A new theory of the living cell, the association-induction hypothesis, has been proposed. This book examines this revolution in cell physiology which has successfully withstood 25 years of world-wide testing. It has already generated magnetic resonance imaging (MRI).
"...This volume is presented as a story or history starting from the moment Mankind began to peek into the microscopic world of cells and microbes with the invention of microscopes-and even earlier, much earlier-continuing through landmark events of false starts and new insights put away for the wrong reasons etc., etc., culminating in the association-induction hypothesis of today."--vii.
It is highly probable that the ability to distinguish between living and nonliving objects was already well developed in early prehuman animals. Cognizance of the difference between these two classes of objects, long a part of human knowledge, led naturally to the division of science into two categories: physics and chemistry on the one hand and biology on the other. So deep was this belief in the separateness of physics and biology that, as late as the early nineteenth century, many biologists still believed in vitalism, according to which living phenomena fall outside the confines of the laws of physics. It was not until the middle of the nineteenth century that Carl Ludwig, Hermann von Helmholz, Emil DuBois-Reymond, and Ernst von Briicke inaugurated a physicochem ical approach to physiology in which it was recognized clearly that one set of laws must govern the properties and behavior of all matter, living and nonliving . . The task of a biologist is like trying to solve a gigantic multidimensional crossword fill in the right physical concepts at the right places. The biologist depends on puzzle: to the maturation of the science of physics much as the crossword solver depends on a large and correct vocabulary. The solver of crossword puzzles needs not just a good vocabulary but a special vocabulary. Words like inee and oke are vitally useful to him but are not part of the vocabulary of an English professor.
Physical Biology of the Cell is a textbook for a first course in physical biology or biophysics for undergraduate or graduate students. It maps the huge and complex landscape of cell and molecular biology from the distinct perspective of physical biology. As a key organizing principle, the proximity of topics is based on the physical concepts that
Elegant, suggestive, and clarifying, Lewis Thomas's profoundly humane vision explores the world around us and examines the complex interdependence of all things. Extending beyond the usual limitations of biological science and into a vast and wondrous world of hidden relationships, this provocative book explores in personal, poetic essays to topics such as computers, germs, language, music, death, insects, and medicine. Lewis Thomas writes, "Once you have become permanently startled, as I am, by the realization that we are a social species, you tend to keep an eye out for the pieces of evidence that this is, by and large, good for us."
"As someone who has spent forty years in psychology with a long-standing interest in evolution, I'll just assimilate Howard Bloom's accomplishment and my amazement."-DAVID SMILLIE, Visiting Professor of Zoology, Duke University In this extraordinary follow-up to the critically acclaimed The Lucifer Principle, Howard Bloom-one of today's preeminent thinkers-offers us a bold rewrite of the evolutionary saga. He shows how plants and animals (including humans) have evolved together as components of a worldwide learning machine. He describes the network of life on Earth as one that is, in fact, a "complex adaptive system," a global brain in which each of us plays a sometimes conscious, sometimes unknowing role. and he reveals that the World Wide Web is just the latest step in the development of this brain. These are theories as important as they are radical. Informed by twenty years of interdisciplinary research, Bloom takes us on a spellbinding journey back to the big bang to let us see how its fires forged primordial sociality. As he brings us back via surprising routes, we see how our earliest bacterial ancestors built multitrillion-member research and development teams a full 3.5 billion years ago. We watch him unravel the previously unrecognized strands of interconnectedness woven by crowds of trilobites, hunting packs of dinosaurs, feathered flying lizards gathered in flocks, troops of baboons making communal decisions, and adventurous tribes of protohumans spreading across continents but still linked by primitive forms of information networking. We soon find ourselves reconsidering our place in the world. Along the way, Bloom offers us exhilarating insights into the strange tricks of body and mind that have organized a variety of life forms: spiny lobsters, which, during the Paleozoic age, participated in communal marching rituals; and bees, which, during the age of dinosaurs, conducted collective brainwork. This fascinating tour continues on to the sometimes brutal subculture wars that have spurred the growth of human civilization since the Stone Age. Bloom shows us how culture shapes our infant brains, immersing us in a matrix of truth and mass delusion that we think of as reality. Global Brain is more than just a brilliantly original contribution to the ongoing debate on the inner workings of evolution. It is a "grand vision," says the eminent evolutionary biologist David Sloan Wilson, a work that transforms our very view of who we are and why.
The most misunderstood force driving health and disease The story of the invention and use of electricity has often been told before, but never from an environmental point of view. The assumption of safety, and the conviction that electricity has nothing to do with life, are by now so entrenched in the human psyche that new research, and testimony by those who are being injured, are not enough to change the course that society has set. Two increasingly isolated worlds--that inhabited by the majority, who embrace new electrical technology without question, and that inhabited by a growing minority, who are fighting for survival in an electrically polluted environment--no longer even speak the same language. In The Invisible Rainbow, Arthur Firstenberg bridges the two worlds. In a story that is rigorously scientific yet easy to read, he provides a surprising answer to the question, "How can electricity be suddenly harmful today when it was safe for centuries?"
This unique proceedings volume offers one of the very first truly interdisciplinary conferences ever organized. More than 15 papers in this volume are written by some of the most acclaimed researchers in their field. Contributions range over a very wide spectrum of disciplines: biology; computer science; economics; education; health sciences; operations research; philosophy; physics; psychology; mathematics; music and sociology.
This book focuses on the mechanical properties of cells, discussing the basic concepts and processes in the fields of immunology, biology, and biochemistry. It introduces and explains state-of-the-art biophysical methods and examines the role of mechanical properties in the cell/protein interaction with the connective tissue microenvironment. The book presents a unique perspective on cellular mechanics and biophysics by combining the mechanical, biological, physical, biochemical, medical, and immunological views, highlighting the importance of the mechanical properties of cells and biophysical measurement methods. The book guides readers through the complex and growing field of cellular mechanics and biophysics, connecting and discussing research findings from different fields such as biology, cell biology, immunology, physics, and medicine. Featuring suggestions for further reading throughout and addressing a wide selection of biophysical topics, this book is an indispensable guide for graduate and advanced undergraduate students in the fields of cellular mechanics and biophysics.
Advances in fluorescent proteins, live-cell imaging, and superresolution instrumentation have ushered in a new era of investigations in cell biology, medicine, and physiology. From the identification of the green fluorescent protein in the jellyfish Aequorea victoria to the engineering of novel fluorescent proteins, The Fluorescent Protein Revoluti