Félix d`Herelle and the Origins of Molecular Biology
Félix d`Herelle and the Origins of Molecular Biology

Author: William C. Summers

Publisher: Yale University Press

Published: 1999-06-10

Total Pages: 272

ISBN-13: 9780300174250

DOWNLOAD EBOOK

A self-taught scientist determined to bring science out of the laboratory and into the practical arena, French-Canadian Felix d’Herelle (1873-1949) made history in two different fields of biology. Not only was he first to demonstrate the use and application of bacteria for biological control of insect pests, he also became a seminal figure in the history of molecular biology. This engaging book is the first full biography of d’Herelle, a complex figure who emulated Louis Pasteur and influenced the course of twentieth-century biology, yet remained a controversial outsider to the scientific community. Drawing on family papers, archival sources, interviews, and d’Herelle’s published and unpublished writings, Dr. William C. Summers tells the fascinating story of the scientist’s life and the work that took him around the globe. In 1917, d’Herelle published the first paper describing the phenomenon of the bacteriophage and its biological nature. A series of more than 110 articles and 6 major books followed, in which d’Herelle established the foundation for the later work of the Phage Group in molecular biology. Yet d’Herelle sometimes inspired animosity in others--he was drummed out of the Pasteur Institute, he held only one brief permanent position in the scientific establishment (at Yale University from 1928 to 1933), and he was bewildered by the social nuances of the world of international science. His story is more than the biography of a single brilliant scientist; it is also a fascinating chapter in the history of biology.

Felix D'Herelle and the Origins of Molecular Biology
Felix D'Herelle and the Origins of Molecular Biology

Author: William Summers

Publisher:

Published: 2007-12

Total Pages: 230

ISBN-13: 9781422353585

DOWNLOAD EBOOK

A self-taught scientist determined to bring science out of the lab. & into the practical arena, d¿Herelle (1873-1949) made history in 2 different fields of biology. He was first to demonstrate the use & application of bacteria for biological control of insect pests, & also became a seminal figure in the history of molecular biology. d¿Herelle was a complex figure who emulated Louis Pasteur & influenced the course of 20th-century biology, yet remained a controversial outsider to the scientific community. Summers tells the fascinating story of the scientist¿s life & the work that took him around the globe. ¿This biography of a single brilliant scientist is also a fascinating chapter in the history of biology.¿ ¿Marvelous historical sensibility.¿ Illustrations

Arrowsmith
Arrowsmith

Author: Sinclair Lewis

Publisher: Simon and Schuster

Published: 2021-03-23

Total Pages: 390

ISBN-13: 1649741286

DOWNLOAD EBOOK

Arrowsmith has been inspirational for several generations of med students. Martin Arrowsmith agonizes over his career and life decisions never sure if he’s making the correct descisions. While the book details Arrowsmith's pursuit of the noble ideals of medical research for the benefit of mankind and of selfless devotion to the care of patients, Lewis throws many less noble temptations and self deceptions in Arrowsmith’s path. The attractions of financial security, recognition, even wealth and power distract Arrowsmith from his original plan to follow in the footsteps of his first mentor, Max Gottlieb, a brilliant but abrasive bacteriologist. A powerful novel that asks more questions than it answers. Winner of the Pulitzer Prize.

A Tale of Two Viruses
A Tale of Two Viruses

Author: Neeraja Sankaran

Publisher: University of Pittsburgh Press

Published: 2021-03-09

Total Pages: 410

ISBN-13: 0822987716

DOWNLOAD EBOOK

In 1965, French microbiologist André Lwoff was awarded the Nobel Prize in Physiology or Medicine for his work on lysogeny—one of the two types of viral life cycles—which resolved a contentious debate among scientists about the nature of viruses. A Tale of Two Viruses is the first study of medical virology to compare the history of two groups of medically important viruses—bacteriophages, which infect bacteria, and sarcoma agents, which cause cancer—and the importance of Lwoff’s discovery to our modern understanding of what a virus is. Although these two groups of viruses may at first glance appear to have little in common, they share uniquely parallel histories. The lysogenic cycle, unlike the lytic, enables viruses to replicate in the host cell without destroying it and to remain dormant in a cell’s genetic material indefinitely, or until induced by UV radiation. But until Lwoff’s discovery of the mechanism of lysogeny, microbiologist Félix d’Herelle and pathologist Peyton Rous, who themselves first discovered and argued for the viral identity of bacteriophages and certain types of cancer, respectively, faced opposition from contemporary researchers who would not accept their findings. By following the research trajectories of the two virus groups, Sankaran takes a novel approach to the history of the development of the field of medical virology, considering both the flux in scientific concepts over time and the broader scientific landscapes or styles that shaped those ideas and practices.

Bacteriophages
Bacteriophages

Author: David R. Harper

Publisher: Springer Nature

Published: 2021-01-30

Total Pages: 1376

ISBN-13: 3319419862

DOWNLOAD EBOOK

This first major reference work dedicated to the mannifold industrial and medical applications of bacteriophages provides both theoretical and practical insights into the emerging field of bacteriophage biotechnology. The book introduces to bacteriophage biology, ecology and history and reviews the latest technologies and tools in bacteriophage detection, strain optimization and nanotechnology. Usage of bacteriophages in food safety, agriculture, and different therapeutic areas is discussed in detail. This book serves as essential guide for researchers in applied microbiology, biotechnology and medicine coming from both academia and industry.

The Perfect Predator
The Perfect Predator

Author: Steffanie Strathdee

Publisher: Hachette Books

Published: 2019-02-26

Total Pages: 346

ISBN-13: 0316418072

DOWNLOAD EBOOK

An electrifying memoir of one woman's extraordinary effort to save her husband's life-and the discovery of a forgotten cure that has the potential to save millions more. "A memoir that reads like a thriller." -New York Times Book Review "A fascinating and terrifying peek into the devastating outcomes of antibiotic misuse-and what happens when standard health care falls short." -Scientific American Epidemiologist Steffanie Strathdee and her husband, psychologist Tom Patterson, were vacationing in Egypt when Tom came down with a stomach bug. What at first seemed like a case of food poisoning quickly turned critical, and by the time Tom had been transferred via emergency medevac to the world-class medical center at UC San Diego, where both he and Steffanie worked, blood work revealed why modern medicine was failing: Tom was fighting one of the most dangerous, antibiotic-resistant bacteria in the world. Frantic, Steffanie combed through research old and new and came across phage therapy: the idea that the right virus, aka "the perfect predator," can kill even the most lethal bacteria. Phage treatment had fallen out of favor almost 100 years ago, after antibiotic use went mainstream. Now, with time running out, Steffanie appealed to phage researchers all over the world for help. She found allies at the FDA, researchers from Texas A&M, and a clandestine Navy biomedical center -- and together they resurrected a forgotten cure. A nail-biting medical mystery, The Perfect Predator is a story of love and survival against all odds, and the (re)discovery of a powerful new weapon in the global superbug crisis.

We Can Sleep Later
We Can Sleep Later

Author: Alfred Day Hershey

Publisher: CSHL Press

Published: 2000

Total Pages: 396

ISBN-13: 9780879695675

DOWNLOAD EBOOK

An absorbing portrait of the pioneering molecular biologist best known for demonstrating that DNA is the genetic component of phages, through essays and reminiscences from twenty–three distinguished scientists whose work and careers were influenced by the man and his science.

Current Protocols Essential Laboratory Techniques
Current Protocols Essential Laboratory Techniques

Author: Sean R. Gallagher

Publisher: John Wiley & Sons

Published: 2012-03-19

Total Pages: 679

ISBN-13: 047094241X

DOWNLOAD EBOOK

The latest title from the acclaimed Current Protocols series, Current Protocols Essential Laboratory Techniques, 2e provides the new researcher with the skills and understanding of the fundamental laboratory procedures necessary to run successful experiments, solve problems, and become a productive member of the modern life science laboratory. From covering the basic skills such as measurement, preparation of reagents and use of basic instrumentation to the more advanced techniques such as blotting, chromatography and real-time PCR, this book will serve as a practical reference manual for any life science researcher. Written by a combination of distinguished investigators and outstanding faculty, Current Protocols Essential Laboratory Techniques, 2e is the cornerstone on which the beginning scientist can develop the skills for a successful research career.

Bacteriophage Ecology
Bacteriophage Ecology

Author: Stephen T. Abedon

Publisher: Cambridge University Press

Published: 2008-05-01

Total Pages: 457

ISBN-13: 1139471945

DOWNLOAD EBOOK

Bacteriophages, or phages, are viruses that infect bacteria and are believed to be the most abundant and genetically diverse organisms on Earth. As such, their ecology is vast both in quantitative and qualitative terms. Their abundance makes an understanding of phage ecology increasingly relevant to bacterial ecosystem ecology, bacterial genomics and bacterial pathology. Abedon provides the first text on phage ecology for almost 20 years. Written by leading experts, synthesizing the three key approaches to studying phage ecology, namely studying them in natural environments (in situ), experimentally in the lab, or theoretically using mathematical or computer models. With strong emphasis on microbial population biology and distilling cutting-edge research into basic principles, this book will complement other currently available volumes. It will therefore serve as an essential resource for graduate students and researchers, particularly those with an interest in phage ecology and evolutionary biology.