Friedrich Schleiermacher’s Pathways of Translation
Friedrich Schleiermacher’s Pathways of Translation

Author: Piotr de Bończa Bukowski

Publisher: Walter de Gruyter GmbH & Co KG

Published: 2023-01-30

Total Pages: 343

ISBN-13: 3110745542

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This interdisciplinary study introduces readers to Friedrich Schleiermacher’s diverse pathways of reflection and creative practice that are related to the field of translation. By drawing attention to Schleiermacher’s various writings on a range of subjects (including philology, criticism, hermeneutics, dialectics, rhetoric and religion), the author makes it clear that the frequently cited lecture Über die verschiedenen Methoden des Übersetzens (On the Different Methods of Translating) represents but a fraction of Schleiermacher’s contributions to modern-day insights into translation. The analysis of Schleiermacher’s various pathways of reflection on translation presented in this book leads to the conclusion that translation is part of the essence of the world, as it is a fundamental tool of our cognition and a foundation of our existence. In Schleiermacher’s works, transfer, translation, mediation, and communication underpin our very existence in the world and our self-awareness. At the same time, they represent fundamental categories for a project that focuses on the consolidation and assimilation – through translation – of that which is foreign, different, diverse.

Pathway Analysis for Drug Discovery
Pathway Analysis for Drug Discovery

Author: Anton Yuryev

Publisher: John Wiley & Sons

Published: 2008-09-17

Total Pages: 332

ISBN-13: 0470399260

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This book introduces drug researchers to the novel computational approaches of pathway analysis and explains the existing applications that can save time and money in the drug discovery process. It covers traditional computational methods and software for pathway analysis microarray, proteomics, and metabolomics. It explains pathway reconstruction of diseases and toxic states, pathway analysis in various phases, dynamic modeling of drug responses, and more. This is a core resource for drug discovery and pharmaceutical industry researchers, chemists, and biologists and for professionals in related fields.

Computational Methods for Processing and Analysis of Biological Pathways
Computational Methods for Processing and Analysis of Biological Pathways

Author: Anastasios Bezerianos

Publisher: Springer

Published: 2017-03-09

Total Pages: 96

ISBN-13: 3319538683

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This work offers a guided walkthrough of one of the most promising research areas in modern life sciences, enabling a deeper understanding of involved concepts and methodologies via an interdisciplinary view, focusing on both well-established approaches and cutting-edge research. Highlighting what pathway analysis can offer to both the experimentalist and the modeler, the text opens with an introduction to a general methodology that outlines common workflows shared by several methods. This is followed by a review of pathway and sub-pathway based approaches for systems pharmacology. The work then presents an overview of pathway analysis methods developed to model the temporal aspects of drug- or disease-induced perturbations and extract relevant dynamic themes. The text concludes by discussing several state-of-the-art methods in pathway analysis, which address the important problem of identifying differentially expressed pathways and sub-pathways.

Verification, Model Checking, and Abstract Interpretation
Verification, Model Checking, and Abstract Interpretation

Author: Neil D. Jones

Publisher: Springer Science & Business Media

Published: 2009-02-13

Total Pages: 392

ISBN-13: 3540938990

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The book constitutes the refereed proceedings of the 10th International Conference on Verification, Model Checking, and Abstract Interpretation, VMCAI 2009, held in Savannah, GA, USA, in January 2009 - co-located with POPL 2009, the 36th Annual Symposium on Principles of Programming Languages. The 24 revised full papers presented together with 3 invited talks and 2 invited tutorials were carefully reviewed and selected from 72 submissions. The papers address all current issues from the communities of verification, model checking, and abstract interpretation, facilitating interaction, cross-fertilization, and advancement of hybrid methods that combine the three areas.

Pathway Analysis and Optimization in Metabolic Engineering
Pathway Analysis and Optimization in Metabolic Engineering

Author: Néstor V. Torres

Publisher: Cambridge University Press

Published: 2002-12-19

Total Pages: 328

ISBN-13: 9781139437615

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Facility in the targeted manipulation of the genetic and metabolic composition of organisms, combined with unprecedented computational power, is forging a niche for a new subspecialty of biotechnology called metabolic engineering. First published in 2002, this book introduces researchers and advanced students in biology and engineering to methods of optimizing biochemical systems of biotechnological relevance. It examines the development of strategies for manipulating metabolic pathways, demonstrates the need for effective systems models, and discusses their design and analysis, while placing special emphasis on optimization. The authors propose power-law models and methods of biochemical systems theory toward these ends. All concepts are derived from first principles, and the text is richly illustrated with numerous graphs and examples throughout. Special features include: nontechnical and technical introductions to models of biochemical systems; a review of basic methods of model design and analysis; concepts of optimization; and detailed case studies.

A Biblical Path to the Triune God
A Biblical Path to the Triune God

Author: Denis M. Farkasfalvy

Publisher:

Published: 2021

Total Pages:

ISBN-13: 9780813234762

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"This short volume was finished just before Denis Farkasfalvy's death in 2020. Farkasfalvy aimed to reconcile and unite theological disciplines that had increasingly become isolated from each other, most notably the biblical, patristic, and systematic. In A Biblical Path to the Triune God, the Cistercian abbot identifies the earliest biblical witnesses to the Church's teaching about God as Father, Son, and Holy Spirit. This book aims to show that the Trinitarian doctrine of the Church defined in the later ecumenical councils is firmly rooted in the very first reflections on Jesus' ministry and mystery by the biblical authors"--

Metabolic Structure and Regulation
Metabolic Structure and Regulation

Author: Raymond S. Ochs

Publisher: CRC Press

Published: 2017-12-14

Total Pages: 284

ISBN-13: 1482236095

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There is a renewed interest in the fundamentals of energy metabolism, yet most people base their understanding on the views of generalists expressed in elementary textbooks. New techniques that enable analysis of thousands of metabolites provide useful data, but do not themselves substitute for an understanding of the fundamentals of metabolism. While classical ideas of metabolism are also valuable, some earlier ideas have not withstood further investigation. This book presents a personal philosophy but rests on what is broadly accepted by metabolic biochemists over the past few decades.

Discourse Analysis Beyond the Speech Event
Discourse Analysis Beyond the Speech Event

Author: Stanton Wortham

Publisher: Routledge

Published: 2020-11-29

Total Pages: 182

ISBN-13: 100024525X

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In its first edition, winner of the 2016 Edward Sapir Book Prize from the Society for Linguistic Anthropology of the American Anthropological Association Discourse Analysis Beyond the Speech Event introduces a new approach to discourse analysis. In this innovative work, Wortham and Reyes argue that discourse analysts should look beyond fixed speech events and consider the development of discourses over time. Drawing on theories and methods from linguistic anthropology and related fields, this book is the first to present a systematic methodological approach to conducting discourse analysis of linked events, allowing researchers to understand not only individual events but also the patterns that emerge across them. This new edition: Draws on theories and methods from linguistic anthropology and related fields; Presents the first systematic methodological approach to doing discourse analysis of linked events; Provides easy-to-use tools and techniques for analyzing discourse both within and across events; Offers transparent procedures and clear illustrations to show how the approach can be applied to analyze three types of data: ethnographic, archival, and new media; Includes a new chapter focusing on the discourse analysis of contemporary nationalist new media data. Updated and revised for the second edition, this book is essential reading for advanced students and researchers working in the area of discourse analysis.

Neuroimaging of Pain
Neuroimaging of Pain

Author: Luca Saba

Publisher: Springer

Published: 2017-06-08

Total Pages: 509

ISBN-13: 3319480464

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Authored by world renowned scientists, this book expertly reviews all the imaging techniques and exciting new methods for the analysis of the pain, including novel tracers, biomarker, metabolomic and gene-array profiling, together with cellular, genetic, and molecular approaches. Recent advances in human brain imaging techniques have allowed a better understand of the functional connectivity in pain pathways, as well as the functional and anatomical alterations that occur in chronic pain patients. Modern imaging techniques have permitted rapid progress in the understanding of networks in the brain related to pain processing and those related to different types of pain modulation. Neuroimaging of Pain is designed to be a valuable resource for radiologists, neuroradiologists, neurologists and neuroscientists, working in hospitals and universities from junior trainees to consultants.

Marine Omics in a Changing Ocean: Modelling Molecular Pathways and Networks to Understand Species Acclimation and Adaptation
Marine Omics in a Changing Ocean: Modelling Molecular Pathways and Networks to Understand Species Acclimation and Adaptation

Author: Carolina Madeira

Publisher: Frontiers Media SA

Published: 2024-07-08

Total Pages: 150

ISBN-13: 2832551513

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Global climate change is a major threat to marine biodiversity worldwide. Average changes in ocean temperature, pH, and oxygenation are re-shaping marine communities, with significant impacts on the critical services that marine ecosystems provide to mankind. As global climate change continues, the frequency, duration, and intensity of extreme weather events are also predicted to increase, with fast and far-reaching consequences on marine species, including mass mortality and disruption of ecological processes. As a result, millions of ocean-dependent livelihoods and jobs are also at risk, with consequent economic impacts. Given the current climate and biodiversity crisis, the Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services has emphasized the relevance of (1) increasing knowledge and protection of biodiversity and (2) assessing species climate-driven extinction risks. To achieve these goals, we need to understand organism-environment-ecology-evolution interactions at various levels of the biological hierarchy, from molecules to ecosystems. However, we are still lacking a comprehensive understanding of the molecular mechanisms shaping phenotypic landscapes in the natural environment, and under different global change scenarios. To address such challenges, a new strategic program was also launched by the European Molecular Biology Laboratory (EMBL), “Molecules to Ecosystems”, to study life in context, and provide new research avenues in molecular life sciences. In this context, the emerging disciplines of Marine Omics and Marine Systems Biology will be key to supporting innovative solutions in marine ecosystem conservation and blue bioeconomy (for example uncover molecular traits underlying sensitivity/tolerance to environmental change, supporting assisted evolution approaches; molecular targets that can be used for diagnostics, monitoring and development of biotechnological applications).