A Guide to Living with Von Willebrand Disease

A Guide to Living with Von Willebrand Disease

Author: Laureen Kelley

Publisher:

Published: 2021-08

Total Pages:

ISBN-13: 9781938851100

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The world's first book on the world's most commonly inherited bleeding disorder. Topics include learning to cope with VWD, inheritance, the medical system, treatment, women's issues, health insurance. Complete resource guide and real-life stories.


Hemophilia and Von Willebrand Disease

Hemophilia and Von Willebrand Disease

Author: David Green

Publisher: Academic Press

Published: 2018-06-14

Total Pages: 286

ISBN-13: 0128129557

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Hemophilia and Von Willebrand Disease: Factor VIII and Von Willebrand Factor serves as a must-have reference on the important role these essential blood-clotting proteins play in research and clinical medicine. Clinicians and researchers face the daily challenge of staying current on the vast amounts of research that is now generated. The reference to Janus in the title refers to the two roles of the Factor VIII/Von Willebrand Factor Complex: initiation of coagulation and propagation of clot formation. The complex prevents bleeding in hemophilia and Von Willebrand disease but also augments arterial and venous thrombosis. Presents one source of information on Hemophilia and Von Willebrand Disease, as well as Factor VIII and Von Willebrand Factor, eliminating the search through hundreds of journal articles Combines the multi-disciplinary research that is generated from Factor VIII/Von Willebrand Factor – hematology, drug discovery, genetics, cell biology, and oncology Delves into unanswered questions and future directions of this important blood-clotting complex


Ehlers-Danlos Syndrome: A Multidisciplinary Approach

Ehlers-Danlos Syndrome: A Multidisciplinary Approach

Author: J.W.G. Jacobs

Publisher: IOS Press

Published: 2018-08-14

Total Pages: 370

ISBN-13: 1614998787

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Generalized hypermobility has been known since ancient times, and a clinical description of Ehlers-Danlos syndrome (EDS) is said to have first been recorded by Hippocrates in 400 BC. Hypermobility syndromes occur frequently, but the wide spectrum of possible symptoms, coupled with a relative lack of awareness and recognition, are the reason that they are frequently not recognized, or remain undiagnosed. This book is an international, multidisciplinary guide to hypermobility syndromes, and EDS in particular. It aims to create better awareness of hypermobility syndromes among health professionals, including medical specialists, and to be a guide to the management of such syndromes for patients and practitioners. It is intended for use in daily clinical practice rather than as a reference book for research or the latest developments, and has been written to be understandable for any healthcare worker or educated patient without compromise to the scientific content. The book is organized as follows: chapters on classifications and genetics are followed by chapters on individual types, organ (system) manifestations and complications, and finally ethics and therapeutic strategies, with an appendix on surgery and the precautions which should attend it. A special effort has been made to take account of the perspective of the patient; two of the editors have EDS. The book will be of interest to patients with hypermobility syndromes and their families, as well as to all those healthcare practitioners who may encounter such syndromes in the course of their work.


Handbook of Gynecology

Handbook of Gynecology

Author: Donna Shoupe

Publisher: Springer Nature

Published: 2024-01-07

Total Pages: 1295

ISBN-13: 3031148819

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This book is a comprehensive, up-to-date reference on general and subspecialty gynecology. Covering all aspects of gynecology commonly encountered in day-to-day practice, this exhaustive and fully updated new edition provides a practical, one-stop reference work for clinicians working in the field. This carefully-designed volume includes ten sections, beginning with comprehensive coverage of office-based gynecology, and continuing on to present disease processes and management information by patient age group. Each chapter includes background information, current recommendations for screening, diagnostic criteria, common and uncommon associated problems, approach to diagnosis, summary of treatment options, and an overview of ICD-10 codes for specific diagnoses. Importantly, many areas that are covered in the handbook as subspecialty problems are pertinent and important information to many of the general practitioners who handle and develop some expertise in these areas. These include ovulation induction, medical management of incontinence, management of abnormal Pap smears, and work-up of abnormal bleeding. The handbook concludes with an easy-to-navigate presentation of minimally-invasive operations, surgical procedures, neoplasms, and pathology. Advantages and risks associated with management of particular diseases are covered, along with multiple tips for avoiding complications. This second edition is fully updated. With extensive updates on cervical cancer screening, pelvic organ prolapse, and more, many chapters will be completely rewritten to reflect the latest guidelines, procedures, and methods of care in women’s health. The text additionally includes two new chapters, covering the impact of COVID on gynecology care, and the work-up and surgical management of chronic pelvic pain. This is an ideal guide for practicing gynecologists, family and internal medicine physicians, physician assistants, nurse practitioners, fellows, residents, medical students, and all women’s health care providers.


Congenital Bleeding Disorders

Congenital Bleeding Disorders

Author: Akbar Dorgalaleh

Publisher: Springer

Published: 2018-07-25

Total Pages: 397

ISBN-13: 3319767232

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This book describes in detail the clinical presentation, diagnosis, and management of a wide range of congenital bleeding disorders. It will assist readers in overcoming the significant challenges involved in clinical and laboratory diagnosis and in providing effective clinical care that makes optimal use of new products, including recombinant factor concentrate. The coverage ranges from hemophilia A and B and von Willebrand disease to rare bleeding disorders such as congenital factor V, factor X, factor XI, and factor XIII deficiency and inherited platelet function disorders. The exceptional attention to rarer conditions is of particular importance given the considerable risk of overlooking them during diagnosis, with potential consequences for disease-related morbidity and mortality. The authors are acknowledged specialists in the field from across the world who have particular expertise in the disorder that they discuss. The book will be of value to hematologists, oncologists, pediatricians, laboratory specialists and technicians, general physicians, and trainees.


The Iron Disorders Institute Guide to Anemia

The Iron Disorders Institute Guide to Anemia

Author: Cheryl Garrison

Publisher: Sourcebooks, Inc.

Published: 2009-06-01

Total Pages: 498

ISBN-13: 1402247524

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Unravel the mysteries behind anemia's diverse forms, from iron deficiency anemia to hemolytic and aplastic anemia, and gain a deep understanding of their underlying mechanisms. Empower yourself with the treatments and prevention strategies, carefully curated by the Iron Disorders Institute. Inside these pages, you'll find: Comprehensive explanations of different types of anemia, their prevalence, and risk factors. An in-depth exploration of iron metabolism, absorption, and utilization in the body. Expert advice on diagnosing anemia accurately, distinguishing its various forms, and addressing related health concerns. Essential dietary guidelines and supplementation recommendations to combat iron deficiency and optimize iron levels. Practical tips on managing anemia-related symptoms, such as fatigue, weakness, and shortness of breath, to enhance your overall well-being. Empower yourself with the knowledge to promote healing, vitality, and a healthier life.


Hemostasis and Thrombosis

Hemostasis and Thrombosis

Author: Victor J. Marder

Publisher: Lippincott Williams & Wilkins

Published: 2012-12-27

Total Pages: 5220

ISBN-13: 1451177690

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Since publication of the First Edition in 1982, Hemostasis and Thrombosis has established itself as the pre-eminent book in the field of coagulation disorders. No other book is as inclusive in scope, with coverage of the field from the standpoint of both basic scientists and clinicians. This comprehensive resource details the essentials of bleeding and thrombotic disorders and the management of patients with these and related problems, and delivers the most up-to-date information on normal biochemistry and function of platelets or endothelial cells, as well as in-depth discussions of the pharmacology of anticoagulant, fibrinolytic, and hemostatic drugs. NEW to the Sixth Edition... • A new team of editors, each a leader in his field, assures you of fresh, authoritative perspectives. • Full color throughout • A companion website that offers full text online and an image bank. • A new introductory section of chapters on basic sciences as related to the field • Entirely new section on Hemostatic and Thrombotic Disorders Associated with Systemic Conditions includes material on pediatric patients, women's health issues, cancer, sickle cell disease, and other groups. • Overview chapters preceding each section address broad topics of general importance. This is the tablet version which does not include access to the supplemental content mentioned in the text.


Heart and Toxins

Heart and Toxins

Author: Dr. Meenakshisundaram Sundaram Ramachandran

Publisher: Elsevier

Published: 2014-08-12

Total Pages: 668

ISBN-13: 0124165990

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The Heart and Toxins brings together global experts to provide the latest information and clinical trials that make the connection between genetic susceptibility, gene expression, and environmental factors in cardiovascular diseases. This unique reference, edited by renowned cardiologist Meenakshi Sundaram Ramachandran, solves the problem of managing multiple clinical cases of cardiovascular toxicity. It allows connections to be made between research, diagnosis, and treatment to avoid higher morbidity and mortality rates as a result of cardiovascular toxicity. - Structured to bring together exploration into the epidemiology, molecular mechanism, pathogenesis, environmental factors and management in cardiovascular toxins - Included various topics on cardiovascular toxins such as plant, chemical, animal, nanomaterial and marine biology induced cardiac damage – which are new ideas discussed in detail - Comprehensive chapters on the cardiovascular toxicity from drugs, radiotherapy and radiological imaging - Enables you to manage multiple clinical cases of cardiovascular toxicity - Outlined conclusions at the end of each chapter providing "key learning points to help you organize the chapter's details without losing insight


Raising a Child with Hemophilia

Raising a Child with Hemophilia

Author: Laureen Kelley

Publisher:

Published: 2016-04-01

Total Pages:

ISBN-13: 9781938851056

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A parenting book covering medical, consumer, emotional and practical child-rearing aspects of raising a child with hemophilia.


A Guide to Human Gene Therapy

A Guide to Human Gene Therapy

Author: Roland W. Herzog

Publisher: World Scientific

Published: 2010

Total Pages: 415

ISBN-13: 9814280917

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1. Non-viral gene therapy / Sean M. Sullivan -- 2. Adenoviral vectors / Stuart A. Nicklin and Andrew H. Baker -- 3. Retroviral vectors and integration analysis / Cynthia C. Bartholomae [und weitere] -- 4. Lentiviral vectors / Janka Matrai, Marinee K.L. Chuah and Thierry VandenDriessche -- 5. Herpes simplex virus vectors / William F. Goins [und weitere] -- 6. Adeno-Associated Viral (AAV) vectors / Nicholas Muzyczka -- 7. Regulatory RNA in gene therapy / Alfred. S. Lewin -- 8. DNA integrating vectors (Transposon, Integrase) / Lauren E. Woodard and Michele P. Calos -- 9. Homologous recombination and targeted gene modification for gene therapy / Matthew Porteus -- 10. Gene switches for pre-clinical studies in gene therapy / Caroline Le Guiner [und weitere] -- 11. Gene therapy for central nervous system disorders / Deborah Young and Patricia A. Lawlor -- 12. Gene therapy of hemoglobinopathies / Angela E. Rivers and Arun Srivastava -- 13. Gene therapy for primary immunodeficiencies / Aisha Sauer, Barbara Cassani and Alessandro Aiuti -- 14. Gene therapy for hemophilia / David Markusic, Babak Moghimi and Roland Herzog -- 15. Gene therapy for obesity and diabetes / Sergei Zolotukhin and Clive H. Wasserfall -- 16. Gene therapy for Duchenne muscular dystrophy / Takashi Okada and Shin'ichi Takeda -- 17. Cancer gene therapy / Kirsten A.K. Weigel-Van Aken -- 18. Gene therapy for autoimmune disorders / Daniel F. Gaddy, Melanie A. Ruffner and Paul D. Robbins -- 19. Gene therapy for inherited metabolic storage diseases / Cathryn Mah -- 20. Retinal diseases / Shannon E. Boye, Sanford L. Boye and William W. Hauswirth -- 21. A brief guide to gene therapy treatments for pulmonary diseases / Ashley T. Martino, Christian Mueller and Terence R. Flotte -- 22. Cardiovascular disease / Darin J. Falk, Cathryn S. Mah and Barry J. Byrne