12p Translocations in Acute Leukaemia
Author: Anniek Corveleyn
Publisher: Leuven University Press
Published: 2005
Total Pages: 138
ISBN-13: 9789058674654
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Childhood Acute Lymphoblastic Leukemia
Author: Ajay Vora
Publisher: Springer
Published: 2017-04-21
Total Pages: 345
ISBN-13: 3319397087
DOWNLOAD EBOOKThis book provides a comprehensive and up-to-date review of all aspects of childhood Acute Lymphoblastic Leukemia, from basic biology to supportive care. It offers new insights into the genetic pre-disposition to the condition and discusses how response to early therapy and its basic biology are utilized to develop new prognostic stratification systems and target therapy. Readers will learn about current treatment and outcomes, such as immunotherapy and targeted therapy approaches. Supportive care and management of the condition in resource poor countries are also discussed in detail. This is an indispensable guide for research and laboratory scientists, pediatric hematologists as well as specialist nurses involved in the care of childhood leukemia.
Cancer Cytogenetics
Author: Sverre Heim
Publisher: John Wiley & Sons
Published: 2015-06-29
Total Pages: 645
ISBN-13: 1118795512
DOWNLOAD EBOOKThe first three editions of this acclaimed book presented a much-needed conceptual synthesis of this rapidly moving field. Now, Cancer Cytogenetics, Fourth Edition, offers a comprehensive, expanded, and up-to-date review of recent dramatic advances in this area, incorporating a vast amount of new data from the latest basic and clinical investigations. New contributors reflecting broader international authorship and even greater expertise Greater emphasis throughout on the clinical importance and application of information about cytogenetic and molecular aberrations Includes a complete coverage of chromosome aberrations in cancer based on an assessment of the 60,000 neoplasms cytogenetically investigated to date Now produced in full color for enhanced clarity Covers how molecular genetic data (PCR-based and sequencing information) are collated with the cytogenetic data where pertinent Discusses how molecular cytogenetic data (based on studies using FISH, CGH, SNP, etc) are fused with karyotyping data to enable an as comprehensive understanding of cancer cytogenetics as is currently possible
Catalog of Chromosome Aberrations in Cancer
Author: Felix Mitelman
Publisher: Wiley-Liss
Published: 1994-11-10
Total Pages: 4252
ISBN-13: 9780471111832
DOWNLOAD EBOOKA systematic, concise and uniform presentation of the chromosome changes reported in human neoplastic disorders. Due to the dramatic increase of data, especially on solid tumors which typically have very complex karyotypes, the number of entries has almost doubled in the present edition. This version contains several improvements: all karyotypes have been adjusted according to the ISCN (1991) nomenclature recommendations, extremely complex karyotypes are now displayed unabridged, clonal aberrations are classified by conventional criteria as nonneoplastic disorders/lesions and morphological diagnoses (particularly those of solid tumors) have been reorganized and extended to make retrieval of data on specific tumor types more accessible.
Leukaemia Diagnosis
Author: Barbara J. Bain
Publisher: John Wiley & Sons
Published: 2010-01-28
Total Pages: 404
ISBN-13: 9781444318487
DOWNLOAD EBOOKUP-TO-DATE PRACTICAL GUIDE TO LEUKAEMIA DIAGNOSIS Written by a renowned expert this practical guide had been fullyrevised and updated. The book covers recent advances in the fieldsof immunophenotyping, cytogenetics and molecular genetics. Itillustrates how laboratory techniques are used for the diagnosisand classification of leukaemia and includes images of abnormalcells to aid diagnosis. This fourth edition: Incorporates the recommendations of the 2008 WHO Classificationof Tumours of Haematopoietic and Lymphoid Tissues Includes 300 high quality full colour digital images ofabnormal cells in leukaemia and lymphoma - 50 of which arecompletely new Every haematologist and haematopathologist should keep a copyclose at hand for quick reference.
Allogeneic Stem Cell Transplantation
Author: Hillard M. Lazarus
Publisher: Springer Science & Business Media
Published: 2010-03-02
Total Pages: 885
ISBN-13: 1597454788
DOWNLOAD EBOOKSince the original publication of Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Allogeneic hematopoietic stem cell transplantation (HSC) has undergone several fast-paced changes. In this second edition, the editors have focused on topics relevant to evolving knowledge in the field in order to better guide clinicians in decision-making and management of their patients, as well as help lead laboratory investigators in new directions emanating from clinical observations. Some of the most respected clinicians and scientists in this discipline have responded to the recent advances in the field by providing state-of-the-art discussions addressing these topics in the second edition. The text covers the scope of human genomic variation, the methods of HLA typing and interpretation of high-resolution HLA results. Comprehensive and up-to-date, Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Second Edition offers concise advice on today's best clinical practice and will be of significant benefit to all clinicians and researchers in allogeneic HSC transplantation.
Multiparameter Flow Cytometry in the Diagnosis of Hematologic Malignancies
Author: Anna Porwit
Publisher: Cambridge University Press
Published: 2018-01-25
Total Pages: 248
ISBN-13: 1108548830
DOWNLOAD EBOOKMaster implementation of the techniques of flow cytometry in diagnosing complex haematological diseases and malignancies in patients, worldwide. Featuring World Health Organization recommendations on pre-analytical steps, instrument settings and panel construction, this invaluable manual offers invaluable support for those researching, practising and analyzing the cause of hematological malignancies. Authored by leading experts, this book puts flow-cytometry into everyday context. With a focus on multicolour panels, the manual provides readers an experienced understanding of effective, implementation techniques. Practitioners of all levels are offered a background in a variety of diseases presented alongside the most current methodology. Wide-ranging and comprehensive; detailed images of healthy blood, bone marrow and lymph-nodes are illustrated throughout, allowing for effective diagnosis. Through engaging with differential diagnoses, the manual offers an understanding of similar symptoms and mimicking malignancies, avoiding inaccurate results. Featuring in-depth descriptions of chronic diseases; users can reach accurate diagnosis, first time.
Pocket Guide to Diagnostic Hematopathology
Author: S. David Hudnall
Publisher: Springer
Published: 2019-08-02
Total Pages: 395
ISBN-13: 3030106306
DOWNLOAD EBOOKThis book is designed not as a comprehensive textbook, but instead as a short practical guide to diagnosis of neoplastic and non-neoplastic diseases of blood, bone marrow, and lymphoid tissues. Concise and easy to read, this text provides essential information in a bulleted text format. This simple format was chosen to provide essential information that may quickly be reviewed at the microscope. Each single-page entry begins with a brief one-line Snapshot description, followed by short descriptions of important clinical, morphologic, immunohistochemical, and genetic features, and ending with Caveats and Pearls and Differential Diagnosis. In most cases, entries are accompanied by a few high-quality histologic images. To keep the text concise, recommended texts and recent review articles are cited in the bibliography at the end of the book. To help quickly find alternative diagnoses, the index cross-references all differential diagnoses. The Pocket Guide to Diagnostic Hematopathology should be of use to practicing hematopathologists (academic and private) and hematologic oncologists, as well as trainees (fellows) in hematopathology and hematologic oncology.
Clinical Epidemiology of Acute Lymphoblastic Leukemia
Author: Juan Manuel Mejia-Arangure
Publisher: BoD – Books on Demand
Published: 2013-04-17
Total Pages: 346
ISBN-13: 9535109901
DOWNLOAD EBOOKThis book describes different perspectives of childhood acute lymphoblastic leukemia. The approach includes aspects of molecular epidemiology, particularly molecular features that influence the genesis and prognosis of the disease. Some aspects of the prognosis of lymphoblastic leukemias are very detailed, highlighting the use of molecular biology in the early identification of complications that may occur in diseased patients. The authors of the present book conform a Mexican group who identifies the causes of leukemia, and they summarize their experience in research, results and proposals for future studies. A causal model is included in which the authors hypothesized the origin of acute lymphoblastic leukemias, particularly in children. This hypothesis can be useful to better understand other cancers during childhood. This book will help the reader to identify different molecular aspects involved in leukemia, and its relation to the development and evolution of the disease.
Animal Cell Culture Techniques
Author: Martin Clynes
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 624
ISBN-13: 3642804128
DOWNLOAD EBOOKCell culture techniques allow a variety of molecular and cell biological questions to be addressed, offering physiological conditions whilst avoiding the use of laboratory animals. In addition to basic techniques, a wide range of specialised practical protocols covering the following areas are included: cell proliferation and death, in-vitro models for cell differentiation, in-vitro models for toxicology and pharmacology, industrial application of animal cell culture, genetic manipulation and analysis of human and animal cells in culture.
