This book, “”A Practical Book of Pharmaceutical Organic Chemistry-II,”” was written by 07 different authors in accordance with the B.Pharm thirds-semester PCI curriculum. The primary purpose of this book is to provide readily accessible methods and procedures for conducting pharmaceutical Organic chemistry practicals in the 3rd semester of B. Pharm, with a focus on facilitating subject comprehension. It contains 17 experiments based strictly on the PCI curriculum containing introductory part on Recrystallisation and Steam distillation technique, following by experimental procedures of various organic compounds mentioned in the PCI Syllbus ”
The second edition of the book continues to offer a range of pedagogical features maintaining the balanced approach of the text. The attempts have been made to further strengthen the conceptual understanding by introducing more ideas and a number of solved problems. Comprehensive in approach, this text presents a rigorous treatment of organic chemistry to enable undergraduate students to learn the subject in a clear, direct, easily understandable and logical manner. Presented in a new and exciting way, the goal of this book is to make the study of organic chemistry as stimulating, interesting, and relevant as possible. Beginning with the structures and properties of molecules, IUPAC nomenclature, stereochemistry, and mechanisms of organic reactions, proceeding next to detailed treatment of chemistry of hydrocarbons and functional groups, then to organometallic compounds and oxidation–reduction reactions, and ending with a study of selected topics (such as heterocyclic compounds, carbohydrates, amino acids, peptides and proteins, drugs and pesticides, dyes, synthetic polymers and spectroscopy), the book narrates a cohesive story about organic chemistry. Transitions between topics are smooth, explanations are lucid, and tie-ins to earlier material are frequent to maintain continuity. The book contains over 500 solved problems from simple to really challenging ones with suitable explanations. In addition, over 275 examples and solved problems on IUPAC nomenclature, with varying levels of difficulty, are included. About Some Key Features of the Book • EXPLORE MORE: Four sets of solved problems provide in-depth knowledge and enhanced understanding of some important aspects of organic chemistry. • MINI ESSAYS: Three small essays present interesting write-ups to provide students with introductory knowledge of chemistry of natural products such as lipids, terpenes, alkaloids, steroids along with nucleic acids and enzymes. • NOTABILIA: Twenty-two ‘notabilia boxes’ interspersed throughout the text highlight the key aspects of related topics, varying from concepts of chemistry to the chemistry related to day-to-day life. • STRUCTURES AND MECHANISMS NOT IN ORDER: Cites examples of common errors made by students while drawing structural formulae and displaying arrows in reaction mechanisms and helps them to improve on language of organic chemistry by teaching appropriate drawings and their significance. • GLOSSARY: Includes ‘Name reactions’, ‘Reagents’, and some important terms for quick revision by students. Clearly written and logically organized, the authors have endeavoured to make this complex and important branch of science as easy as possible for students to learn from and for teachers to teach from.
Pharmaceutical organic chemistry is the main branch of organic chemistry deals with the study of preparation, structure and reactions of organic compounds. As it deals with all the chemical reactions related to life, study of Pharmaceutical organic chemistry is important. Application of Organic chemistry in the development of pharmaceuticals, resulted in evolving Pharmaceutical organic chemistry. Hence studying Organic chemistry and applying this knowledge in Pharmaceutical substances is called as Pharmaceutical organic chemistry. Organic chemistry forms the basis of biochemistry, in which various aspects of health and diseases are studied. The biochemical knowledge is very important for the practice of nutritional, medical and related life sciences. In addition Organic chemistry paved way for the development of medicinal chemistry, Pharmaceutical organic chemistry, bioinformatics, biotechnology, gene therapy, Pharmacology, pathology, chemical engineering, dental science and so on. Organic substances play such a vital role in our daily life that all of us should know about organic chemistry in order to understand the manner how it influence our life process.
This book is designed to provide a basic introduction to some of the most significant topics in organic chemistry, with an emphasis on the chemistry of polynuclear hydrocarbons, cycloalkanes, phenols, aromatic amines, aromatic acids, fats and oils, and benzene and its derivatives. From the basic structure and reactivity of benzene to the study of complex organic compounds, the material is arranged to lead readers through a logical progression of themes. Every course aims to provide students a thorough theoretical grasp as well as useful insights into the chemical behaviors and practical uses of these substances. Important reactions, analytical techniques, and the practical relevance of the compounds under discussion are all given particular attention. This book tries to make difficult subjects approachable and interesting for experts, teachers, and students alike via thorough explanations and pertinent examples. I hope that anybody looking to learn more about organic chemistry will find this book to be a useful resource, and that it will stimulate further research and investigation in this exciting area.
This book is a hands-on guide for the organic chemist. Focusing on the most reliable and useful reactions, the chapter authors provide the information necessary for a chemist to strategically plan a synthesis, as well as repeat the procedures in the laboratory. Consolidates all the key advances/concepts in one book, covering the most important reactions in organic chemistry, including substitutions, additions, eliminations, rearrangements, oxidations, reductions Highlights the most important reactions, addressing basic principles, advantages/disadvantages of the methodology, mechanism, and techniques for achieving laboratory success Features new content on recent advances in CH activation, photoredox and electrochemistry, continuous chemistry, and application of biocatalysis in synthesis Revamps chapters to include new and additional examples of chemistry that have been demonstrated at a practical scale
A hands-on guide to assist in the planning and execution of synthetic reactions in the laboratory Despite the maturity of organic chemistry, it can still be very challenging to identify optimal methods for synthetic transformations that perform as well in real-world manufacturing processes as they do in the laboratory. This detailed and accessible guide attempts to address this vexing issue and deliver proven methodologies practicing synthetic chemists will find valuable for identifying reaction conditions that work reliably over the broadest possible range of substrates. Practical Synthetic Organic Chemistry: Provides a practical guide to strategically planning and executing chemical syntheses for the bench chemist in industry Discusses information that is not common knowledge beyond the boundaries of process chemistry groups, such as the synthetic routes of selected contemporary pharmaceutical drugs and practical solvents, as well as green chemistry concepts Highlights key reactions, including substitutions, additions, eliminations, rearrangements, oxidations, and reductions Addresses basic principles, mechanisms, advantages and disadvantages of the methodology, and techniques for achieving laboratory success Incorporating such an extraordinary wealth of information on organic chemistry and its related fields into one complete volume distinguishes Practical Synthetic Organic Chemistry as an incomparable desktop reference for professionals and an invaluable study aid for students.
: Pharmaceutical organic chemistry is an important part of Pharmaceutical Research and Development unit, since it involves preparation of novel or modification of already existing molecules to extract the therapeutic application of these molecules. This book deals with different types of experiments, where the major emphasis is given on various basic techniques of Organic chemistry like melting point, boiling point, crystallization, distillation, and calibration of thermometer. It also includes identification of organic compound of various functional groups from carboxylic acid, Phenols, ketons, aldehyde….etc, with specific reaction procedure and its chemical reaction. It also covers experimental methods consisting of the derivatives preparations of functional groups. The book also covers some Organic preparation /Synthesis of compounds with reaction, principle and mechanism These experiments are selected in such a manner that the reader should get a in depth knowledge about the medicinal chemistry practicals. All comments and suggestions will be received with gratitude. I am very much grateful to KLE Academy of Higher Education and Research, all my beloved teachers, parents, wife for their constant support and encouragement. Thanks to my daughters Ananya and Adhya, who are my stress relievers. I would like to express my heartfelt thanks to each and everyone who directly or indirectly helped me in compilation of this book Last but not the least I am very much thankful to all my students who are the inspiration for writing this book.
