Physical Properties of Biological Membranes and Their Functional Implications
Physical Properties of Biological Membranes and Their Functional Implications

Author: Cecilia Hidalgo

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 242

ISBN-13: 1461309352

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This book was originated from a series of lectures given in a course on the physical properties of biological membranes and their functional implica tions. The course was intended to allow students to get acquainted with the physical techniques used to study biological membranes. The experience was valuable and we feel that a detailed description of the procedures used and of various examples of the results obtained allowed many students to become familiar with a theme that is not often part of regular courses on membrane physiology or biophysics. This book is designed as a tutorial guide for graduate students interested in understanding how physical methods can be utilized to study the proper ties of biological membranes. It includes first a detailed description of applications of physical techniques-such as X-ray fiber diffraction methods (Chapter 1), 2H and 13C NMR spectroscopy (Chapter 2), and calorimetry (Chapter 3)-in the study of the properties of lipid model membranes. A description of how to measure molecular mobility in membranes (Chapter 4) follows, and the book concludes with three chapters in which biological membranes are the subject of study. Chapter 5 deals with the acetylcholine receptor and its membrane environment; Chapter 6 discusses how fluorescence techniques can be applied in the study of the calcium ATPase of sarcoplasmic reticulum; and Chapter 7 explains how protein lipid interactions modulate the function of the sodium and proton pumps.

Water Transport and Biological Membranes
Water Transport and Biological Membranes

Author: Gheorghe Benga

Publisher: CRC Press

Published: 2018-05-04

Total Pages: 300

ISBN-13: 1351086103

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The main purpose of this book is to provide in-depth presentation of physical techniques for measuring water transport and their applications to a variety of biological membranes, from model membrane systems to cell membranes, and then from isolated cells to multicellular barrier systems, such as epithelia or even whole organisms. This survey of water transport in such a broad range of membrane systems will hopefully contribute to understanding of the structure-function relationships and molecular mechanisms of water permeation. Moreover, the description of various techniques, together with a review of literature will enable the readers to assess whether a technique would be useful in helping to solve his or her particular problem of research and will also expand their competence in these techniques. The book consists of two volumes.

The Physical Chemistry of MEMBRANES
The Physical Chemistry of MEMBRANES

Author: B. Silver

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 413

ISBN-13: 9401096287

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Ls book is an account of what physical chemistry h . . to say about the structural, electrical and transport properties of biological membranes and their simplest model-the lipid bilayer. The accent throughout is on basic ideas. In contrast to the essentially descriptive ap proach characteristic of texts on membrane biochemistry, our underlying themes are the role of force and entropy in maintaining membrane organization, in determining the electric fields and ionic environment of membranes, and in regulating the passage of molecules and ions across membranes. Although experimental findings will always be the touch stone against which theory will be tried, no attempt is made to present an exhaustive survey of experimental data. On the other hand, there is discussion of the nature and limitations of the results obtainable by the major laboratory techniques. The treatment is at the level of an advanced undergraduate course or an introductory survey suitable for post graduate students carrying out research in biochemistry, biophysics, or physiology. The mathematical demands on the reader are trivial. The few forbidding equations appearing in Chapter 7 are soon whittled away to simple practical expressions. Although the current-voltage characteristics of nerves are traditionally the province of biophysics rather than physical chemistry, certain aspects relevant to the electrical activity of nerves are nevertheless included in this text, namely, mem brane and diffusion potentials and conductivity fluctuations. Where rival theories exist, conflicting convictions have been presented, but not necessarily accorded equal approbation. The author has a viewpoint.

An Introduction to Biological Membranes
An Introduction to Biological Membranes

Author: William Stillwell

Publisher: Newnes

Published: 2013-04-20

Total Pages: 379

ISBN-13: 0080931286

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An Introduction to Biological Membranes: From Bilayers to Rafts covers many aspects of membrane structure/function that bridges membrane biophysics and cell biology. Offering cohesive, foundational information, this publication is valuable for advanced undergraduate students, graduate students and membranologists who seek a broad overview of membrane science. Brings together different facets of membrane research in a universally understandable manner Emphasis on the historical development of the field Topics include membrane sugars, membrane models, membrane isolation methods, and membrane transport

The Enzymes of Biological Membranes
The Enzymes of Biological Membranes

Author: Anthony N. Martonosi

Publisher: Springer

Published: 1976-03

Total Pages: 488

ISBN-13:

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The romantic phase of membrane biochemistry characterized by conceptual develop ments and an essentially unlimited freedom of choice is gradually coming to a close. Attention is turning from the general, qualitative description of membrane structure toward the specific properties of membrane-linked enzymes and metabolic systems. The purpose of this series is to serve this development by collecting and evaluating the mass of interesting information that is already available widely scattered in the literature. The emphasis will be upon a comprehensive treatment of membrane linked enzymes from the viewpoint of modern enzymology. The general properties of membranes will be mentioned only to the extent that they are relevant to the dis cussion of the enzymes in question. The first of the four volumes will deal with the physical and chemical techniques (X-ray crystallography, nuclear magnetic and electron spin resonance, fluorescence spectroscopy, immunology, etc.) used in the characterization of membrane enzymes. Chapters are also included on artificial bilayer membranes, chemical modification of membrane enzymes, and on the nature of lipid-protein interaction in membranes. In the next three volumes the enzyme systems participating in the biosynthesis of cell components, active transport, oxydative phosphorylation, and photosynthesis will be analyzed. A brief discussion of hormone receptors is also included. Subsequent volumes may fill in the few but significant gaps in the coverage that for various reasons could not be avoided.

Membrane Hydration
Membrane Hydration

Author: E. Anibal Disalvo

Publisher: Springer

Published: 2015-10-14

Total Pages: 0

ISBN-13: 9783319190594

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This book is about the importance of water in determining the structure, stability and responsive behavior of biological membranes. Water confers to lipid membranes unique features in terms of surface and mechanical properties. The analysis of the hydration forces, plasticiser effects, controlled hydration, formation of microdomains of confined water suggests that water is an active constituent in a water-lipid system. The chapters describe water organization at the lipid membrane–water interphase, the water penetration, the long range water structure in the presence of lipid membranes by means of X-ray and neutron scattering, general polarization, fluorescent probes, ATR-FTIR and near infrared spectroscopies, piezo electric methods, computer simulation and surface thermodynamics. Permeation, percolation, osmotic stress, polarization, protrusion, sorption, hydrophobicity, density fluctuations are treated in detail in self-assembled bilayers. Studies in lipid monolayers show the correlation of surface pressure with water activity and its role in peptide and enzyme interactions. The book concludes with a discussion on anhydrobiosis and the effect of water replacement in microdomains and its consequence for cell function. New definitions of lipid/water interphases consider water not only as a structural-making solvent but as a mediator in signalling metabolic activity, modulating protein insertion and enzymatic activity, triggering oscillatory reactions and functioning of membrane bound receptors. Since these effects occur at the molecular level, membrane hydration appears fundamental to understand the behavior of nano systems and confined environments mimicking biological systems. These insights in structural, thermodynamical and mechanical water properties give a base for new paradigms in membrane structure and function for those interested in biophysics, physical chemistry, biology, bio and nano medicine, biochemistry, biotechnology and nano sciences searching for biotechnological inputs in human health, food industry, plant growing and energy conversion.

Physics of Biological Membranes
Physics of Biological Membranes

Author: Patricia Bassereau

Publisher: Springer

Published: 2018-12-30

Total Pages: 623

ISBN-13: 3030006301

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This book mainly focuses on key aspects of biomembranes that have emerged over the past 15 years. It covers static and dynamic descriptions, as well as modeling for membrane organization and shape at the local and global (at the cell level) scale. It also discusses several new developments in non-equilibrium aspects that have not yet been covered elsewhere. Biological membranes are the seat of interactions between cells and the rest of the world, and internally, they are at the core of complex dynamic reorganizations and chemical reactions. Despite the long tradition of membrane research in biophysics, the physics of cell membranes as well as of biomimetic or synthetic membranes is a rapidly developing field. Though successful books have already been published on this topic over the past decades, none include the most recent advances. Additionally, in this domain, the traditional distinction between biological and physical approaches tends to blur. This book gathers the most recent advances in this area, and will benefit biologists and physicists alike.