuse.
Author:
Publisher:
Published: 1991
Total Pages: 248
ISBN-13:
DOWNLOAD EBOOKAuthor: Harold W. Gordon
Publisher: DIANE Publishing
Published: 1997-07
Total Pages: 363
ISBN-13: 0788146084
DOWNLOAD EBOOKProvides a platform of ideas from which new directions for research in the behavioral etiology of substance abuse can be developed. Researchers from a variety of neurobiological disciplines present proposals on innovative ways to study and understand individual differences in neurobiological risk and resistance factors for drug abuse. The focus of these proposals is in three areas: genetic bases, neurophysiological correlates, and neurochemical factors underlying drug abuse risk or resistance. Tables, graphs and references.
Author: Jerry J. Buccafusco
Publisher: CRC Press
Published: 2000-08-29
Total Pages: 341
ISBN-13: 1420041819
DOWNLOAD EBOOKUsing the most well-studied behavioral analyses of animal subjects to promote a better understanding of the effects of disease and the effects of new therapeutic treatments on human cognition, Methods of Behavior Analysis in Neuroscience provides a reference manual for molecular and cellular research scientists in both academia and the pharmaceutic
Author:
Publisher:
Published: 1994
Total Pages: 228
ISBN-13:
DOWNLOAD EBOOKAuthor: Robert A. Weinberg
Publisher: Garland Science
Published: 2013-05-15
Total Pages: 960
ISBN-13: 1317963466
DOWNLOAD EBOOKThoroughly updated and incorporating the most important advances in the fast-growing field of cancer biology, The Biology of Cancer, Second Edition, maintains all of its hallmark features admired by students, instructors, researchers, and clinicians around the world.The Biology of Cancer is a textbook for students studying the molecular and cellula
Author: John Q. Wang
Publisher: Springer Science & Business Media
Published: 2008-02-01
Total Pages: 500
ISBN-13: 1592593585
DOWNLOAD EBOOKDrugs of Abuse: Neurological Reviews and Protocols is intended to provide insightful reviews of key current topics and, particularly, state-- the-art methods for examining drug actions in their various neuroanato- cal, neurochemical, neurophysiological, neuropharmacological, and molecular perspectives. The book should prove particularly useful to n- comers (graduate students and technicians) in this field, as well as to those established scientists (neuroscientists, biochemists, and molecular biologists) intending to pursue new careers or directions in the study of drugs. The book’s protocols cover a wide variety of coherent methods for gathering inf- mation on quantitative changes in proteins and mRNAs at both tissue and cel- lar levels. Inducible gene expression in striatal neurons has been a hot topic over the last decade. Alterations in gene expression for a wide range of proteins in the striatum have been investigated in response to drug administration. Altered expression of given mRNAs and their product proteins constitutes essential molecular steps in the development of neuroplasticity related to long-term addictive properties of drugs of abuse. With the multiple labeling methods that are also described in the book, gene expression can be detected in a chemically identified cell phenotype; the expression of multiple genes of interest can be detected in a single cell simultaneously. Hundreds or thousands of gene expr- sion products can today be detected in one experimental setup using the pow- ful systematic cDNA macroarray or microarray screening technology. Moreover, protocols useful in analyzing the functional roles of genes and proteins (e. g.