This book presents a systematic overview of the most relevant nanomaterials and their respective intrinsic properties that have been highly explored by the scientific community and pharmaceutical companies in several different modalities for cancer therapy and bioimaging. The chapters explore the synergistic effects provided by the different nanostructured materials and highlight the main in vitro and in vivo therapeutic achievements on cancer. This work also provides relevant discussion about the recent progresses and future challenges that nanotechnology faces on the conception of more efficient nanoformulations against primary tumors, circulating cancer cells and metastases.
This book provides a comprehensive summary of the status of emerging sensor technologies and provides a framework for future advances in the field. Chemical sensors have gained in importance in the past decade for applications that include homeland security, medical and environmental monitoring and also food safety. A desirable goal is the ability to simultaneously analyze a wide variety of environmental and biological gases and liquids in the field and to be able to selectively detect a target analyte with high specificity and sensitivity. The goal is to realize real-time, portable and inexpensive chemical and biological sensors and to use these as monitors for handheld gas, environmental pollutant, exhaled breath, saliva, urine, or blood, with wireless capability.In the medical area, frequent screening can catch the early development of diseases, reduce the suffering of patients due to late diagnoses, and lower the medical cost. For example, a 96% survival rate has been predicted in breast cancer patients if the frequency of screening is every three months. This frequency cannot be achieved with current methods of mammography due to high cost to the patient and invasiveness (radiation). In the area of detection of medical biomarkers, many different methods, including enzyme-linked immunsorbent assay (ELISA), particle-based flow cytometric assays, electrochemical measurements based on impedance and capacitance, electrical measurement of microcantilever resonant frequency change, and conductance measurement of semiconductor nanostructures, gas chromatography (GC), ion chromatography, high density peptide arrays, laser scanning quantitiative analysis, chemiluminescence, selected ion flow tube (SIFT), nanomechanical cantilevers, bead-based suspension microarrays, magnetic biosensors and mass spectrometry (MS) have been employed. Depending on the sample condition, these methods may show variable results in terms of sensitivity for some applications and may not meet the requirements for a handheld biosensor.
Magnetic spinels including ferrites are insulating magnetic oxides and chalcogenides with strong coupling to microwave frequencies and low eddy current losses making them indispensable for applications in wireless communications. The 13 chapters and preface of this book discuss other potential applications of magnetic spinels along with various methods used for their synthesis and their varied properties resulting from substituting different metal ions at the A and B sites. These applications include ferrofluids, anticorrosion coatings, absorber coatings for photothermal conversion, biomedicine, and environmental applications such as oxidation of volatile organic compounds and removal of arsenic and heavy metals from water. Emphasis is placed on structure-property correlations and on the nature of magnetism in spinels and their nanoparticles with current information provided for future research.
Nanoscale techniques and devices have had an explosive influence on research in life sciences and bioengineering. Reflecting this influence, Nanopatterning and Nanoscale Devices for Biological Applications provides valuable insight into the latest developments in nanoscale technologies for the study of biological systems. Written and edited by experts in the field, this first-of-its-kind collection of topics: Covers device fabrication methods targeting the substrate on the nanoscale through surface modification Explores the generation of nanostructured biointerfaces and bioelectronics elements Examines microfluidically generated droplets as reactors enabling nanoscale sample preparation and analysis Gives an overview of key biosensors and integrated devices with nanoscale functionalities Discusses the biological applications of nanoscale devices, including a review of nanotechnology in tissue engineering Readers gain a deep understanding of the cutting-edge applications of nanotechnologies in biological engineering, and learn how to apply the relevant scientific concepts to their own research. Nanopatterning and Nanoscale Devices for Biological Applications is the definitive reference for researchers in engineering, biology, and biomedicine, and for anyone exploring the newest trends in this innovative field.
Many aspects of Nature, Biology or even from Society have become part of the techniques and algorithms used in computer science or they have been used to enhance or hybridize several techniques through the inclusion of advanced evolution, cooperation or biologically based additions. The previous NICSO workshops were held in Granada, Spain, 2006, Acireale, Italy, 2007, and in Tenerife, Spain, 2008. As in the previous editions, NICSO 2010, held in Granada, Spain, was conceived as a forum for the latest ideas and the state of the art research related to nature inspired cooperative strategies. The contributions collected in this book cover topics including nature-inspired techniques like Genetic Algorithms, Evolutionary Algorithms, Ant and Bee Colonies, Swarm Intelligence approaches, Neural Networks, several Cooperation Models, Structures and Strategies, Agents Models, Social Interactions, as well as new algorithms based on the behaviour of fireflies or bats.
This chapter discusses fabrication of carbon nanotube yarn and coating of metals and nonmetals onto the yarn to increase electrical conductivity. An increase in weight due to the metal particle coating is the trade-off for achieving increased electrical conductivity. Electrical conductors made from the hybrid alloy yarn may have multiple applications including in electrical conductors and transmission lines. Carbon nanotube yarns also show potential as microelectrodes and robust and flexible chemiresistors for molecular detection. The decoration of metal nanoclusters on the yarn provides high sensitivity and selectivity to gases that are present in industrial and environmental emissions. Overall, coating yarn with particles produces a multifunctional material that opens up new design possibilities for applications.
Health-Promoting Food Ingredients during Processing presents a comprehensive science-based approach covering the latest naturally occurring bioactive compounds in seeds, dietary fiber, proteins, fermented bio-compounds, agro-industrial waste by-products, and lactic acid bacteria. A volume in the Food Biotechnology and Engineering Series, the book discusses their identification, characterization, biological activities in terms of their bioavailability, bioaccessibility, and their beneficial effects as inflammatory mediators, probiotics, antioxidants, and hypoglycemic agents, as well as in gastrointestinal digestion and colonic fermentation. Written by an international expert team of food scientists, nutritionists, food biotechnologists, food engineers, and chemists, the book explains how this leads to opportunities in the treatment of diseases such as obesity, diabetes, cancer, and cognitive disorders. Key features include: · Presents original research and relevant peer-reviewed articles written by experts in disciplines such as food science, nutrition, food biotechnology, food engineering, and chemistry. · Highlights new emerging trends, discoveries, and applications of biologically active compounds from seeds, dietary fiber, proteins, and agro-industrial waste by-products. · Provides readers with a comprehensive, science-based approach to the identification, characterization, and utilization of food macromolecules, probiotics, lactic acid bacteria, and bioactive compounds. - Discusses the impact of bioactive compounds in plants, agroindustrial by-products, and fermented biocompounds regarding their bioavailability, bioaccessibility, and potential human health benefits.
Nanotube Superfiber Materials refers to different forms of macroscale materials with unique properties constructed from carbon nanotubes. These materials include nanotube arrays, ribbons, scrolls, yarn, braid, and sheets. Nanotube materials are in the early stage of development and this is the first dedicated book on the subject. Transitioning from molecules to materials is a breakthrough that will positively impact almost all industries and areas of society. Key properties of superfiber materials are high flexibility and fatigue resistance, high energy absorption, high strength, good electrical conductivity, high maximum current density, reduced skin and proximity effects, high thermal conductivity, lightweight, good field emission, piezoresistive, magnetoresistive, thermoelectric, and other properties. These properties will open up the door to dozens of applications including replacing copper wire for power conduction, EMI shielding, coax cable, carbon biofiber, bullet-proof vests, impact resistant glass, wearable antennas, biomedical microdevices, biosensors, self-sensing composites, supercapacitors, superinductors, hybrid superconductor, reinforced elastomers, nerve scaffolding, energy storage, and many others. The scope of the book covers three main areas: Part I: Processing; Part II: Properties; and Part III: Applications. Processing involves nanotube synthesis and macro scale material formation methods. Properties covers the mechanical, electrical, chemical and other properties of nanotubes and macroscale materials. Different approaches to growing high quality long nanotubes and spinning the nanotubes into yarn are explained in detail. The best ideas are collected from all around the world including commercial approaches. Applications of nanotube superfiber cover a huge field and provides a broad survey of uses. The book gives a broad overview starting from bioelectronics to carbon industrial machines. - First book to explore the production and applications of macro-scale materials made from nano-scale particles - Sets out the processes for producing macro-scale materials from carbon nanotubes, and describes the unique properties of these materials - Potential applications for CNT fiber/yarn include replacing copper wire for power conduction, EMI shielding, coax cable, carbon biofiber, bullet-proof vests, impact resistant glass, wearable antennas, biomedical microdevices, biosensors, self-sensing composites, supercapacitors, superinductors, hybrid superconductor, reinforced elastomers, nerve scaffolding, energy storage, and many others
This text covers ceramic materials from the fundamentals to industrial applications. This includes their impact on the modern technologies, including nano-ceramic, ceramic matrix composites, nanostructured ceramic membranes, porous ceramics, and the sintering theory model of modern ceramics.
After over two decades of focused research and development, silicon carbide (SiC) is now ready for use in the healthcare sector and Silicon Carbide Technology for Advanced Human Healthcare Applications provides an up-to-date assessment of SiC devices for long-term human use. It explores a plethora of applications that SiC is uniquely positioned for in human healthcare, beginning with the three primary areas of technology which are closest to human trials and thus adoption in the healthcare industry: neural implants and spinal cord repair, graphene and biosensors, and finally deep tissue cancer therapy using SiC nanotechnology. Biomedical-inspired engineers, scientists, and healthcare professionals will find this book to be very useful in two ways: (I) as a guide to new ways to design and develop advanced medical devices and (II) as a reference for new developments in the field. The book's intent is to stimulate ideas for further technological enhancements and breakthroughs, which will provide alternative solutions for human healthcare applications. - Discusses the utilization of SiC materials for biomedical applications - Provides a logical pathway to understand why SiC is ideal for several critical applications, in particular for long-term implantable devices, and will serve as a guide to new ways to design and develop advanced medical devices - Serves as a reference for new developments in the field and as a technology resource for medical doctors and practitioners looking to identify and implement advanced engineering solutions to everyday medical challenges that currently lack long-term, cost-effective solutions
