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Author: Sotiris K Hadjikakou
Publisher: MDPI
Published: 2019-02-05
Total Pages: 257
ISBN-13: 3038975117
DOWNLOAD EBOOKThis book is a printed edition of the Special Issue "A Commemorative Issue in Honor of Professor Nick Hadjiliadis: Metal Complex Interactions with Nucleic Acids and/or DNA" that was published in IJMS
Author: Sotiris K. Hadjikakou
Publisher:
Published: 2019
Total Pages: 1
ISBN-13: 9783038975120
DOWNLOAD EBOOKThis Special Issue of the International Journal of Molecular Science comprises a comprehensive study on "Metal Complex Interactions with Nucleic Acids and/or DNA". This Special Issue has been inspired by the important contribution of Prof. Nick Hadjiliadis to the field of palladium or/and platinum/nucleic acid interactions. It covers a selection of recent research and review articles in the field of metal complex interactions with nucleic acids and/or DNA. Moreover, this Special Issue on "Metal Complexes Interactions with Nucleic Acids and/or DNA" provides an overview of this increasingly diverse field, presenting recent developments and the latest research with particular emphasis on metal-based drugs and metal ion toxicity.
Author: Nick Hadjiliadis
Publisher: John Wiley & Sons
Published: 2009-03-30
Total Pages: 544
ISBN-13: 9781405194105
DOWNLOAD EBOOKMetal ions and metal complexes have long been recognized ascritically important components of nucleic acid chemistry, both inregulation of gene expression and as promising therapeutic agents.Understanding how metal complexes interact with DNA has become anactive research area at the interface between chemistry, molecularbiology and medicine. Metal Complex - DNA Interactions provides a comprehensiveoverview of this increasingly diverse field, presenting recentdevelopments and the latest research with particular emphasis onmetal-based drugs and metal ion toxicity. The text is divided intofour parts: Basic Structural and Kinetic Aspects: includes chapterson sequence-selective metal binding to DNA and thermodynamicmodels. Medical Applications: focuses on anticancer platinumdrugs, including discussions on DNA repair in antitumor effects ofplatinum drugs and photo-dynamic therapy. DNA-Recognition - Nucleases and Sensor: describesprobes for DNA recognition, artificial restriction agents,metallo-DNAzymes for metal sensing applications and metal iondependent catalysis in nucleic acid enzymes. Toxicological Aspects: deals with structural studies ofmercury–DNA interactions, chromium-induced DNA damage andrepair, and the effect of arsenic and nickel on DNAintegrity. This book will be a valuable resource for academic researchersand professionals from a range of pharmaceutical and chemicalindustries, particularly those involved in the development of newand less toxic anticancer metallo-drugs, and in the field ofenvironmental and toxicological chemistry.
Author: Rosalyn D. Blumenthal
Publisher: Humana Press
Published: 2005-02-14
Total Pages: 442
ISBN-13: 9781588295866
DOWNLOAD EBOOKA state-of-the art collection of readily reproducible laboratory methods for assessing chemosensitivity in vitro and in vivo, and for assessing the parameters that modulate chemosensitivity in individual tumors. Chemosensitivity,Volume 2: In Vivo Models, Imaging, and Molecular Regulators contains cutting-edge protocols for classifying tumors into response categories and for customizing therapy to individuals. These readily reproducible techniques allow measurements of DNA damage, apoptotic cell death, and the molecular and cellular regulators of cytotoxicity, as well as in vivo animal modeling of chemosensitivity. A companion volume, Volume 1: In Vitro Assays contains in vitro and in vivo techniques to identify which new agents or combination of agents are effective for each type of tumor.
Author: Trevor M. Letcher
Publisher: Royal Society of Chemistry
Published: 2012
Total Pages: 829
ISBN-13: 1849734070
DOWNLOAD EBOOKAimed at students, lecturers, researchers, and policy makers, this work describes current developments and points the way forward for new developments regarding materials in our society and how they relate to sustainability.
Author: Marco Mascini
Publisher: Royal Society of Chemistry
Published: 2011
Total Pages: 187
ISBN-13: 1849731314
DOWNLOAD EBOOKThis book discusses recent advances in the use of nucleic acid based biosensors and related bioanalytical assays for environmental monitoring.
Author: Masao Ikeda-Saito
Publisher: Royal Society of Chemistry
Published: 2018-10-01
Total Pages: 406
ISBN-13: 1782629912
DOWNLOAD EBOOKThis book highlights the many and varied catalytic activities of O2-dependent heme-iron enzymes, including monoxygenases and cytochrome P450, dioxygenases, oxidases and model heme systems required for postgraduate students and researchers in biochemistry and metallobiology.
Author: Ivano Bertini
Publisher: CRC Press
Published: 2001-06-29
Total Pages: 1382
ISBN-13: 9780824705206
DOWNLOAD EBOOKThis Handbook on Metalloproteins focuses on the available structural information of proteins and their metal ion coordination spheres. It centers on the metal ions indispensable for life but also considers metal ions used as substitution probes in studies of metalloproteins. Emphasizing the structure-function relationship, the book covers the common and distinct characterstics of metallo- enzymes, proteins, and amino acids bonded to copper, zinc, iron, and more.
Author: P.K. Pattengale
Publisher: Springer Science & Business Media
Published: 1985-06-30
Total Pages: 226
ISBN-13: 9780898387254
DOWNLOAD EBOOKProceedings of a symposium presented at the University of Southern California, Department of Pathology and the Kenneth J. Norris Cancer Hospital and Research Institute, Los Angeles, U.S.A., November 16-17, 1984
Author: Chunhai Fan
Publisher: John Wiley & Sons
Published: 2018-05-29
Total Pages: 846
ISBN-13: 3527339868
DOWNLOAD EBOOKMeeting the long-felt need for in-depth information on one of the most advanced material characterization methods, a top team of editors and authors from highly prestigious facilities and institutions covers a range of synchrotron techniques that have proven useful for materials research. Following an introduction to synchrotron radiation and its sources, the second part goes on to describe the various techniques that benefit from this especially bright light, including X-ray absorption, diffraction, scattering, imaging, and lithography. The thrid and final part provides an overview of the applications of synchrotron radiation in materials science. bridging the gap between specialists in synchrotron research and material scientists, this is a unique and indispensable resource for academic and industrial researchers alike.
