Engineering Biomaterials for Neural Applications
Engineering Biomaterials for Neural Applications

Author: Elisa López-Dolado

Publisher: Springer Nature

Published: 2022-03-25

Total Pages: 327

ISBN-13: 3030814009

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This book describes past and present advances in engineering materials for neural applications, with special emphasis on their usefulness for traumatic brain and spinal cord injuries. The book presents major physio-pathological features of traumatic injuries at the brain and spinal cord as examples of diseases hampering the central nervous tissue. By incorporating knowledge from the perspective of experts with diverse backgrounds, this book gives insight into the understanding of these multifaceted pathologies and the materials science approaches that aim to cure them. The interdisciplinary nature of this book makes it a perfect candidate for the interest of a broad audience, from clinicians working on neural diseases to scientists whose work focuses on the nervous tissue (neuroscientists) and/or materials science. Undergraduate and PhD students can also benefit from the knowledge and discussion included in this book.

Biomaterials for Tissue Engineering Applications
Biomaterials for Tissue Engineering Applications

Author: Jason A. Burdick

Publisher: Springer Science & Business Media

Published: 2010-12-07

Total Pages: 562

ISBN-13: 3709103851

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A concise overview of tissue engineering technologies and materials towards specific applications, both past and potential growth areas in this unique discipline is provided to the reader. The specific area of the biomaterial component used within the paradigm of tissue engineering is examined in detail. This is the first work to specifically covers topics of interest with regards to the biomaterial component. The book is divided into 2 sections: (i) general materials technology (e.g., fibrous tissue scaffolds) and (ii) applications in the engineering of specific tissues (e.g., materials for cartilage tissue engineering). Each chapter covers the fundamentals and reflects not only a review of the literature, but also addresses the future of the topic. The book is intended for an audience of researchers in both industry and academia that are interested in a concise overview regarding the biomaterials component of tissue engineering, a topic that is timely and only growing as a field.

Neural Engineering
Neural Engineering

Author: Lijie Grace Zhang

Publisher: Springer

Published: 2016-06-29

Total Pages: 311

ISBN-13: 3319314335

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This book covers the principles of advanced 3D fabrication techniques, stem cells and biomaterials for neural engineering. Renowned contributors cover topics such as neural tissue regeneration, peripheral and central nervous system repair, brain-machine interfaces and in vitro nervous system modeling. Within these areas, focus remains on exciting and emerging technologies such as highly developed neuroprostheses and the communication channels between the brain and prostheses, enabling technologies that are beneficial for development of therapeutic interventions, advanced fabrication techniques such as 3D bioprinting, photolithography, microfluidics, and subtractive fabrication, and the engineering of implantable neural grafts.There is a strong focus on stem cells and 3D bioprinting technologies throughout the book, including working with embryonic, fetal, neonatal, and adult stem cells and a variety of sophisticated 3D bioprinting methods for neural engineering applications. There is also a strong focus on biomaterials, including various conductive biomaterials and biomimetic nanomaterials such as carbon-based nanomaterials and engineered 3D nanofibrous scaffolds for neural tissue regeneration. Finally, two chapters on in vitro nervous system models are also included, which cover this topic in the context of studying physiology and pathology of the human nervous system, and for use in drug discovery research. This is an essential book for biomedical engineers, neuroscientists, neurophysiologists, and industry professionals.

Biomaterials for Neural Tissue Engineering
Biomaterials for Neural Tissue Engineering

Author: Oguzhan Gunduz

Publisher: Elsevier

Published: 2023-04-18

Total Pages: 482

ISBN-13: 0323906745

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Biomaterials for Neural Tissue Engineering covers a range of materials and technologies used for regenerating or repairing neural tissue. With a strong focus on biomaterials and scaffolds, the book examines the testing and evaluation pathway for in-vitro and in-vivo testing trials. This book introduces the reader to the fundamentals of the nervous system from a tissue engineering perspective and goes on to describe contemporary technologies used in the development of neural repair materials, as well as currently available biomaterials suitable for neural tissue repair and regeneration. This detailed reference is ideal for those who are new to using biomaterials in tissue engineering, particularly those interested in the nervous system, including academics and early career researchers in the fields of materials science, regenerative medicine, biomedical engineering and clinical sciences. Provides readers entering the field with a core introduction to neural tissue engineering processes and real-world applications Comprehensively examines a variety of biomaterial approaches Discusses the most current in-vitro and in-vivo testing and their importance in treating nervous system disorders Details a broad range of natural and synthetic biomaterials used to engineer neural tissue

Engineering Biomaterials for Neural Applications
Engineering Biomaterials for Neural Applications

Author: Elizabeth Nance

Publisher:

Published: 2022

Total Pages: 0

ISBN-13: 9783031114106

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This contributed volume explores the ways in which researchers engineer new biomaterials for the challenging problems of the peripheral and central nervous systems. These biomaterials are uniquely positioned for use in creating in vitro models of injury and disease, testing therapeutic treatments, understanding neural development, and mapping the multi-scalar environment of the brain. This book informs readers from biology, chemistry, materials science, engineering, and neuroscience on cutting edge research in engineering technologies, from fundamental material development through pre-clinical studies. The book also highlights target applications in three areas of research: (1) engineering neural models and materials, (2) probing biological underpinnings of neurological function and disease, and (3) designing therapeutic and diagnostic treatments for neurological disease. .

Engineering Biomaterials for Neural Applications
Engineering Biomaterials for Neural Applications

Author: Elizabeth Nance

Publisher: Springer Nature

Published: 2022-10-28

Total Pages: 354

ISBN-13: 3031114094

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This contributed volume explores the ways in which researchers engineer new biomaterials for the challenging problems of the peripheral and central nervous systems. These biomaterials are uniquely positioned for use in creating in vitro models of injury and disease, testing therapeutic treatments, understanding neural development, and mapping the multi-scalar environment of the brain. This book informs readers from biology, chemistry, materials science, engineering, and neuroscience on cutting edge research in engineering technologies, from fundamental material development through pre-clinical studies. The book also highlights target applications in three areas of research: (1) engineering neural models and materials, (2) probing biological underpinnings of neurological function and disease, and (3) designing therapeutic and diagnostic treatments for neurological disease.

Central Nervous System Tissue Engineering
Central Nervous System Tissue Engineering

Author: A. E. Wilkinson

Publisher: Morgan & Claypool Publishers

Published: 2011-11-11

Total Pages: 122

ISBN-13: 1608457877

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Combating neural degeneration from injury or disease is extremely difficult in the brain and spinal cord, i.e. central nervous system (CNS). Unlike the peripheral nerves, CNS neurons are bombarded by physical and chemical restrictions that prevent proper healing and restoration of function. The CNS is vital to bodily function, and loss of any part of it can severely and permanently alter a person's quality of life. Tissue engineering could offer much needed solutions to regenerate or replace damaged CNS tissue. This review will discuss current CNS tissue engineering approaches integrating scaffolds, cells and stimulation techniques. Hydrogels are commonly used CNS tissue engineering scaffolds to stimulate and enhance regeneration, but fiber meshes and other porous structures show specific utility depending on application. CNS relevant cell sources have focused on implantation of exogenous cells or stimulation of endogenous populations. Somatic cells of the CNS are rarely utilized for tissue engineering; however, glial cells of the peripheral nervous system (PNS) may be used to myelinate and protect spinal cord damage. Pluripotent and multipotent stem cells offer alternative cell sources due to continuing advancements in identification and differentiation of these cells. Finally, physical, chemical, and electrical guidance cues are extremely important to neural cells, serving important roles in development and adulthood. These guidance cues are being integrated into tissue engineering approaches. Of particular interest is the inclusion of cues to guide stem cells to differentiate into CNS cell types, as well to guide neuron targeting. This review should provide the reader with a broad understanding of CNS tissue engineering challenges and tactics, with the goal of fostering the future development of biologically inspired designs. Table of Contents: Introduction / Anatomy of the CNS and Progression of Neurological Damage / Biomaterials for Scaffold Preparation / Cell Sources for CNS TE / Stimulation and Guidance / Concluding Remarks

Biomaterials and Tissue Engineering
Biomaterials and Tissue Engineering

Author:

Publisher: 清华大学出版社有限公司

Published: 2004

Total Pages: 272

ISBN-13: 9787302058816

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本书共有5 章,分别是:生物活性材料、材料的生物适应性、无机玻璃的生物学应用、对于生活工艺学的生物合成材料以及细胞组织工艺学。

Engineering Biomaterials for Regenerative Medicine
Engineering Biomaterials for Regenerative Medicine

Author: Sujata K. Bhatia

Publisher: Springer Science & Business Media

Published: 2011-11-10

Total Pages: 350

ISBN-13: 1461410800

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Regeneration of tissues and organs remains one of the great challenges of clinical medicine, and physicians are constantly seeking better methods for tissue repair and replacement. Tissue engineering and regenerative medicine have been investigated for virtually every organ system in the human body, and progress is made possible by advances in materials science, polymer chemistry, and molecular biology. This book reviews the current status of biomaterials for regenerative medicine, and highlights advances in both basic science and clinical practice. The latest methods for regulating the biological and chemical composition of biomaterials are described, together with techniques for modulating mechanical properties of engineered constructs. Contributors delineate methods for guiding the host response to implantable materials, and explain the use of biologically-inspired materials for optimal biological functionality and compatibility. The book culminates in a discussion of the clinical applications of regenerative medicine. By integrating engineering and clinical medicine, Engineering Biomaterials for Regenerative Medicine examines how tissue engineering and regenerative medicine can be translated into successful therapies to bridge the gap between laboratory and clinic. The book will aid materials scientists and engineers in identifying research priorities to fulfill clinical needs, and will also enable physicians to understand novel biomaterials that are emerging in the clinic. This integrated approach also gives engineering students a sense of the excitement and relevance of materials science in the development of novel therapeutic strategies.

Biomaterials Engineering and Devices: Human Applications
Biomaterials Engineering and Devices: Human Applications

Author: Donald L. Wise

Publisher: Springer Science & Business Media

Published: 2000-08-01

Total Pages: 345

ISBN-13: 1592591965

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Authoritative international experts comprehensively review many current state-of-the-art uses of polymers, metals, and ceramics in the human body. A veritable encyclopedia of valuable data and experience, this volume not only fully addresses the major issues of compatibility and functionality, but also provides a technical treatise on the design and evaluation of biomaterials for vascular application and on biomaterials as carriers for bioactive agents. A second volume, Biomaterials Engineering and Devices: Human Applications, Volume 2 is devoted to biomaterials for dental applications, bony biomaterials for grafting applications, and orthopedic fixtures and cements. Extensively illustrated and referenced, Biomaterials Engineering and Devices: Human Applications, Volume 1: Fundamentals and Vascular and Carrier Applications integrates for today's bioengineering professionals the basic science, engineering, and practical medical experience needed to meet the ever-growing demand for new and better biomaterials.