Structural DNA Nanotechnology

Structural DNA Nanotechnology

Author: Nadrian C. Seeman

Publisher: Cambridge University Press

Published: 2015

Total Pages: 269

ISBN-13: 0521764483

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Written by the founder of the field, this is a comprehensive and accessible introduction to structural DNA nanotechnology.


Comprehensive Supramolecular Chemistry II

Comprehensive Supramolecular Chemistry II

Author: George W. Gokel

Publisher: Elsevier

Published: 2017-06-22

Total Pages: 4627

ISBN-13: 0128031999

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Comprehensive Supramolecular Chemistry II, Second Edition, Nine Volume Set is a ‘one-stop shop’ that covers supramolecular chemistry, a field that originated from the work of researchers in organic, inorganic and physical chemistry, with some biological influence. The original edition was structured to reflect, in part, the origin of the field. However, in the past two decades, the field has changed a great deal as reflected in this new work that covers the general principles of supramolecular chemistry and molecular recognition, experimental and computational methods in supramolecular chemistry, supramolecular receptors, dynamic supramolecular chemistry, supramolecular engineering, crystallographic (engineered) assemblies, sensors, imaging agents, devices and the latest in nanotechnology. Each section begins with an introduction by an expert in the field, who offers an initial perspective on the development of the field. Each article begins with outlining basic concepts before moving on to more advanced material. Contains content that begins with the basics before moving on to more complex concepts, making it suitable for advanced undergraduates as well as academic researchers Focuses on application of the theory in practice, with particular focus on areas that have gained increasing importance in the 21st century, including nanomedicine, nanotechnology and medicinal chemistry Fully rewritten to make a completely up-to-date reference work that covers all the major advances that have taken place since the First Edition published in 1996


Crystal Engineering of Organic Compounds Including Pharmaceuticals

Crystal Engineering of Organic Compounds Including Pharmaceuticals

Author: Joanna A. Bis

Publisher:

Published: 2006

Total Pages:

ISBN-13:

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Neutral or charge-assisted hydrogen bonds occurring between organic molecules represent strong and directional forces that mediate the molecular self-assembly into well defined supramolecular architectures. A proper understanding of hydrogen bonding interactions, their types, geometries, and occurrence in supramolecular motifs, is a prerequisite to crystal engineering, i.e. to the rational design of functional solid materials. Multiple-component organic crystals represent ideal systems to study the intermolecular interactions between the constituent molecules that can be pre-selected for their hydrogen bonding sites and geometrical capabilities. In particular, the systematic structural analysis of supramolecular systems that are comprised of simple molecules facilitates the development of strategies for the rational design of new multiple-component compounds involving more complex components such as drug molecules. The work presented herein shows a combination of systematic database and experimental studies in the context of reliability and hierarchy of several hydrogen bonded supramolecular synthons that exist in a series of model co-crystals and organic salts. The acquired paradigms are ultimately utilized in crystal engineering of pharmaceuticals. In addition, the viability of a mechanichemical approach toward supramolecular synthesis in the context of its efficacy and the effect on polymorphism in multiple-component compounds is also addressed.


The Crystal as a Supramolecular Entity

The Crystal as a Supramolecular Entity

Author: Gautam R. Desiraju

Publisher: John Wiley & Sons

Published: 2008-04-30

Total Pages: 326

ISBN-13: 0470511427

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Supramolecular chemistry involves the study and synthesis of very large molecules which are used in complex chemical reactions, and have great potential in areas such as medicine, electronics, and optics. Offers a comprehensive overview of crystals and supramolecular entities.


Supramolecular Synthons in Crystal Engineering of Pharmaceutical Properties

Supramolecular Synthons in Crystal Engineering of Pharmaceutical Properties

Author: Ashwini K. Nangia

Publisher: CRC Press

Published: 2024-10-14

Total Pages: 199

ISBN-13: 1040124658

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This comprehensive resource skillfully consolidates crystal engineering, the design of organic solids, and supramolecular synthons (i.e., structural hydrogen bond units) to achieve desired pharmaceutical properties, including solubility, dissolution, bioavailability, permeability, particle size, tableting, hydration, and mechanical strength. Covering 30 years of crystal engineering developments and pharmaceutical applications, this book will be a single and complete resource for supramolecular and structural chemists, the crystal engineering community, pharmaceutical scientists, and industrial researchers. Key Features Covers the fundamentals of crystal engineering and supramolecular synthons. Details the challenges of low solubility and low permeability facing oral drug formulations. Explains how heterosynthons provide a rational approach to address and implement solutions. Provides case studies from academic and industrial labs to walk the reader through the actual steps. Explores developments in the scale up and manufacture of crystal forms in pharmaceutical industry.


Molecular Self-Assembly

Molecular Self-Assembly

Author: Makoto Fujita

Publisher: Springer

Published: 2003-09-04

Total Pages: 255

ISBN-13: 354046591X

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Self-assembly is undoubtedly a topic of special interest in current chemistry and is related to very wide scientific areas. Recent progress in this field seems to be featured by the construction of well-defined discrete systems exploiting complementary hydrogen bonding as well as coordination bonding. Seven leading international experts introduce the current topics in this very interesting field, focusing on two major subjects: organic assemblies and inorganic assemblies. All researchers who are interested in molecular recognition, material science, nanotechnology, and supramolecular chemistry will welcome this book as an inspiring source for creative research ideas.


Self-Assembling Systems

Self-Assembling Systems

Author: Li-Tang Yan

Publisher: John Wiley & Sons

Published: 2016-12-19

Total Pages: 391

ISBN-13: 1119113148

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Provides comprehensive knowledge on concepts, theoretical methods and state-of-the-art computational techniques for the simulation of self-assembling systems Looks at the field of self-assembly from a theoretical perspective Highlights the importance of theoretical studies and tailored computer simulations to support the design of new self-assembling materials with useful properties Divided into three parts covering the basic principles of self-assembly, methodology, and emerging topics